17 Questions
What is the main function of the Sphincter of Oddi in relation to bile?
It relaxes to allow bile flow into the duodenum.
Which process mainly occurs in the lumen of the small intestine for fat assimilation?
Esterification to form triglycerides
What happens to ~5% of conjugated bile acids in the enterohepatic circulation?
They are lost in the feces.
Which molecule is responsible for delivering fat to tissues via lymphatics for utilization?
Chylomicron
How do bile acids mainly assist in the assimilation of fat?
By forming micelles with fatty acids and monoglycerides.
What is the primary function of the acinus in the liver?
Bile acid synthesis
Which amino acid is used for conjugation with primary bile acids in dogs?
Taurine
Which part of the gastrointestinal tract plays a significant role in reabsorbing 95% of conjugated bile acids?
Ileum
What is the rate-limiting step in the synthesis of primary bile acids?
7-β hydroxylation
Where are bile acids stored before being released into the intestine for digestion?
Gallbladder
Which species requires Taurine as an essential amino acid for bile acid conjugation?
Cats
What is the role of cholecystokinin (CCK) in gallbladder contraction?
Mediates the contraction of the gallbladder
In which species is the sphincter of Oddi less well-defined and constantly secreting bile into the intestinal tract?
Ruminants
What is a key difference in bile acid metabolism between dogs/cats and ruminants/pigs/horses?
Ruminants/pigs/horses have a closed sphincter of Oddi between meals
Which animal species does not have a gallbladder and has a weak sphincter of Oddi?
Horses
What is the significance of bile acids in systemic circulation for liver function?
Increased bile acids in systemic circulation can signal impaired liver function
What is the effect of special considerations like fasting on bile samples for liver function tests?
Fasting can decrease bile production in horses, leading to unreliable results
Learn about the storage and release of bile within the gallbladder, including the role of the gallbladder epithelium in altering bile composition. Understand how conjugated bile acids are transported and the influence of CCK on the sphincter of Oddi.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
