55 Questions
Which coenzyme is required for enzyme-catalyzed transamination between an amino acid and an alpha keto acid?
Pyridoxal phosphate
Which amino acid pairs are exclusively ketogenic?
Leucine and lysine
What is the name of the covalent bond that links nucleotides in a nucleic acid?
Phosphodiester
Which of these causes sickle cell anemia?
A missense mutation
What process greatly improves the fidelity of DNA polymerases delta (δ) and epsilon (ε), but not DNA polymerase alpha (α)?
Proofreading
Why do all individuals contain DNA molecules that were synthesized by their ancestors in addition to the DNA synthesized by that individual?
Because replication is semi-conservative
What is the enzymatic process that makes a completely new copy of the DNA genome prior to each cell division called?
Replication
In eukaryotes, synthesis of 3 out of the 4 ribosomal RNAs is catalyzed by which RNA polymerase?
RNA polymerase I
What molecule attaches to the CCA sequence at the 3' end of tRNA?
An amino acid
Which of these selectively inhibits eukaryotic RNA polymerase II?
Alpha (a)-amanitin
In the CRISPR-Cas 9 method for gene editing, the endonuclease is guided by the target:
RNA
What is needed for the post-translational modification of collagen and for the synthesis of many other molecules including carnitine?
Vitamin C
Which of these protein factors facilitate the initiation of transcription in prokaryotes?
Sigma
What is the role of ubiquitin ligase in biochemical processes?
It targets proteins for degradation
Which of the following is an example of a plasma protein involved in blood clotting?
Fibrinogen
What is the main function of telomerase in biochemical processes?
Maintaining telomere length
Which biochemical process involves the synthesis of nucleotides?
DNA replication
What is the impact of mutations on splicing?
Altered mRNA processing
Which of the following is an example of a genetic mutation affecting human health?
Sickle cell anemia
What is the specific function of histones in biochemical processes?
DNA packaging and regulation of gene expression
Which enzyme is involved in the synthesis of new DNA strands during DNA replication?
DNA polymerases
What is the impact of telomere maintenance on biological processes?
Preservation of genomic stability
Which biochemical process involves the urea cycle?
Metabolism of nitrogenous waste
What is the application of telomerase inhibitors in the context of human health?
Anti-cancer treatment
Which biochemical process involves the use of dideoxyribonucleotides?
DNA sequencing
Which enzyme is involved in the synthesis of new DNA strands during DNA replication?
DNA polymerase III
What is the role of ubiquitin ligase in biochemical processes?
Tagging proteins for degradation
What is the specific function of histones in biochemical processes?
Packaging DNA into structural units called nucleosomes
Which of the following is an example of a plasma protein involved in blood clotting?
Fibrinogen
What is the application of telomerase inhibitors in the context of human health?
Potential anti-cancer therapy
What is the enzymatic process that makes a completely new copy of the DNA genome prior to each cell division called?
DNA replication
What is the impact of mutations on splicing?
Altered mRNA processing
Which biochemical process involves the synthesis of nucleotides?
DNA replication
What is the main function of telomerase in biochemical processes?
Preventing telomere shortening
Which of these selectively inhibits eukaryotic RNA polymerase II?
Alpha-amanitin
Which enzyme is deficient in the 9-year-old girl with mild mental retardation and elevated levels of leucine, isoleucine, and valine?
Branched chain alpha keto acid dehydrogenase
Which amino acid deficiency in the protein of the island vegetation is more likely to cause negative nitrogen balance in a man marooned on a desert island?
Methionine
Which coenzyme is required for enzyme-catalyzed transamination between an amino acid and an alpha keto acid?
Pyridoxal phosphate
Sulfonamides have been useful anti-bacterial agents because they inhibit the synthesis of:
Folic acid
Which enzymatic activity is usually deficient in phenylketonuria?
A hydroxylase
Which of the following amino acid pairs are exclusively ketogenic?
Leucine and lysine
Which amino acid is exclusively glucogenic and dietary non-essential?
Alanine
Which enzyme catalyzes a reaction that yields an alpha keto acid, NADH, and ammonia?
Aminotransferase
Which enzyme is involved in the rate-determining step of the urea cycle?
Carbamoyl phosphate synthetase I
Which of the following is a coenzyme required for the enzymatic activity that is usually deficient in phenylketonuria?
Tetrahydrobiopterin
Which enzyme catalyzes the attachment of amino acids to the CCA sequence at the 3' end of tRNAs?
