Benefits of Long-Acting Injections and Acute Agitation Interventions
74 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is a key diagnostic requirement for schizophrenia according to DSM-5?

  • Having 2 of the specified symptoms for a 1-month period (correct)
  • Displaying negative symptoms intermittently
  • Presence of delusions only
  • Experiencing hallucinations for at least 6 months

    • Which of the following substances is known to exacerbate psychosis?

  • Ketamine (correct)
  • Antibiotics
  • Caffeine
  • Antihistamines

    • What are some medical conditions that can present with psychosis?

  • Parkinson's disease (correct)
  • Diabetes
  • Arthritis
  • Asthma

    • What is the main concern with ziprasidone use?

    <p>QTc prolongation</p> Signup and view all the answers

    Which antipsychotic causes a metallic taste as a side effect?

    <p>Asenapine</p> Signup and view all the answers

    What is the recommended treatment for treatment-resistant schizophrenia?

    <p>Clozapine</p> Signup and view all the answers

    Which formulation is available for Igalmi?

    <p>All of the above</p> Signup and view all the answers

    Which antipsychotic has a high risk of akathisia and anxiety, but a less severe risk of weight gain compared to aripiprazole?

    <p>Cariprazine</p> Signup and view all the answers

    Which antipsychotic is classified as the most effective agent in the text?

    <p>Clozapine</p> Signup and view all the answers

    True or false: Dose titration is required when using clozapine?

    <p>True</p> Signup and view all the answers

    Which antipsychotic is known for its metabolic neutrality as a benefit?

    <p>Lurasidone</p> Signup and view all the answers

    Which antipsychotic is associated with post-injection delirium/sedation syndrome according to the black box warning?

    <p>Olanzapine</p> Signup and view all the answers

    Which generation of antipsychotics primarily act as dopamine and serotonin antagonists?

    <p>Second</p> Signup and view all the answers

    What is the first-line choice between atypical and typical antipsychotics?

    <p>Atypical</p> Signup and view all the answers

    Which antipsychotics pose the risk of hyperprolactinemia due to dopamine antagonism?

    <p>Both typical and atypical</p> Signup and view all the answers

    Which symptom is associated with neuroleptic malignant syndrome (NMS)?

    <p>Rigidity</p> Signup and view all the answers

    What is the recommended initial action in the treatment of neuroleptic malignant syndrome?

    <p>Discontinue the offending agent</p> Signup and view all the answers

    Which condition is a contraindication for deutetrabenazine?

    <p>Hepatic impairment</p> Signup and view all the answers

    What is a common long-term effect of hyperprolactinemia due to dopamine antagonism?

    <p>Infertility</p> Signup and view all the answers

    'Pseudo-parkinsonism' associated with antipsychotics presents with which symptom?

    <p>Shuffled gait</p> Signup and view all the answers

    Which type of antipsychotic has a higher risk of extrapyramidal symptoms?

    <p>Typical antipsychotics.</p> Signup and view all the answers

    What is the recommended first-line treatment for acute agitation and aggression?

    <p>Non-pharmacological interventions</p> Signup and view all the answers

    Which atypical antipsychotic has a unique warning related to bronchospasms with inhalation?

    <p>Loxapine</p> Signup and view all the answers

    How often is haloperidol decanoate given?

    <p>Every 4 weeks</p> Signup and view all the answers

    Which antipsychotic has a unique adverse effect of metallic taste and tongue numbness when taken sublingually?

    <p>Asenapine</p> Signup and view all the answers

    What is the primary mechanism of action for aripiprazole?

    <p>Partial dopamine and serotonin agonist</p> Signup and view all the answers

    Which antipsychotic is contraindicated in patients with asthma or COPD?

    <p>Loxapine</p> Signup and view all the answers

    What is the risk of metabolic abnormalities associated with aripiprazole?

    <p>Low risk</p> Signup and view all the answers

    In the mesolimbic system, an increase in dopamine causes negative symptoms.

    <p>False</p> Signup and view all the answers

    In the nigrostriatal pathway, there is an increase in dopamine and it is associated with drug side effects like EPS and TD.

    <p>False</p> Signup and view all the answers

    The tuberoinfundibular pathway in schizophrenia has an increase in dopamine.

    <p>False</p> Signup and view all the answers

    Schizophrenia onset typically begins around the age of 30.

    <p>False</p> Signup and view all the answers

    Corticosteroids are substances that exacerbate psychosis.

    <p>True</p> Signup and view all the answers

    Positive symptoms of schizophrenia include blunted affect and poor self-care.

    <p>False</p> Signup and view all the answers

    Risperidone long-acting injectable given every two weeks is Risperdal Consta.

