Biochemistry Chapter 1: The Chemistry of Life

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Questions and Answers

What is the atomic number an indicator of?

  • Number of neutrons in an atom
  • Number of protons in an atom (correct)
  • Number of electrons in an atom
  • Mass of the atom

Isotopes of an element have the same number of protons but different numbers of electrons.

False (B)

How many protons are present in a carbon atom?

6

The mass number of an atom is the total number of protons and __________.

<p>neutrons</p> Signup and view all the answers

Match each isotope of carbon with its number of neutrons:

<p>Carbon-12 = 6 neutrons Carbon-13 = 7 neutrons Carbon-14 = 8 neutrons</p> Signup and view all the answers

Which of the following elements does not occur naturally as a single atom?

<p>Phosphorus (D)</p> Signup and view all the answers

What are the three naturally occurring isotopes of carbon?

<p>Carbon-12, Carbon-13, Carbon-14</p> Signup and view all the answers

The atomic masses of some elements are whole numbers.

<p>False (B)</p> Signup and view all the answers

Which of the following elements makes up roughly 99 percent of the mass of most cells?

<p>Hydrogen (D)</p> Signup and view all the answers

Carbon can form covalent bonds with up to six other atoms.

<p>False (B)</p> Signup and view all the answers

What term is used to describe molecules that contain carbon?

<p>Organic compounds</p> Signup and view all the answers

Water is classified as an ______ compound.

<p>inorganic</p> Signup and view all the answers

What role does carbon play in the diversity of life?

<p>Carbon can form a variety of geometrical structures. (B)</p> Signup and view all the answers

Match the following terms with their correct descriptions:

<p>Isomer = Molecules with the same molecular formula but different structures Covalent bond = A type of chemical bond where atoms share electrons Organic compound = A compound that contains carbon and hydrogen Inorganic compound = A compound that lacks carbon-hydrogen bonds</p> Signup and view all the answers

All organic compounds contain hydrogen atoms.

<p>False (B)</p> Signup and view all the answers

List one example of an inorganic compound.

<p>Carbon dioxide</p> Signup and view all the answers

What is the molecular formula for ethane?

<p>C2H6 (B)</p> Signup and view all the answers

Benzene is a simple organic molecule containing only carbon and oxygen.

<p>False (B)</p> Signup and view all the answers

What are hydrocarbons primarily used for?

<p>Fossil fuels for industrial activities</p> Signup and view all the answers

The molecular formula for methane is ______.

<p>CH4</p> Signup and view all the answers

Which structure represents the simplest tetrahedral geometry?

<p>Methane (A)</p> Signup and view all the answers

Match the following hydrocarbons with their molecular formulas:

<p>Methane = CH4 Ethane = C2H6 Benzene = C6H6</p> Signup and view all the answers

Hydrocarbons are components of living systems.

<p>False (B)</p> Signup and view all the answers

What is the structural formula of benzene represented as?

<p>C6H6</p> Signup and view all the answers

What happens when a chlorine atom gains an electron?

<p>It becomes a negative ion. (C)</p> Signup and view all the answers

Sodium chloride is formed when sodium reacts with chlorine.

<p>True (A)</p> Signup and view all the answers

How many protons does a chloride ion have?

<p>17</p> Signup and view all the answers

When sodium reacts with chlorine, sodium chloride is formed, represented as ______.

<p>NaCl</p> Signup and view all the answers

What is the role of ATP in living cells?

<p>It provides energy for cellular processes. (C)</p> Signup and view all the answers

Biologists are primarily concerned with the study of individual atoms.

<p>False (B)</p> Signup and view all the answers

What is true about the arrangement of ions in a sodium chloride crystal?

<p>Each sodium ion is surrounded by six chloride ions. (A)</p> Signup and view all the answers

Match the following ions with their characteristics:

<p>Na+ = Sodium ion with a positive charge Cl− = Chloride ion with a negative charge 17p = Number of protons in chlorine atom 18e− = Number of electrons in chloride ion</p> Signup and view all the answers

What is formed when bonds are created between atoms?

<p>Molecules</p> Signup and view all the answers

An atom becomes negatively charged when it loses an electron.

<p>False (B)</p> Signup and view all the answers

In cellular processes, __________ are involved in building and breaking down molecules.

<p>reactions</p> Signup and view all the answers

Match the following concepts with their descriptions:

<p>Bonds = Links between atoms Metabolic processes = Interactions that provide energy Electrons = Subatomic particles involved in bonding Cellular energy = Energy needed for life processes</p> Signup and view all the answers

What charge does a chloride ion have?

<p>negative</p> Signup and view all the answers

Why are large molecules essential for life?

<p>They perform critical biological functions. (C)</p> Signup and view all the answers

Chemical reactions in cells occur only during specific times and not continuously.

