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Basics of Clinical Research

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Questions and Answers

What is the primary purpose of a cohort study?

To evaluate the effects of an intervention

To define the incidence and investigate potential causes of a condition (correct)

To compare the prevalence of risk factors between cases and controls

To describe the distribution patterns of variables

What is the main difference between a prospective and retrospective cohort study?

The type of variables measured

The number of subjects in the study

The timing of data collection and follow-up (correct)

The type of research question being answered

What is the purpose of a case-control study?

To compare the prevalence of risk factors between cases and controls (correct)

To define the incidence of a condition

To evaluate the effects of an intervention

To describe the distribution patterns of variables

What is the primary purpose of Good Clinical Practices (GCP's)?

To establish standards for the design, conduct, and reporting of research Signup and view all the answers

What type of study design involves an intervention?

Experimental design Signup and view all the answers

What is the main strength of a cross-sectional study?

Ability to describe the distribution patterns of variables Signup and view all the answers

What is the main purpose of Phase I studies in experimental research?

To test the safety of a treatment in a small number of healthy volunteers Signup and view all the answers

What is the primary focus of Phase IV studies in experimental research?

To assess the performance of a treatment after it has been approved by the FDA Signup and view all the answers

What is the primary purpose of a literature review in research?

To identify gaps in current knowledge and formulate a research question Signup and view all the answers

What is the main purpose of a study question or hypothesis in research?

To formulate a well-built clinical research question or hypothesis Signup and view all the answers

What are the five components of a well-built clinical research question or hypothesis?

Population, Intervention, Comparison, Outcome, and Setting Signup and view all the answers

What is the main purpose of the IRB in research?

To approve the study and ensure it meets ethical standards Signup and view all the answers