    <p>False</p> Signup and view all the answers

    Ziprasidone requires at least a 1000 kcal meal to work effectively.

    <p>False</p> Signup and view all the answers

    Pimavanserin's main adverse effect is peripheral edema.

    <p>False</p> Signup and view all the answers

    Igalmi has formulations available in IV and oral tablet forms.

    <p>False</p> Signup and view all the answers

    Aripiprazole is recommended as the first-line treatment for treatment-resistant schizophrenia.

    <p>False</p> Signup and view all the answers

    Pimavanserin is FDA approved for Parkinson's disease psychosis due to its agonistic effect on 5-ht2a receptors.

    <p>False</p> Signup and view all the answers

    Atypical antipsychotics primarily act as dopamine and norepinephrine antagonists.

    <p>False</p> Signup and view all the answers

    Extrapyramidal symptoms can present as akathisia, dystonia, pseudo-parkinsonism, and tardive dyskinesia.

    <p>True</p> Signup and view all the answers

    Neuroleptic malignant syndrome (NMS) occurs only in the early stages of antipsychotic treatment.

    <p>False</p> Signup and view all the answers

    Violent muscle contractions and rigidity are key symptoms of akathisia.

    <p>False</p> Signup and view all the answers

    VMAT2 inhibitors are only used for treating neuroleptic malignant syndrome (NMS).

    <p>False</p> Signup and view all the answers

    Haloperidol lactate is commonly used for long-term management of psychosis.

    <p>False</p> Signup and view all the answers

    Hyperprolactinemia due to dopamine antagonism can lead to infertility as a short-term effect.

    <p>True</p> Signup and view all the answers

    Typical antipsychotics are more beneficial for reducing negative symptoms compared to atypical antipsychotics.

    <p>False</p> Signup and view all the answers

    Low-potency typical antipsychotics include fluphenazine and haloperidol.

    <p>False</p> Signup and view all the answers

    Haloperidol is available in oral tablet form only.

    <p>False</p> Signup and view all the answers

    Bromocriptine is commonly used as a treatment for extrapyramidal symptoms like akathisia.

    <p>False</p> Signup and view all the answers

    Haloperidol decanoate is given every 2 weeks.

    <p>False</p> Signup and view all the answers

    Fluphenazine has a long onset of action and requires oral overlap.

    <p>False</p> Signup and view all the answers

    Aripiprazole has a high risk of metabolic abnormalities.

    <p>False</p> Signup and view all the answers

    Asenapine patch should be applied on the lower back.

    <p>False</p> Signup and view all the answers

    Brexpiprazole has no dose adjustments needed in renal or hepatic impairment.

    <p>False</p> Signup and view all the answers

    Fluphenazine is contraindicated in patients with severe CNS depression.

    <p>True</p> Signup and view all the answers

    Lurasidone has a high risk of EPS.

    <p>False</p> Signup and view all the answers

    Olanzapine is not available in oral formulations for acute agitation and aggression.

    <p>False</p> Signup and view all the answers

    Quetiapine has a high risk of QTc prolongation.

    <p>True</p> Signup and view all the answers

    Risperidone is contraindicated in patients with asthma or COPD.

    <p>False</p> Signup and view all the answers

    Ziprasidone has a high risk of metabolic syndrome compared to FGAs.

    <p>False</p> Signup and view all the answers

    Cariprazine is recommended in severe renal and hepatic impairment.

    <p>False</p> Signup and view all the answers

    Iloperidone has a high risk of orthostatic hypotension, glucose, and lipid abnormalities.

    <p>True</p> Signup and view all the answers

    Lurasidone must be taken on an empty stomach to improve bioavailability.

    <p>False</p> Signup and view all the answers

    Olanzapine is primarily metabolized by CYP3A4.

    <p>False</p> Signup and view all the answers

    Zyprexa Relprevv does not require continuous monitoring after administration.

    <p>False</p> Signup and view all the answers

    Paliperidone is contraindicated in patients with hypersensitivity to olanzapine.

    <p>False</p> Signup and view all the answers

    Quetiapine is commonly used in the treatment of ICU delirium and sleep disorders.

    <p>True</p> Signup and view all the answers

    Risperidone is available in solution form only.

    <p>False</p> Signup and view all the answers

    Aripiprazole has a high risk of akathisia and anxiety compared to other antipsychotics.

    <p>False</p> Signup and view all the answers

    Lumateperon is contraindicated in moderate-severe hepatic impairment.

    <p>True</p> Signup and view all the answers

    The primary mechanism of action for olanzapine/samidorphan is as a dopamine antagonist.

    <p>False</p> Signup and view all the answers

    Quetiapine should be taken with a full meal for optimal absorption.

    <p>False</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser