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Bioceramics: Properties and Advantages
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Bioceramics: Properties and Advantages

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Questions and Answers

What is the primary purpose of a biomaterial?

  • To evaluate, treat, or replace any tissue or organ in the body (correct)
  • To create non-viable materials
  • To interface with mechanical systems
  • To create artificial joints only
  • What type of material can be a biomaterial?

  • Either natural or synthetic materials (correct)
  • Only synthetic materials
  • Only natural materials
  • Neither natural nor synthetic materials
  • What is a biomaterial used for?

  • To create non-viable materials for medical devices
  • To interact with mechanical systems
  • To create artificial organs only
  • To evaluate, treat, augment, or replace any tissue, organ or function of the body (correct)
  • What is the key characteristic of a biomaterial according to the Merriam-Webster Dictionary?

    <p>It is suitable for introduction into living tissue</p> Signup and view all the answers

    What is the common thread among different definitions of biomaterials?

    <p>The material must interact with biological systems</p> Signup and view all the answers

    What is one of the applications of biomaterials in the skeletal system?

    <p>Bone plate</p> Signup and view all the answers

    Which material is used in dental implants?

    <p>Titanium</p> Signup and view all the answers

    What is one of the applications of biomaterials in the cardiovascular system?

    <p>Heart valve</p> Signup and view all the answers

    Which material is used in cochlear replacement?

    <p>Silicone rubber</p> Signup and view all the answers

    What is one of the types of materials used in biomaterials?

    <p>Teflon</p> Signup and view all the answers

    What is one of the applications of biomaterials in the senses?

    <p>Contact lens</p> Signup and view all the answers

    What is a major disadvantage of bioceramic materials?

    <p>Low strength in tension</p> Signup and view all the answers

    What is a key requirement for a biomaterial to be considered biocompatible?

    <p>It must not cause any undesirable biological effects</p> Signup and view all the answers

    What is the term used to describe the ability of a biomaterial to resist corrosion and wear?

    <p>Wear and corrosion resistance</p> Signup and view all the answers

    What is the purpose of surface modification in biomaterials?

    <p>To change the material's surface properties</p> Signup and view all the answers

    What is the term used to describe the study of the surface properties of materials?

    <p>Surface analysis</p> Signup and view all the answers

    What type of bond is typically found in ceramic materials?

    <p>Ionic bond</p> Signup and view all the answers

    What is the meaning of the Greek word 'keramos'?

    <p>The art and science of making and using solid articles formed by the action of heat on earthy raw materials.</p> Signup and view all the answers

    What percentage of the Earth's crust is composed of oxygen?

    <p>50%</p> Signup and view all the answers

    What is a significant advantage of ceramic materials in orthopedic and dental applications?

    <p>High wear resistance and high modulus</p> Signup and view all the answers

    What type of ceramic materials exhibit lower strengths but are useful as coatings for metallic implants?

    <p>Porous ceramic materials</p> Signup and view all the answers

    What is a disadvantage of ceramic materials?

    <p>Brittleness</p> Signup and view all the answers

    What is a common application of ceramic materials?

    <p>All of the above</p> Signup and view all the answers

    What is a characteristic of bioceramics?

    <p>Establishing bonds with bone tissue</p> Signup and view all the answers

    What is a type of polymer?

    <p>All of the above</p> Signup and view all the answers

    What is a benefit of composite materials?

    <p>Combining the strengths of different materials</p> Signup and view all the answers

    What is a complication that can occur from the use of metals in orthopedic applications?

    <p>Stress shielding</p> Signup and view all the answers

    What is the primary function of a bioactive material in the body?

    <p>To recruit specific interactions between the material and surrounding tissue</p> Signup and view all the answers

    What is the purpose of the porous coating of Hydroxyapatite (HA) on total hip implants?

    <p>To aid in the fixation of the implant in the body</p> Signup and view all the answers

    What is the trend in healthcare technology?

    <p>From bio-inert to second-generation materials</p> Signup and view all the answers

    What is the expected outcome of tissue engineering, microsystems and nanotechnology?

