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Basic Structure of Immunoglobulins

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Questions and Answers

What is the function of immunoglobulins as antibodies?

Producing an immune response in the body
Acting as enzymes in cellular fluids
Combining with antigenic determinants to eliminate them (correct)
Serving as antigen receptors on the surface of a B-cell

What is the role of immunoglobulins as plasma membrane-bound receptors on B-cells?

Releasing antigens into the body
Intercepting and eliminating antigenic determinants
Signal reception for B-cell activation (correct)
Acting as free antibodies in cellular fluids

What is the definition of an antigen?

A glycoprotein produced by plasma cells
A substance that functions as an antibody
A substance that induces a specific immune response (correct)
A portion of an immunoglobulin structure

What does the term 'antigenic determinant' refer to?

A portion of an antigen that combines with specific immune response products (A) Signup and view all the answers

How are immunoglobulins named based on their migration in an electric field?

They are named because they migrate with globular proteins in an electrical field (C) Signup and view all the answers

What is the result of cleavage of Ig with papain?

Two Fab fragments and one Fc fragment (C) Signup and view all the answers

What is the term for the process by which antibodies cross epithelial layers?

Transcytosis (A) Signup and view all the answers

What is the term for the killing of cells mediated by antibodies and immune cells?

Antibody-dependent cell-mediated cytotoxicity (ADCC) (C) Signup and view all the answers

What is the source of pure immunoglobulin that made sequencing possible?

Multiple myeloma patients (C) Signup and view all the answers

What are the two types of light chains in immunoglobulins?

Kappa (κ) and lambda (λ) (D) Signup and view all the answers

What is the term for the process by which antibodies help to eliminate pathogens by marking them for destruction?

Opsonization (D) Signup and view all the answers

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