BDS10014 Oral Epithelial Dysplasia Lecture

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Which of the following is a characteristic feature of erythroplakia?

Granular appearance

Thick and adherent plaques

Surface projections

Soft and velvety texture (correct)

Which virus is less commonly associated with chronic infections that may lead to oral potentially malignant disorders?

Syphilis

Candida albicans

Epstein-Barr virus (correct)

HPV

What does leukoplakia denote?

A non-clinical term for white patches on oral mucosa

An infectious lesion on the oral mucosa

A clinical term for white plaque or patch on oral mucosa (correct)

A specific histopathologic tissue alteration

What is a common site for erythroplakia?

Tongue Signup and view all the answers

Which of the following is a characteristic feature of thick or fissured leukoplakia?

Deep fissures Signup and view all the answers

What is the primary effect of alcohol in relation to the oral mucosa?

Decrease in efficiency of detoxification of carcinogenic material Signup and view all the answers

What is an intrinsic factor contributing to oral potentially malignant disorders?

Nutritional deficiency Signup and view all the answers

What distinguishes proliferative verrucous leukoplakia from other clinical variants of leukoplakia?

Multifocal distribution and high recurrence Signup and view all the answers

Which of the following is a characteristic feature of speckled leukoplakia?

Immature atrophic epithelial cells Signup and view all the answers

What is the clinical appearance of mild or thin leukoplakia?

Soft flat translucent plaques Signup and view all the answers

What distinguishes actinic cheilitis from other clinical differential diagnoses?

Accelerated tissue damage due to chronic exposure to sunlight Signup and view all the answers

Which of the following is NOT a clinical feature of actinic cheilitis?

Diffuse gray or white palatal mucosa Signup and view all the answers

What is the histopathological feature commonly seen in actinic cheilitis?

Varying degrees of epithelial dysplasia Signup and view all the answers

Which condition is completely reversible upon discontinuation of the tobacco habit?

Nicotine stomatitis Signup and view all the answers

What is the characteristic oral mucosal presentation in oral submucous fibrosis?

Marble-like pallor with progressive stiffness Signup and view all the answers

Which feature is NOT associated with nicotine stomatitis?

Diffusely gray or white palatal mucosa Signup and view all the answers

Which condition is characterized by chronic progressive scarring of the oral mucosa?

Oral submucous fibrosis Signup and view all the answers

What is a common etiological factor for actinic cheilitis?

Chronic sun exposure Signup and view all the answers

Which feature is characteristic of solar (actinic) elastosis?

Amorphous acellular basophilic change in the connective tissue Signup and view all the answers

What is a common feature of nicotine stomatitis histopathology?

Intact basement membrane Signup and view all the answers

Which statement about oral potentially malignant disorders (OPMD) is correct?

OPMD may not show signs of epithelial dysplasia such as leukoplakia and erythroplakia but always presents with architectural changes Signup and view all the answers

Which text would provide relevant information for understanding the histopathological aspects of oral epithelial dysplasia?

Robinson M et al. Soames’ and Southam’s Oral Pathology. 5th edition. Oxford University Press, 2018 pp 77-84 Signup and view all the answers

Which feature is NOT characteristic of oral submucous fibrosis?

Intact basement membrane Signup and view all the answers

What is the aim of the lecture on oral epithelial dysplasia?

To detail the histopathological aspects of oral epithelial dysplasia Signup and view all the answers

Which term is currently preferred to describe clinical presentations carrying a risk of cancer development in the oral cavity?

Leukoplakia Signup and view all the answers

What percentage of epithelial dysplasias become malignant?

5-18% Signup and view all the answers

What are the lesions included in the category of oral potentially malignant disorders?

Erythroplakia, Leukoplakia, Smokless tobacoo keratosis Signup and view all the answers

How is dysplasia usually graded?

Mild, moderate, severe, and hyperplastic Signup and view all the answers

Which of the following is NOT included in the category of oral potentially malignant disorders?

Actinic keratosis Signup and view all the answers

What is the histological meaning of dysplasia?

Abnormal formation of epithelium or any tissue Signup and view all the answers

What is the preferred term to describe clinical presentations carrying a risk of cancer development in the oral cavity?