Basal Nuclei and Motor Control
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Questions and Answers

What is the primary function of the basal nuclei in motor control?

  • Inhibiting muscle tone throughout the body (correct)
  • Exciting muscle tone throughout the body
  • Maintaining posture
  • Initiating voluntary motor behavior
  • What is the primary neurotransmitter released by neurons in the basal nuclei that is affected in Parkinson's disease?

  • GABA
  • Acetylcholine
  • Dopamine (correct)
  • Serotonin
  • What is the structure that forms the walls of the third ventricular cavity and consists of the thalamus and hypothalamus?

  • Basal nuclei
  • Diencephalon (correct)
  • Cerebellum
  • Brainstem
  • What is the name of the complex feedback loop that links the motor cortical regions, basal nuclei, and thalamus?

    <p>Not specified in the text</p> Signup and view all the answers

    Why can't dopamine be given as a treatment for Parkinson's disease?

    <p>It is unable to cross the blood-brain barrier</p> Signup and view all the answers

    What is the primary function of the thalamus in sensory processing?

    <p>To screen out insignificant signals and route important sensory impulses to appropriate areas of the cortex</p> Signup and view all the answers

    What is the primary role of the hypothalamus in the autonomic nervous system?

    <p>To serve as a major coordinating center for the autonomic nervous system</p> Signup and view all the answers

    Which of the following structures is NOT part of the limbic system?

    <p>Cerebellum</p> Signup and view all the answers

    What is the primary function of the hypothalamus in regulating body temperature?

    <p>To regulate both heat production and heat loss</p> Signup and view all the answers

    What is the role of the thalamus in motor control?

    <p>To positively reinforce voluntary motor behavior</p> Signup and view all the answers

    Study Notes

    Basal Nuclei (Basal Ganglia)

    • Located deep within cerebral white matter, consisting of several masses of grey matter
    • Play an important inhibitory role in motor control
    • Inhibiting muscle tone throughout the body
    • Maintain proper muscle tone by balancing excitatory and inhibitory inputs to neurons
    • Select and maintain purposeful motor activity
    • Suppress useless or unwanted patterns of movement
    • Help monitor and coordinate slow, sustained contractions (especially related to posture)

    Function of Basal Nuclei

    • Do not directly influence efferent motor neurons
    • Modify ongoing activity in motor pathways
    • Receive and send out a large volume of information through fibers linking them to brain regions
    • Involved in a complex feedback loop with motor cortical regions, thalamus, and brain regions

    Parkinson's Disease (PD)

    • Gradual destruction of neurons that release neurotransmitter dopamine in the basal nuclei
    • Characteristic motor disturbances:
      • Rigidity: increased muscle tone
      • Resting tremor: involuntary, useless or unwanted movements
      • Slowness in initiating and carrying out different motor behaviors
    • Standard treatment: administration of levodopa (L-dopa), a precursor of dopamine that can enter the brain from the blood

    The Thalamus

    • Located deep within the brain, near the basal nuclei, forming the walls of the third ventricular cavity
    • Serves as a "relay station" for preliminary processing of sensory input
    • Screens out insignificant signals and routes important sensory impulses to appropriate areas of the somatosensory cortex and other brain regions
    • Helps direct attention to stimuli of interest
    • Positively reinforces voluntary motor behavior initiated by the cortex

    The Hypothalamus

    • Collection of specific nuclei and associated fibers, lying beneath the thalamus
    • Important link between the autonomic nervous system and the endocrine system
    • Integrating center for many important homeostatic functions
    • Regulates the internal environment
    • Functions:
      • Controls body temperature (thermostat)
      • Controls thirst and urine output
      • Controls food intake
      • Controls anterior pituitary hormone secretion
      • Produces posterior pituitary hormones
      • Controls uterine contractions and milk ejection
      • Serves as a major ANS coordinating center, affecting all smooth muscles, cardiac muscles, and exocrine glands
      • Plays a role in emotional and behavioral patterns
      • Participates in the sleep-wake cycle

    The Limbic System

    • Functional system consisting of a ring of forebrain structures surrounding the brain stem and interconnected by intricate neuron pathways
    • Includes portions of the lobes of cerebral cortex, basal nuclei, hippocampus, thalamus, hypothalamus, and amygdala
    • Associated with:
      • Emotions
      • Behavior
      • Motivation
      • Memory
      • Olfaction

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    Description

    Learn about the basal nuclei, also known as basal ganglia, and their role in motor control, including maintaining muscle tone and suppressing unwanted movements.

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