Benzathine Penicillin G and Gram-Positive Bacteria Quiz
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Questions and Answers

Which antibiotic is NOT cross-allergenic to beta-lactams?

  • Aztreonam (correct)
  • Meropenem
  • Vancomycin
  • Imipenem

    • Which antibiotic is MOST IMPORTANT for the treatment of MRSA?

  • Ceftriaxone
  • Vancomycin (correct)
  • Aztreonam
  • Imipenem

    • Which antibiotic is synergistic with aminoglycosides and inhibits cell wall synthesis?

  • Vancomycin (correct)
  • Meropenem
  • Imipenem
  • Ceftriaxone

    • Which antibiotic has a broad spectrum and is commonly used for empiric therapy?

    <p>Ceftriaxone</p> Signup and view all the answers

    Which antibiotic has reduced renal function as a contraindication?

    <p>Imipenem</p> Signup and view all the answers

    Which antibiotic is only effective against aerobic Gram-negative rods?

    <p>Aztreonam</p> Signup and view all the answers

    Which antibiotic is IV administration specific?

    <p>Ceftriaxone</p> Signup and view all the answers

    Which antibiotic inhibits the synthesis of cell membrane phospholipids?

    <p>Vancomycin</p> Signup and view all the answers

    Which one of the following is the drug of choice for all stages of syphilis caused by Treponema Pallidum?

    <p>Bicillin L-A</p> Signup and view all the answers

    Which penicillin is resistant to staphylococcal penicillinase (beta-lactamase)?

    <p>Nafcillin</p> Signup and view all the answers

    Which extended-spectrum penicillin has the highest oral bioavailability?

    <p>Amoxicillin</p> Signup and view all the answers

    Which cephalosporin is the first-line treatment for Neisseria gonorrhoeae infections?

    <p>Ceftriaxone</p> Signup and view all the answers

    Which cephalosporin generation has the broadest spectrum of activity, including coverage of Pseudomonas aeruginosa?

    <p>4th generation</p> Signup and view all the answers

    Which cephalosporin is the only beta-lactam antibiotic that can treat methicillin-resistant Staphylococcus aureus (MRSA)?

    <p>Ceftaroline fosamil</p> Signup and view all the answers

    Which mechanism of resistance to beta-lactam antibiotics is the most common?

    <p>Inactivation by beta-lactamase</p> Signup and view all the answers

    Which of the following is NOT a true statement about the interactions of beta-lactam antibiotics?

    <p>Probenecid can be safely used in patients with reduced renal function.</p> Signup and view all the answers

    Which of the following bacteria is NOT susceptible to penicillin G?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    Which of the following is the primary mechanism of action of beta-lactam antibiotics?

    <p>Inhibition of cell wall synthesis</p> Signup and view all the answers

    Which of the following antibiotics is considered an antipseudomonal penicillin?

    <p>Piperacillin</p> Signup and view all the answers

    Which of the following infections is NOT typically treated with penicillin G?

    <p>Urinary tract infection caused by Escherichia coli</p> Signup and view all the answers

    Which of the following statements about the side effects of penicillins is TRUE?

    <p>Penicillins can cause interstitial nephritis, a form of kidney injury.</p> Signup and view all the answers

    Which of the following statements about the pharmacokinetics of beta-lactam antibiotics is correct?

    <p>Beta-lactams exhibit time-dependent killing.</p> Signup and view all the answers

    Which of the following statements about the use of benzathine penicillin G is TRUE?

    <p>It is used for the treatment of syphilis.</p> Signup and view all the answers

    Which of the following statements about the spectrum of activity of penicillin V is correct?

    <p>It is only effective against streptococci and pneumococci.</p> Signup and view all the answers

    Which mechanism of resistance to vancomycin renders the bacteria completely resistant to any amount of vancomycin?

    <p>Modification of the vancomycin binding site</p> Signup and view all the answers

    Which of the following is NOT a common unintended effect of daptomycin?

    <p>Hypersensitivity reactions</p> Signup and view all the answers

    Which of the following is the primary reason why tetracyclines are contraindicated in pregnant women and children under 8 years old?

    <p>Binding to newly formed teeth and bones</p> Signup and view all the answers

    Which macrolide antibiotic has the longest half-life, allowing for a shorter course of treatment?

    <p>Azithromycin</p> Signup and view all the answers

    Which aminoglycoside antibiotic has the broadest spectrum of activity and is resistant to the main mechanism of resistance, enzymatic inactivation?

    <p>Amikacin</p> Signup and view all the answers

    Why are aminoglycosides bactericidal and can be used synergistically with cell wall inhibitors, while other antibiotics like tetracyclines and macrolides are bacteriostatic and cannot be used with cell wall inhibitors?

    <p>Aminoglycosides cause misreading of mRNA, leading to cell death, while tetracyclines and macrolides only inhibit protein synthesis.</p> Signup and view all the answers

    Which macrolide antibiotic is commonly used to treat Helicobacter pylori infections?

    <p>Clarithromycin</p> Signup and view all the answers

    Which tetracycline antibiotic is considered to have the most favorable pharmacokinetic properties and is safe to use in patients with reduced renal function?

    <p>Doxycycline</p> Signup and view all the answers

    Which of the following statements about penicillin G is correct?

    <p>Penicillin V is the oral form of penicillin G used to treat streptococcal and pneumococcal infections.</p> Signup and view all the answers

    Which of the following infections can be treated with antistaphylococcal penicillins like nafcillin or oxacillin?

    <p>Skin and soft tissue infections caused by staphylococci and streptococci</p> Signup and view all the answers

    Which of the following statements about extended-spectrum penicillins (aminopenicillins) is correct?

    <p>They have an amino group in their structure, which increases their activity against Gram-negative bacteria.</p> Signup and view all the answers

    Which of the following statements about the use of ampicillin is correct?

    <p>It is the drug of choice for treating meningitis caused by Streptococcus pneumoniae, Neisseria meningitidis, and Listeria monocytogenes.</p> Signup and view all the answers

    Which of the following statements about penicillin G and its derivatives is correct?

    <p>They can cross the blood-brain barrier and are used to treat meningitis caused by Neisseria meningitidis and Treponema pallidum.</p> Signup and view all the answers

    Which of the following statements about the spectrum of activity of penicillins is correct?

    <p>Penicillin V is effective against streptococci and pneumococci, which are common causes of respiratory tract infections.</p> Signup and view all the answers

    Which of the following statements about the use of amoxicillin is correct?

    <p>It is used to treat peptic ulcers caused by Helicobacter pylori and is the drug of choice for otitis media due to its activity against common respiratory pathogens.</p> Signup and view all the answers

    Which of the following statements about the use of penicillins in meningitis treatment is correct?

    <p>Ampicillin is the drug of choice for treating meningitis caused by Neisseria meningitidis and Haemophilus influenzae.</p> Signup and view all the answers

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