Aminoacyl tRNA synthetases
What molecule attaches to the CCA sequence at the 3' end of tRNA?
An amino acid
What is the name of the covalent bond that links nucleotides in a nucleic acid?
Phosphodiester
What process greatly improves the fidelity of DNA polymerases delta (δ) and epsilon (ε), but not DNA polymerase alpha (α)?
Proofreading
Which of these components are required for RNA synthesis?
A template, a free 3' hydroxyl group, RNA polymerase, NTPs
Which of these directly enhances the initiation of transcription?
TATA-binding protein (TBP)
Which of these essential sugars forms a ring involving 4 carbon atoms and one oxygen atom?
Ribose
Which of these pyrimidines is uniquely found in RNA?
Uracil
Which of these selectively inhibits eukaryotic RNA polymerase II?
Alpha (α)-amanitin
In the CRISPR-Cas 9 method for gene editing, the endonuclease is guided by the target:
RNA
Study Notes
Biochemistry Practice Quiz Summaries
- The text consists of three practice quizzes covering topics such as protein turnover, plasma proteins, and nucleotide synthesis.
- The quizzes cover various biochemical processes including protein modification, blood clotting, and DNA synthesis.
- The quizzes include questions on specific enzymes and their functions, such as glutamate dehydrogenase, heme oxygenase, and thymidylate synthase.
- Important concepts such as the role of ubiquitin ligase in protein turnover, the action of plasma proteins in blood clotting, and the enzymatic processes involved in nucleotide synthesis are tested.
- The quizzes also cover genetic mutations and repair mechanisms, including the impact of mutations on splicing, nucleotide excision repair, and telomere maintenance.
- The quizzes test understanding of specific biochemical pathways, such as the urea cycle, heme biosynthesis, and DNA replication.
- Various biochemical terms and processes are mentioned, including polyubiquitination, ATP-dependent reactions, and the role of different enzymes in specific pathways.
- The text includes questions on the roles of specific proteins and enzymes in biochemical processes, such as thrombin, fibrinogen, and DNA polymerases.
- The quizzes cover the specific functions and mechanisms of various biochemical components, such as telomerase, histones, and nucleoside excision repair.
- The questions also address the impact of biochemical processes on human health, including diseases like Kwashiorkor, sickle cell anemia, and cancer.
- The quizzes cover key biochemical concepts and their applications, including the role of telomerase inhibitors as anti-cancer drugs and the use of dideoxyribonucleotides in DNA sequencing.
- The text provides a comprehensive review of biochemical knowledge and its relevance to various biological processes, genetic mutations, and disease states.
Biochemistry Practice Quiz Summaries
- The text consists of three practice quizzes covering topics such as protein turnover, plasma proteins, and nucleotide synthesis.
- The quizzes cover various biochemical processes including protein modification, blood clotting, and DNA synthesis.
- The quizzes include questions on specific enzymes and their functions, such as glutamate dehydrogenase, heme oxygenase, and thymidylate synthase.
- Important concepts such as the role of ubiquitin ligase in protein turnover, the action of plasma proteins in blood clotting, and the enzymatic processes involved in nucleotide synthesis are tested.
- The quizzes also cover genetic mutations and repair mechanisms, including the impact of mutations on splicing, nucleotide excision repair, and telomere maintenance.
- The quizzes test understanding of specific biochemical pathways, such as the urea cycle, heme biosynthesis, and DNA replication.
- Various biochemical terms and processes are mentioned, including polyubiquitination, ATP-dependent reactions, and the role of different enzymes in specific pathways.
- The text includes questions on the roles of specific proteins and enzymes in biochemical processes, such as thrombin, fibrinogen, and DNA polymerases.
- The quizzes cover the specific functions and mechanisms of various biochemical components, such as telomerase, histones, and nucleoside excision repair.
- The questions also address the impact of biochemical processes on human health, including diseases like Kwashiorkor, sickle cell anemia, and cancer.
- The quizzes cover key biochemical concepts and their applications, including the role of telomerase inhibitors as anti-cancer drugs and the use of dideoxyribonucleotides in DNA sequencing.
- The text provides a comprehensive review of biochemical knowledge and its relevance to various biological processes, genetic mutations, and disease states.
Test your understanding of biochemistry with these practice quizzes covering protein turnover, plasma proteins, nucleotide synthesis, and more. Explore concepts such as enzyme functions, genetic mutations, biochemical pathways, and their impact on human health. Brush up on terms like ubiquitin ligase, ATP-dependent reactions, and the roles of specific proteins and enzymes in biochemical processes.
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