    <p>Addressing many needs in healthcare</p> Signup and view all the answers

    What is the difference between bioactive and biocompatible materials?

    <p>Biocompatible materials aim to minimize interactions with the body, while bioactive materials aim to maximize interactions</p> Signup and view all the answers

    What is the goal of 'second-generation' materials?

    <p>To correct pathologies and maintain physiological function</p> Signup and view all the answers

    Study Notes

    Bioactive Materials

    • Bioactive materials play a more aggressive role in the body, recruiting specific interactions between the material and surrounding tissue.
    • Encourage tissue integration to aid in the fixation of an implant in the body.
    • Examples: porous coating of Hydroxyapatite (HA) to help permanently stabilize the stem of the implant in the bone.

    Biomaterials

    • A material intended to interface with biological systems to evaluate, treat, augment, or replace any tissue, organ, or function of the body.
    • Can be natural or synthetic.
    • Examples: metals, ceramics, polymers, and composites.

    Biomaterials Properties

    • Compressive strength
    • Tensile strength
    • Bending strength
    • E-Modulus
    • Coefficient of thermal expansion
    • Coefficient of thermal conductivity
    • Surface tension
    • Hardness and density
    • Hydrophobic/philic
    • Water sorption/solubility
    • Surface friction
    • Creep
    • Bonding properties
    • Surface modification (treatment)

    Surface Properties of Materials

    • Contact angle (Hydrophilic & Hydrophobic)
    • ESCA & SIMS (surface chemical analysis)
    • SEM (Surface morphology)
    • Deterioration of Biomaterials: corrosion, degradation, calcification, mechanical, and combined loading.

    General Criteria for Materials Selection

    • Mechanical and chemical properties
    • No undesirable biological effects (carcinogenic, toxic, allergenic, or immunogenic)
    • Possible to process, fabricate, and sterilize with good reproducibility
    • Acceptable cost/benefit ratio

    Requirements of Biomaterials

    • Inert or specifically interactive
    • Biocompatible
    • Mechanically and chemically stable or biodegradable
    • Processable (for manufacturability)
    • Non-thrombogenic (if blood-contacting)
    • Sterilizable

    Ceramic Biomaterials

    • Inorganic compounds that contain metallic and non-metallic elements
    • Derived from the Greek word "keramos" meaning the art and science of making and using solid articles formed by the action of heat on earthy raw materials
    • Advantages: inert in body, high wear resistance, high modulus, and compressive strength, fine esthetic properties for dental applications
    • Disadvantages: brittle, low tensile strength, poor fatigue resistance

    Applications of Ceramic Biomaterials

    • Femoral heads and cup inserts for ceramic on polyethylene
    • Ceramic on ceramic hip replacement bearings
    • Knee prostheses
    • Spinal fusion devices
    • Orthopedic instrumentation
    • Dental crowns, bridges, and implants
    • Inner ear implants (cochlear implants)
    • Drug delivery devices

    Polymeric Biomaterials

    • Consist of small repeating units strung together in long chains
    • Flexible structure of polymers has enabled their use in various applications
    • Can be hydrophilic, hydrophobic, biostable, biodegradable, natural, or synthetic
    • Highly processable

    Composite Biomaterials

    • Incorporate the desired characteristics of different materials to meet the stringent demands of living tissue
    • Combine strength and flexibility by reinforcing a relatively flexible material with a harder, stronger one
    • In some cases, one or more of these materials may be degradable to encourage tissue integration

    Metallic Biomaterials

    • High strength
    • Fatigue resistance
    • Wear resistance
    • Easy fabrication
    • Easy to sterilize
    • Shape memory
    • High modulus
    • Disadvantages: corrosion, metal ion sensitivity, and toxicity, metallic looking

    Applications of Biomaterials

    • Skeletal system: joint replacement (hip, knee), bone plate, bone cement, artificial tendon, and ligament
    • Cardiovascular system: blood vessel prosthesis, heart valve, and catheter
    • Organs: artificial heart, skin repair template, artificial kidney, and heart-lung machine
    • Senses: cochlear replacement, intraocular lens, contact lens, and corneal bandage

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