Beta-Lactamase Inhibitors and Cephalosporins Quiz

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Match the antibiotic with its mechanism of action:

Tetracycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Neomycin = Acts directly on the bacterial ribosome to inhibit the initiation of protein synthesis Bacitracin = Cell wall synthesis inhibitors, against gram-positives Vancomycin = Prevents cross-linking of peptidoglycan cell wall

Match the antibiotic with its source:

Tetracycline = Synthetic or semisynthetic compounds Neomycin = Isolated from Streptomyces Bacitracin = Polypeptide antibiotics Vancomycin = Glycopeptide antibiotic

Match the antibiotic with its target bacteria:

Tetracycline = Aerobic, gram-negative bacteria Neomycin = Aerobic, gram-negative bacilli Bacitracin = Gram-positives Vancomycin = Antibiotic-resistant S.aureus

Match the antibiotic with its primary usage:

Tetracycline = Broad-spectrum antibiotic Neomycin = Potent bactericidal antibiotic Bacitracin = Topical application, against gram-positives Vancomycin = Important 'last line' against antibiotic-resistant S.aureus Signup and view all the answers

Match the antibiotic with its route of administration:

Tetracycline = Well absorbed orally Neomycin = Cannot safely be used systemically Bacitracin = Topical application Vancomycin = Varies, including intravenous administration Signup and view all the answers

Match the tetracycline antibiotic with its mechanism of action:

Doxycycline = Inhibits protein synthesis by binding to the 30S ribosomal subunit Minocycline = Blocks protein synthesis by binding to the 30S ribosomal subunit Tetracycline = Interferes with protein synthesis by binding to the 30S ribosomal subunit Demeclocycline = Disrupts protein production by binding to the 30S ribosomal subunit Signup and view all the answers

Match the tetracycline antibiotic with its primary usage:

Doxycycline = Treatment of acne and respiratory tract infections Minocycline = Prescribed for acne and bacterial infections Tetracycline = Used for urinary tract infections and gonorrhea Demeclocycline = Treatment of Lyme disease and pneumonia Signup and view all the answers

Match the tetracycline antibiotic with its target bacteria:

Doxycycline = Effective against Chlamydia and Mycoplasma species Minocycline = Targets Staphylococcus aureus and Streptococcus pneumoniae Tetracycline = Acts on Escherichia coli and Haemophilus influenzae Demeclocycline = Targets Neisseria gonorrhoeae and Rickettsia Signup and view all the answers

Match the tetracycline antibiotic with its mechanism of action:

Tetracycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Doxycycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Minocycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Glycylcycline = Inhibits protein synthesis by blocking the binding of aminoacyl tRNA to the A site on the ribosome Signup and view all the answers

Match the tetracycline antibiotic with its primary usage:

Tetracycline = Treatment of bacterial diseases Doxycycline = Treatment of bacterial diseases Minocycline = Treatment of bacterial diseases Glycylcycline = Treatment of bacterial diseases Signup and view all the answers

Match the tetracycline antibiotic with its route of administration:

Tetracycline = Orally absorbed well Doxycycline = Orally absorbed well Minocycline = Orally absorbed well Glycylcycline = Orally absorbed well Signup and view all the answers

Match the antibiotic with its primary usage:

Clavulanic acid = Beta-lactamase inhibitor Amoxicillin = Combined with clavulanic acid as clavamox or augmentin Cephalosporins = Used as penicillin substitutes against Gram-negative bacteria and in surgical prophylaxis Tetracyclines = Broad-spectrum antibiotics with a wide range of activity against both Gram-positive and Gram-negative bacteria Signup and view all the answers

Match the antibiotic with its mechanism of action:

Clavulanic acid = Irreversible, 'suicide' inhibitor of beta-lactamase Amoxicillin = Inactivation by bacterial beta-lactamases Cephalosporins = Prevents cell wall synthesis by binding to penicillin binding proteins (PBPs) Tetracyclines = Bacteriostatic compounds Signup and view all the answers

Match the antibiotic with its target bacteria:

Clavulanic acid = Bacteria that produce beta-lactamase enzymes Amoxicillin = Wide range of bacteria including Gram-positive and Gram-negative bacteria Cephalosporins = Gram-negative bacteria and some resistance to beta-lactamases from S.aureus Tetracyclines = Broad range including both Gram-positive and Gram-negative bacteria Signup and view all the answers

Match the antibiotic with its resistance pattern:

Clavulanic acid = Overcoming resistance in bacteria that produce beta-lactamase enzymes Amoxicillin = Subject to degradation by some bacterial beta-lactamases Cephalosporins = Resistant to beta-lactamases from S.aureus Tetracyclines = Pseudomonas aeruginosa is less sensitive but generally susceptible to tetracycline concentrations Signup and view all the answers