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Biochemistry: Gluconeogenesis Pathway

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Questions and Answers

What is the primary role of the mitochondrial pyruvate transporter in the process described?

To export malate from the mitochondria to the cytosol

To transport pyruvate from the cytosol into the mitochondria (correct)

To convert pyruvate to oxaloacetate

To generate malate from oxaloacetate

What is the purpose of the reaction catalyzed by pyruvate carboxylase?

To generate NADH from mitochondrial NADH

To convert pyruvate to oxaloacetate (correct)

To transport malate from the mitochondria to the cytosol

To convert oxaloacetate to phosphoenolpyruvate

What is the purpose of the malate/α-ketoglutarate carrier in the process described?

To generate NADH from mitochondrial NADH

To convert oxaloacetate to phosphoenolpyruvate

To transport malate from the mitochondria to the cytosol (correct)

To transport pyruvate from the cytosol into the mitochondria

Which of the following is NOT a precursor for gluconeogenesis in the process described?

Glycerol Signup and view all the answers

What is the purpose of the reaction catalyzed by phosphoenolpyruvate carboxykinase?

To convert oxaloacetate to phosphoenolpyruvate Signup and view all the answers

Which of the following statements about gluconeogenesis is incorrect?

It is catalyzed by the same enzymes as glycolysis, but in the reverse direction. Signup and view all the answers

Which of the following is not a key enzyme specific to gluconeogenesis?

Aldolase Signup and view all the answers

In which of the following situations is gluconeogenesis required?

During prolonged starvation Signup and view all the answers

What is the first bypass reaction in gluconeogenesis?

Conversion of pyruvate to phosphoenolpyruvate Signup and view all the answers

Which of the following is not a reason for the continuous supply of glucose required by the body?

As a source of energy for adipose tissue Signup and view all the answers