Benzodiazepines and GABA Receptors

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Questions and Answers

Which tissue acts as a reservoir for lipophilic benzodiazepines?

  • Muscle tissue
  • Bone tissue
  • Nervous tissue
  • Adipose tissue (correct)

What effect do benzodiazepines have on GABA receptor-mediated neurotransmission?

  • They have no impact on neurotransmission
  • They enhance excitatory neurotransmission
  • They potentiate the inhibition of neurotransmission (correct)
  • They completely block neurotransmission

Which route of administration results in erratic and slow absorption of benzodiazepines?

  • Oral
  • Nasal
  • IV (Intravenous) (correct)
  • Sublingual

Which benzodiazepine is classified as having a long duration of action?

<p>Flurazepam (D)</p> Signup and view all the answers

In what way do benzodiazepines affect the GABA receptor channel?

<p>They open the chloride channel when GABA is bound, leading to neuron hyperpolarization (D)</p> Signup and view all the answers

Flashcards

Lipophilic Benzodiazepine Reservoir

Adipose tissue acts as a reservoir for these drugs due to their fat-soluble properties.

Benzodiazepine Effect on GABA

Benzodiazepines enhance the effect of GABA, leading to increased inhibition of nerve signals.

GABA Receptor Channel Effect

Opening of this channel leads to hyperpolarization of the neuron (Reduced excitability).

Flurazepam Duration

This drug is used to treat insomnia because it stays in the system longer.

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