BDS10015 Histopathology of Benign Oral Soft Tissue Lesions

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Which of the following is a common site for keratoacanthoma?

Outer edge of the vermillion border of lips

What is the etiology of keratoacanthoma?

Viral factors (HPV 26, 37)

How does keratoacanthoma clinically present?

Asymptomatic, more common in older males

What is the histopathological feature of keratoacanthoma?

Well-differentiated squamous cell carcinoma

Which of the following is NOT a possible etiology for keratoacanthoma?

Bacterial infection

What is the typical age group for the occurrence of keratoacanthoma?

Older adults, especially males

Which of the following is a possible cause for keratoacanthoma?

Actinic radiation

What distinguishes keratoacanthoma from squamous cell carcinoma histopathologically?

Presence of cystic spaces lined by endothelial cells

Which statement about keratoacanthoma is true?

$ ext{5-10} ext{%}$ of keratoacanthomas regress spontaneously without treatment.

What is a distinguishing feature of keratoacanthoma?

$ ext{It}$ has a central crater filled with keratin.

What differentiates keratoacanthoma from squamous cell carcinoma?

$ ext{Keratoacanthoma}$ does not metastasize, whereas squamous cell carcinoma does.

What distinguishes keratoacanthoma from basal cell carcinoma?

$ ext{Keratoacanthoma}$ resembles well-differentiated squamous cell carcinoma, while basal cell carcinoma does not.

Which of the following benign neoplasms is restricted to the craniofacial skeleton and is rare in other bones?

Osteoma

Which of the following benign neoplasms is characterized by variable abnormalities in bone, skin, and teeth as well as colorectal polyps?

Osteoma

Why is it wise to consider chondroma of the jaw as a potential chondrosarcoma?

Because the microscopic distinction between benign chondroma and low-grade chondrosarcoma of the jaw is difficult

Which condition presents as a tumor-like condition characterized by the presence of normal tissue in an exaggerating manner?

Hamartoma

Which benign neoplasm is a benign vascular hamartoma affecting the mucosa and is considered as a tumor of infancy that shows rapid growth, followed by gradual involution?

Haemangioma

What is the most common site of lymphangioma intraorally?

Anterior 2/3 of the tongue

Which benign neoplasm consists of small blood spaces lined by endothelial cells that are separated by connective tissue stroma?

Haemangioma

Which benign neoplasm arises on the surface of bone causing facial deformity?

Osteoma

Which benign hamartomatus tumorlike growth of lymphatic vessels has a marked predilection to the head & neck?

Lymphangioma

What is characteristic of Gardner’s syndrome?

High risk for transformation of colorectal polyps into adenocarcinoma if untreated

In which condition does a vascular malformation persist throughout life and is present at birth?

Sturge-Weber disease

What is characteristic of a cavernous haemangioma?

Consists of large blood spaces that may show papillary enfolding

Which lesion shows rapid enlargement to its full size of 1-2 cm over 6 weeks?

Keratoacanthoma

What is the characteristic feature of Antoni type A in Schwanoma histopathology?

Palisading arrangement of cells and their nuclei in rows

Which benign neoplasm is believed to be reactive hyperplasia of fibrous connective tissue rather than a true neoplasm?

Fibroma

Which benign neoplasm appears as a sessile mass affecting both males and females at middle age?

Granular cell tumor

What is the most common site for Granular cell tumor?

Tongue

Which benign neoplasm is a slowly growing, asymptomatic, soft swelling with a smooth surface?

Lipoma

What is the differential diagnosis for Granular cell tumor?

Congenital epulis of newborn

Which benign neoplasm is composed of interlacing bundles of spindle-shaped cells with wavy nuclei in delicate connective tissue?

Neurofibroma

What is the lab finding associated with Melanotic neuroectodermal tumor of infancy?

High levels of urinary vanillylmandelic acid

Learn about the histopathological features of benign soft tissue lesions of the oral mucosa including lymphangioma, haemangioma, lipoma, genodermatoses, and local reactive lesions. Understand how histopathology plays a role in the diagnostic process.

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