15 Questions
Match the antibiotic with its mechanism of action:
Tetracycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Neomycin = Acts directly on the bacterial ribosome to inhibit the initiation of protein synthesis Bacitracin = Cell wall synthesis inhibitors, against gram-positives Vancomycin = Prevents cross-linking of peptidoglycan cell wall
Match the antibiotic with its source:
Tetracycline = Synthetic or semisynthetic compounds Neomycin = Isolated from Streptomyces Bacitracin = Polypeptide antibiotics Vancomycin = Glycopeptide antibiotic
Match the antibiotic with its target bacteria:
Tetracycline = Aerobic, gram-negative bacteria Neomycin = Aerobic, gram-negative bacilli Bacitracin = Gram-positives Vancomycin = Antibiotic-resistant S.aureus
Match the antibiotic with its primary usage:
Tetracycline = Broad-spectrum antibiotic Neomycin = Potent bactericidal antibiotic Bacitracin = Topical application, against gram-positives Vancomycin = Important 'last line' against antibiotic-resistant S.aureus
Match the antibiotic with its route of administration:
Tetracycline = Well absorbed orally Neomycin = Cannot safely be used systemically Bacitracin = Topical application Vancomycin = Varies, including intravenous administration
Match the tetracycline antibiotic with its mechanism of action:
Doxycycline = Inhibits protein synthesis by binding to the 30S ribosomal subunit Minocycline = Blocks protein synthesis by binding to the 30S ribosomal subunit Tetracycline = Interferes with protein synthesis by binding to the 30S ribosomal subunit Demeclocycline = Disrupts protein production by binding to the 30S ribosomal subunit
Match the tetracycline antibiotic with its primary usage:
Doxycycline = Treatment of acne and respiratory tract infections Minocycline = Prescribed for acne and bacterial infections Tetracycline = Used for urinary tract infections and gonorrhea Demeclocycline = Treatment of Lyme disease and pneumonia
Match the tetracycline antibiotic with its target bacteria:
Doxycycline = Effective against Chlamydia and Mycoplasma species Minocycline = Targets Staphylococcus aureus and Streptococcus pneumoniae Tetracycline = Acts on Escherichia coli and Haemophilus influenzae Demeclocycline = Targets Neisseria gonorrhoeae and Rickettsia
Match the tetracycline antibiotic with its mechanism of action:
Tetracycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Doxycycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Minocycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Glycylcycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome
Match the tetracycline antibiotic with its primary usage:
Tetracycline = Treatment of bacterial diseases Doxycycline = Treatment of bacterial diseases Minocycline = Treatment of bacterial diseases Glycylcycline = Treatment of bacterial diseases
Match the tetracycline antibiotic with its route of administration:
Tetracycline = Orally absorbed well Doxycycline = Orally absorbed well Minocycline = Orally absorbed well Glycylcycline = Orally absorbed well
Match the antibiotic with its primary usage:
Clavulanic acid = Beta-lactamase inhibitor Amoxicillin = Combined with clavulanic acid as clavamox or augmentin Cephalosporins = Used as penicillin substitutes against Gram-negative bacteria and in surgical prophylaxis Tetracyclines = Broad-spectrum antibiotics with a wide range of activity against both Gram-positive and Gram-negative bacteria
Match the antibiotic with its mechanism of action:
Clavulanic acid = Irreversible, 'suicide' inhibitor of beta-lactamase Amoxicillin = Inactivation by bacterial beta-lactamases Cephalosporins = Prevents cell wall synthesis by binding to penicillin binding proteins (PBPs) Tetracyclines = Bacteriostatic compounds
Match the antibiotic with its target bacteria:
Clavulanic acid = Bacteria that produce beta-lactamase enzymes Amoxicillin = Wide range of bacteria including Gram-positive and Gram-negative bacteria Cephalosporins = Gram-negative bacteria and some resistance to beta-lactamases from S.aureus Tetracyclines = Broad range including both Gram-positive and Gram-negative bacteria
Match the antibiotic with its resistance pattern:
Clavulanic acid = Overcoming resistance in bacteria that produce beta-lactamase enzymes Amoxicillin = Subject to degradation by some bacterial beta-lactamases Cephalosporins = Resistant to beta-lactamases from S.aureus Tetracyclines = Pseudomonas aeruginosa is less sensitive but generally susceptible to tetracycline concentrations
Test your knowledge about beta-lactamase inhibitors such as clavulanic acid and the pharmacological relationship and uses of Cephalosporins. Learn about the combination of clavulanic acid with antibiotics like amoxicillin to overcome bacterial resistance.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
