Basic Structure of Immunoglobulins
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Questions and Answers

What is the function of immunoglobulins as antibodies?

  • Producing an immune response in the body
  • Acting as enzymes in cellular fluids
  • Combining with antigenic determinants to eliminate them (correct)
  • Serving as antigen receptors on the surface of a B-cell

What is the role of immunoglobulins as plasma membrane-bound receptors on B-cells?

  • Releasing antigens into the body
  • Intercepting and eliminating antigenic determinants
  • Signal reception for B-cell activation (correct)
  • Acting as free antibodies in cellular fluids

What is the definition of an antigen?

  • A glycoprotein produced by plasma cells
  • A substance that functions as an antibody
  • A substance that induces a specific immune response (correct)
  • A portion of an immunoglobulin structure

What does the term 'antigenic determinant' refer to?

<p>A portion of an antigen that combines with specific immune response products (A)</p> Signup and view all the answers

How are immunoglobulins named based on their migration in an electric field?

<p>They are named because they migrate with globular proteins in an electrical field (C)</p> Signup and view all the answers

What is the result of cleavage of Ig with papain?

<p>Two Fab fragments and one Fc fragment (C)</p> Signup and view all the answers

What is the term for the process by which antibodies cross epithelial layers?

<p>Transcytosis (A)</p> Signup and view all the answers

What is the term for the killing of cells mediated by antibodies and immune cells?

<p>Antibody-dependent cell-mediated cytotoxicity (ADCC) (C)</p> Signup and view all the answers

What is the source of pure immunoglobulin that made sequencing possible?

<p>Multiple myeloma patients (C)</p> Signup and view all the answers

What are the two types of light chains in immunoglobulins?

<p>Kappa (κ) and lambda (λ) (D)</p> Signup and view all the answers

What is the term for the process by which antibodies help to eliminate pathogens by marking them for destruction?

<p>Opsonization (D)</p> Signup and view all the answers

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