18 Questions
What is the mechanism of action of benzodiazepines on GABA receptors?
Enhancing the effect of GABA
Which of the following best describes the drug interactions of benzodiazepines?
Enhanced effects when taken with CNS depressants
Which adverse reaction is NOT commonly associated with benzodiazepines?
Increased appetite
What could be the consequence of taking benzodiazepines with inhibitors of the CYP3A system?
Increased risk of toxicity
What are some potential effects of benzodiazepines on sleep according to the text?
Reduced level of consciousness
Which statement accurately describes the potential for dependence related to benzodiazepines?
Potential for abuse, tolerance, and physical dependence
Which stage of sleep do benzodiazepines decrease the amount of time spent in?
Stage 3 and 4
What is the advantage of benzodiazepines over barbiturates in terms of REM sleep?
Benzodiazepines do not affect REM sleep
What neurotransmitter is involved in the mechanism of action of benzodiazepines?
GABA
How do benzodiazepines affect the duration of rapid-eye-movement (REM) sleep?
Have no effect on REM sleep duration
What is the primary clinical indication for benzodiazepines?
Relaxing the patient during surgery
Which stage of sleep resembles brain activity when awake and is characterized by relaxed muscles and rapid eye movements?
REM sleep
Which of the following is a key consideration when prescribing benzodiazepines to elderly patients?
Using those with long half-life or active metabolites
What is the major pharmacologic action of barbiturates?
Reduce CNS alertness
Which part of the brain is particularly sensitive to the effects of barbiturates?
Reticular activating system (RAS)
What is the primary route of excretion for barbiturates?
Kidneys
Which CNS function is altered by barbiturates to induce drowsiness?
Cerebral function
What is a potential adverse effect of high doses of barbiturates?
Respiratory depression
Explore how benzodiazepines interact with receptors to enhance the effect of GABA and slow down nerve impulses. Learn about the drug interactions and effects on the central nervous system.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
