Benefits of Long-Acting Injections and Acute Agitation Interventions

What is a key diagnostic requirement for schizophrenia according to DSM-5?

Which of the following substances is known to exacerbate psychosis?

What are some medical conditions that can present with psychosis?

What is the main concern with ziprasidone use?

Which antipsychotic causes a metallic taste as a side effect?

What is the recommended treatment for treatment-resistant schizophrenia?

Which formulation is available for Igalmi?

Which antipsychotic has a high risk of akathisia and anxiety, but a less severe risk of weight gain compared to aripiprazole?

Which antipsychotic is classified as the most effective agent in the text?

True or false: Dose titration is required when using clozapine?

Which antipsychotic is known for its metabolic neutrality as a benefit?

Which antipsychotic is associated with post-injection delirium/sedation syndrome according to the black box warning?

Which generation of antipsychotics primarily act as dopamine and serotonin antagonists?

What is the first-line choice between atypical and typical antipsychotics?

Which antipsychotics pose the risk of hyperprolactinemia due to dopamine antagonism?

Which symptom is associated with neuroleptic malignant syndrome (NMS)?

What is the recommended initial action in the treatment of neuroleptic malignant syndrome?

Which condition is a contraindication for deutetrabenazine?

What is a common long-term effect of hyperprolactinemia due to dopamine antagonism?

'Pseudo-parkinsonism' associated with antipsychotics presents with which symptom?

Which type of antipsychotic has a higher risk of extrapyramidal symptoms?

What is the recommended first-line treatment for acute agitation and aggression?

Which atypical antipsychotic has a unique warning related to bronchospasms with inhalation?

How often is haloperidol decanoate given?

Which antipsychotic has a unique adverse effect of metallic taste and tongue numbness when taken sublingually?

What is the primary mechanism of action for aripiprazole?

Which antipsychotic is contraindicated in patients with asthma or COPD?

What is the risk of metabolic abnormalities associated with aripiprazole?

In the mesolimbic system, an increase in dopamine causes negative symptoms.

In the nigrostriatal pathway, there is an increase in dopamine and it is associated with drug side effects like EPS and TD.

The tuberoinfundibular pathway in schizophrenia has an increase in dopamine.

Schizophrenia onset typically begins around the age of 30.

Corticosteroids are substances that exacerbate psychosis.

Positive symptoms of schizophrenia include blunted affect and poor self-care.

Risperidone long-acting injectable given every two weeks is Risperdal Consta.

Ziprasidone requires at least a 1000 kcal meal to work effectively.

Pimavanserin's main adverse effect is peripheral edema.

Igalmi has formulations available in IV and oral tablet forms.

Aripiprazole is recommended as the first-line treatment for treatment-resistant schizophrenia.

Pimavanserin is FDA approved for Parkinson's disease psychosis due to its agonistic effect on 5-ht2a receptors.

Atypical antipsychotics primarily act as dopamine and norepinephrine antagonists.

Extrapyramidal symptoms can present as akathisia, dystonia, pseudo-parkinsonism, and tardive dyskinesia.

Neuroleptic malignant syndrome (NMS) occurs only in the early stages of antipsychotic treatment.

Violent muscle contractions and rigidity are key symptoms of akathisia.

VMAT2 inhibitors are only used for treating neuroleptic malignant syndrome (NMS).

Haloperidol lactate is commonly used for long-term management of psychosis.

Hyperprolactinemia due to dopamine antagonism can lead to infertility as a short-term effect.

Typical antipsychotics are more beneficial for reducing negative symptoms compared to atypical antipsychotics.

Low-potency typical antipsychotics include fluphenazine and haloperidol.

Haloperidol is available in oral tablet form only.

Bromocriptine is commonly used as a treatment for extrapyramidal symptoms like akathisia.

Haloperidol decanoate is given every 2 weeks.

Fluphenazine has a long onset of action and requires oral overlap.

Aripiprazole has a high risk of metabolic abnormalities.

Asenapine patch should be applied on the lower back.

Brexpiprazole has no dose adjustments needed in renal or hepatic impairment.

Fluphenazine is contraindicated in patients with severe CNS depression.

Lurasidone has a high risk of EPS.

Olanzapine is not available in oral formulations for acute agitation and aggression.

Quetiapine has a high risk of QTc prolongation.

Risperidone is contraindicated in patients with asthma or COPD.

Ziprasidone has a high risk of metabolic syndrome compared to FGAs.

Cariprazine is recommended in severe renal and hepatic impairment.

Iloperidone has a high risk of orthostatic hypotension, glucose, and lipid abnormalities.

Lurasidone must be taken on an empty stomach to improve bioavailability.

Olanzapine is primarily metabolized by CYP3A4.

Zyprexa Relprevv does not require continuous monitoring after administration.

Paliperidone is contraindicated in patients with hypersensitivity to olanzapine.

Quetiapine is commonly used in the treatment of ICU delirium and sleep disorders.

Risperidone is available in solution form only.

Aripiprazole has a high risk of akathisia and anxiety compared to other antipsychotics.

Lumateperon is contraindicated in moderate-severe hepatic impairment.

The primary mechanism of action for olanzapine/samidorphan is as a dopamine antagonist.

Quetiapine should be taken with a full meal for optimal absorption.