Benzodiazepine Withdrawal Symptoms and Management

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39 Questions

Which neurotransmitter is typically decreased in patients with anxiety disorders?

Serotonin

What is a common side effect associated with benzodiazepines?

Respiratory depression

In anxiety disorders, what brain circuit is associated with fear, panic, and phobia?

Amygdala-centered circuit

Which medical condition may precipitate anxiety in some individuals?

Hypothyroidism

What is the primary role of SSRIs in the treatment of anxiety disorders?

Blocking the reuptake of serotonin

Which system in the body shows hyperactivity in individuals with anxiety disorders?

Autonomic nervous system

What is the first-line treatment for chronic anxiety, generalized anxiety disorder (GAD), and panic disorder?

Selective serotonin reuptake inhibitors (SSRI)

Which of the following medical conditions may precipitate anxiety according to the text?

Thyroid disease

What is the common MOA of benzodiazepines?

Potentiation of GABA effects

What is a potential risk associated with benzodiazepine use in elderly patients?

Increased fall risk

What is a common side effect of benzodiazepines mentioned in the text?

Daytime drowsiness

When are benzodiazepines suggested to be useful in anxiety disorders according to the text?

During SSRI/SNRI initiation to rapidly reduce anxiety

Which symptom is not associated with benzodiazepine withdrawal?

Muscle weakness

Which benzodiazepine is commonly used in the treatment of seizures?

Clonazepam (Klonopin)

What is a side effect associated with long-term benzodiazepine use?

Rebound insomnia

Which benzodiazepine has a high potential for abuse due to its short half-life?

Alprazolam (Xanax)

Which benzodiazepine is recommended for use in cases of severe alcohol withdrawal?

Lorazepam (Ativan)

What is a key takeaway regarding benzodiazepines and their usage?

"Easy to start, hard to stop"

Which type of medication has the highest anticholinergic effect?

TCAs

What is a known limitation of benzodiazepine treatment?

Rebound insomnia

Which non-benzodiazepine anxiolytic has a low potential for abuse/addiction?

Buspirone

Which anxiolytic has a slower onset of action compared to typical benzodiazepines?

Buspirone

Why is Propranolol rarely used as an anxiolytic?

Lethality of overdose

Which medical condition is a contraindication for using Propranolol as an anxiolytic?

Asthma

What is the first-line pharmacologic management for agoraphobia?

Lexapro

Which antihistamine has a fairly wide dosage range and can be sedating?

Hydroxyzine

What is the primary reason for initially using benzodiazepines in panic attacks?

Rapid relief of symptoms

Which anticonvulsant has the most street value from the mentioned list?

Gabapentin

What is a common side effect of hydroxyzine mentioned in the text?

Paradoxical response

Which class of medications can be considered as augmentation therapy with buspirone (Buspar) for generalized anxiety disorder?

Benzodiazepines

What is considered the first-line treatment for anxiety disorders?

SSRI or SNRIs

Which medication is FDA approved for Panic Disorder and Social Phobia?

Alprazolam (Xanax)

What can be used as an adjunct to mainline treatments for anxiety, but should be used with caution and only short-term?

Benzodiazepines

In severe cases of Obsessive Compulsive Disorder (OCD), which medication class can be augmented to the treatment?

Atypical antipsychotics

What are the symptoms of SSRI discontinuation syndrome known as FINISH?

Flu-like symptoms, insomnia, imbalance

Which medication can be considered when a patient experiences SSRI-related sexual dysfunction?

Wellbutrin

For specific phobias, which treatment modality is often recommended along with medication?

Cognitive Behavioral Therapy (CBT)

"Fear of scrutiny by others or fear of acting in a humiliating or embarrassing way" is characteristic of which condition?

Social Phobia

Which type of medication can be considered as second-line treatment for Obsessive Compulsive Disorder?

TCAs

Learn about the symptoms of benzodiazepine withdrawal, which can be similar to alcohol withdrawal, including insomnia, anxiety, hand tremors, and more. Understand the potential life-threatening risks of abrupt abstinence and the management strategies such as tapering the dose gradually.

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