<p>False (B)</p> Signup and view all the answers

What must be known to understand biochemical processes within living organisms?

<p>How atoms combine to form molecules</p> Signup and view all the answers

What group did biologists refer to in relation to amino acids?

<p>R-group (B)</p> Signup and view all the answers

Thalidomide was initially found to be a safe drug for use during pregnancy.

<p>True (A)</p> Signup and view all the answers

What two groups are bonded to the central carbon of an amino acid?

<p>amine group and carboxyl group</p> Signup and view all the answers

Thalidomide is primarily used to treat __________.

<p>leprosy</p> Signup and view all the answers

Match the following effects of thalidomide with their descriptions:

<p>Induces sleep = Helps manage insomnia Reduces nausea = Alleviates feeling of sickness Anti-inflammatory agent = Reduces harmful immune reactions Treats autoimmune disorders = Helps conditions like rheumatoid arthritis</p> Signup and view all the answers

What led to the banning of thalidomide in 1964?

<p>It caused birth defects. (A)</p> Signup and view all the answers

Thalidomide has only negative effects on the human body.

<p>False (B)</p> Signup and view all the answers

What is the significance of the R-group in an amino acid?

<p>It determines the chemical properties of the amino acid.</p> Signup and view all the answers

Flashcards

Biochemistry

The study of how chemical reactions occur within living organisms, focusing on the interactions of atoms and molecules to support life processes.

Metabolic Processes

Chemical reactions that occur within a living organism to sustain life. These reactions involve the building up or breaking down of molecules.

Bond Formation

The process of forming new chemical bonds between atoms.

ATP (Adenosine Triphosphate)

A molecule that acts as an energy carrier within cells. It stores energy in its chemical bonds and releases it when needed.

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Anabolic Reactions

Chemical reactions that create larger molecules from smaller ones, usually requiring energy input.

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Catabolic Reactions

Chemical reactions that break down large molecules into smaller ones, usually releasing energy.

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Cellular Reactions

The chemical processes that take place to create or break down molecules within the cell.

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Cell Biology

The study of the structure and function of cells, the fundamental unit of life.

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Atomic Number

The number of protons in an atom's nucleus. It determines the element.

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Isotopes

Atoms of the same element with different numbers of neutrons.

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Mass Number

The total number of protons and neutrons in an atom's nucleus.

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Polyatomic Elements

Elements that exist naturally as molecules containing more than two atoms. Examples include phosphorus and sulfur.

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Isotope Example: Carbon-14

Atoms of a particular element that have a specific mass number, denoting the number of protons and neutrons in their nucleus.

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Atom

A fundamental building block of matter, composed of a dense, positively charged nucleus surrounded by negatively charged electrons.

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Electrons

Negatively charged particles that orbit the nucleus of an atom.

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Protons

Positively charged particles found in the nucleus of an atom.

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Cation

An atom with a net positive charge due to losing one or more electrons.

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Anion

An atom with a net negative charge due to gaining one or more electrons.

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Valence shell

The outermost electron shell of an atom, which participates in chemical bonding.

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Ionic bond

A chemical bond formed by the electrostatic attraction between oppositely charged ions.

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Ionic lattice

A three-dimensional arrangement of ions held together by ionic bonds.

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Valence

The number of electrons an atom needs to gain, lose, or share to achieve a stable electron configuration.

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Ionic compound

A substance formed by the ionic bonding of a metal and a non-metal.

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Ionization

The process of an atom gaining or losing electrons to achieve a stable electron configuration.

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What are organic compounds?

Molecules that contain carbon atoms are called organic compounds.

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What makes a compound inorganic?

A molecule that lacks carbon atoms is considered inorganic.

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How many bonds can carbon form?

Carbon can bond with up to 4 other atoms.

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What structures can carbon form?

The ability of carbon to bond with other carbon atoms allows for the formation of different structures, like straight chains, branched chains and rings.

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What atoms bond with carbon in biological systems?

Hydrogen, oxygen, nitrogen, phosphorus, sulfur, and carbon are the most common atoms involved in biological systems.

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What are functional groups?

Organic compounds that contain a specific group of atoms called functional groups have specific characteristics due to their unique properties.

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What are isomers?

Isomers are molecules with the same chemical formula but different structures.

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What are the four main types of macromolecules?

The four main types of macromolecules are carbohydrates, lipids, proteins and nucleic acids.

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Hydrocarbons

Simple organic molecules composed solely of carbon and hydrogen atoms.

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Methane

A hydrocarbon with the molecular formula CH4, having a tetrahedral structure. It's the simplest alkane and the main component of natural gas.

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Ethane

A hydrocarbon with the molecular formula C2H6, containing two carbon atoms linked by a single bond, and each carbon atom is bonded to three hydrogen atoms.

