35 Questions
Which of the following is a characteristic feature of erythroplakia?
Soft and velvety texture
Which virus is less commonly associated with chronic infections that may lead to oral potentially malignant disorders?
Epstein-Barr virus
What does leukoplakia denote?
A clinical term for white plaque or patch on oral mucosa
What is a common site for erythroplakia?
Tongue
Which of the following is a characteristic feature of thick or fissured leukoplakia?
Deep fissures
What is the primary effect of alcohol in relation to the oral mucosa?
Decrease in efficiency of detoxification of carcinogenic material
What is an intrinsic factor contributing to oral potentially malignant disorders?
Nutritional deficiency
What distinguishes proliferative verrucous leukoplakia from other clinical variants of leukoplakia?
Multifocal distribution and high recurrence
Which of the following is a characteristic feature of speckled leukoplakia?
Immature atrophic epithelial cells
What is the clinical appearance of mild or thin leukoplakia?
Soft flat translucent plaques
What distinguishes actinic cheilitis from other clinical differential diagnoses?
Accelerated tissue damage due to chronic exposure to sunlight
Which of the following is NOT a clinical feature of actinic cheilitis?
Diffuse gray or white palatal mucosa
What is the histopathological feature commonly seen in actinic cheilitis?
Varying degrees of epithelial dysplasia
Which condition is completely reversible upon discontinuation of the tobacco habit?
Nicotine stomatitis
What is the characteristic oral mucosal presentation in oral submucous fibrosis?
Marble-like pallor with progressive stiffness
Which feature is NOT associated with nicotine stomatitis?
Diffusely gray or white palatal mucosa
Which condition is characterized by chronic progressive scarring of the oral mucosa?
Oral submucous fibrosis
What is a common etiological factor for actinic cheilitis?
Chronic sun exposure
Which feature is characteristic of solar (actinic) elastosis?
Amorphous acellular basophilic change in the connective tissue
What is a common feature of nicotine stomatitis histopathology?
Intact basement membrane
Which statement about oral potentially malignant disorders (OPMD) is correct?
OPMD may not show signs of epithelial dysplasia such as leukoplakia and erythroplakia but always presents with architectural changes
Which text would provide relevant information for understanding the histopathological aspects of oral epithelial dysplasia?
Robinson M et al. Soames’ and Southam’s Oral Pathology. 5th edition. Oxford University Press, 2018 pp 77-84
Which feature is NOT characteristic of oral submucous fibrosis?
Intact basement membrane
What is the aim of the lecture on oral epithelial dysplasia?
To detail the histopathological aspects of oral epithelial dysplasia
Which term is currently preferred to describe clinical presentations carrying a risk of cancer development in the oral cavity?
Leukoplakia
What percentage of epithelial dysplasias become malignant?
5-18%
What are the lesions included in the category of oral potentially malignant disorders?
Erythroplakia, Leukoplakia, Smokless tobacoo keratosis
How is dysplasia usually graded?
Mild, moderate, severe, and hyperplastic
Which of the following is NOT included in the category of oral potentially malignant disorders?
Actinic keratosis
What is the histological meaning of dysplasia?
Abnormal formation of epithelium or any tissue
What is the preferred term to describe clinical presentations carrying a risk of cancer development in the oral cavity?
Leukoplakia
What are examples of oral potentially malignant disorders?
Erythroplakia, Leukoplakia, Smokless tobacoo keratosis
What do cytological abnormalities in dysplasia indicate?
The lesion is premalignant or malignant
What is the percentage range of epithelial dysplasias that become malignant?
5-18%
What is the primary focus of the lecture on oral epithelial dysplasia?
Histopathological aspects of oral epithelial dysplasia
Learn about the histopathological aspects of oral epithelial dysplasia, including the clinical features of different degrees and carcinoma-in-situ. Understand oral potentially malignant disorders and their association with cancer development in the oral cavity.
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