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Benzene

A hydrocarbon with the molecular formula C6H6, containing six carbon atoms arranged in a closed ring with alternating single and double bonds. It's a cyclic organic compound.

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Molecular Structure

The shape of a molecule determined by the arrangement of its atoms in space.

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Covalent Bond

A chemical bond where atoms share a pair of electrons.

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Solubility

The ability of a molecule to dissolve in a solvent, typically water.

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Diffusion

The movement of molecules from a region of high concentration to a region of low concentration.

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Carboxyl group

A functional group consisting of a carbon atom double-bonded to an oxygen atom and single-bonded to a hydroxyl group. It has the general formula COOH. It is acidic and can donate a proton (H+) to form a carboxylate ion.

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Amino group

A functional group consisting of a nitrogen atom bonded to two hydrogen atoms. It has the general formula NH2. It is basic and can accept a Proton (H+) to form an ammonium ion.

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R-group (Side Chain)

The unique chemical group attached to the alpha carbon atom of an amino acid. It determines the chemical properties of each amino acid.

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Alpha carbon

The carbon atom in an amino acid that is bonded to the amino group, carboxyl group, and the R-group.

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Amino acid

A molecule that serves as a building block for proteins. Each amino acid contains an amino group, a carboxyl group, an R-group, and a central carbon atom.

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Enzyme

A protein that acts as a catalyst to speed up chemical reactions in living organisms.

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Thalidomide

A powerful anti-inflammatory agent used to treat leprosy, rheumatoid arthritis, lupus, certain conditions associated with AIDS, and other diseases.

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TNF (Tumor Necrosis Factor)

A type of immune response that causes inflammation and can be damaging if excessive.

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Study Notes

Chapter 1: The Chemistry of Life

  • Biochemical processes involve millions of chemical reactions per second in cells, involving material transport, waste removal, and structural formation.
  • Metabolic processes involve electron interactions and bond formation/breaking to create or break down molecules.
  • Atoms combine to form molecules essential for life functions.
  • Elements like phosphorus and sulfur exist as molecules with more than two atoms.
  • Atomic number is the number of protons and is specific to each element.
  • Atoms of the same element with different numbers of neutrons are isotopes. Carbon-12, Carbon-13, and Carbon-14 are examples of carbon isotopes. They have the same number of protons (6) but different numbers of neutrons (6, 7, and 8 respectively).
  • Mass number is the sum of protons and neutrons in an atom's nucleus.
  • Atoms have equal numbers of electrons and protons, thus no overall charge (neutral).
  • Isotopes have different mass numbers.
  • Atomic masses of elements prevalent in living organisms are presented in Table 1.1.
  • An atom gains or loses electrons to become an ion (e.g., Cl- for chlorine and Na+ for sodium).
  • Ionic bonds form when oppositely charged ions attract (e.g., sodium chloride (NaCl)).
  • An ionic bond arrangement forms a three-dimensional lattice in compounds like sodium chloride.

Chapter 2: Enzymes and Energy

  • This chapter explores how cell biology relates to lifestyle.

Chapter 3: Cellular Energy

  • This chapter examines how organisms acquire energy for life processes.

Unit Investigation

  • Unit investigation materials can be planned in advance.
  • Students should look ahead to pages 98-99 for investigation details.
  • Ideas and materials from the unit can be incorporated into experimental designs.

Biological Macromolecules and Their Subunits

  • Organic compounds are mainly composed of carbon, hydrogen, and often oxygen.
  • Pure carbon and carbon compounds without hydrogen (e.g., CO2, CaCO3) are considered inorganic.
  • Many organic compounds contain hydrogen, oxygen, carbon, nitrogen, phosphorus, and sulfur.
  • Water (an inorganic compound) is crucial for dissolving and transporting substances within and between cells.
  • Carbon's ability to bond with other carbon atoms creates different structures (straight chains, branched chains, and rings).
  • Hydrocarbons are examples of carbon compounds, but not part of living systems. Methane, ethane, and benzene are simple examples.
  • Macromolecules are formed from smaller subunits (e.g. amino acids form proteins)
  • Functional groups influence molecule properties.
  • Isomers have the same molecular formula but different structures.

Thalidomide Dilemma

  • Thalidomide, a drug once used as a sleeping pill and morning sickness remedy, caused birth defects in children of mothers who took it.
  • Tests showed thalidomide to be non-toxic.
  • The drug was banned in 1964.
  • Thalidomide has other effects, including anti-inflammatory properties and moderation of immune system reactions.
  • It's now used to treat leprosy, rheumatoid arthritis, lupus, conditions associated with AIDS, and other diseases.
  • Tumor necrosis factor (TNF) is a chemical used by blood cells for immune response.

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