30 Questions
What are the common symptoms of salmonellosis?
All of the above
How long is the typical incubation period for salmonellosis?
1-3 days
What is the typical duration of salmonellosis?
48-72 hours
How are antibiotics used in the treatment of salmonellosis?
Antibiotics are not needed and may prolong the convalescent carrier state
What is the characteristic rash seen in typhoid fever?
Rose spots
What are the common specimen types used to diagnose typhoid fever?
Blood, bone marrow, urine, and stool
Which of the following best describes the symptoms of Neisseria gonorrhoeae infection in men?
Yellow, purulent urethral discharge and painful urination
What is a common characteristic of Neisseria gonorrhoeae infection in women?
They are more often asymptomatic than men
Which of the following is the diagnostic method for Neisseria gonorrhoeae infection in men?
A smear of urethral exudate showing gram-negative diplococci
Which of the following best describes the presentation of Neisseria gonorrhoeae infection in women?
Greenish-yellow cervical discharge and intermenstrual bleeding
What is the diagnostic method for Neisseria gonorrhoeae infection at sites other than the urethra?
A positive culture is needed
Which of the following is a rare complication of Neisseria gonorrhoeae infection?
Disseminated infection via invasion of the bloodstream
Which of the following statements about Neisseria species is correct?
They are non-motile, piliated, Gram-negative diplococci.
What is the key difference between Neisseria gonorrhoeae and Neisseria meningitidis?
N. gonorrhoeae is encapsulated, while N. meningitidis is unencapsulated.
Which of the following statements about the lipooligosaccharide (LOS) of Neisseria species is correct?
LOS is shorter and more highly branched than typical LPS, with non-repeating O-antigen side chains.
Which of the following proteins are involved in the pathogenesis of Neisseria species?
PorA and PorB porins, and Opacity (Opa) proteins.
Which of the following statements about Acinetobacter baumannii is correct?
It causes nosocomial infections.
What is the significance of the IgA protease expressed by Neisseria species?
It cleaves IgA1, an important component of mucosal immunity.
Which of the following is a potential complication of Neisseria gonorrhoeae infection?
Salpingitis
What percentage of women with salpingitis due to Neisseria gonorrhoeae infection experience infertility?
20%
Which of the following is a risk factor for Neisseria meningitidis infection?
Recent viral or mycoplasma upper respiratory tract infection
How does the outer membrane of Neisseria gonorrhoeae differ from that of Escherichia coli?
Neisseria gonorrhoeae has a shorter, highly branched O-antigen portion of LOS, while E. coli has a heat-stable O-antigen.
Why is it challenging to develop a vaccine for Neisseria gonorrhoeae?
It exhibits antigenic phase variation in surface structures like pili, LOS, and Opa proteins.
Which of the following is a prevention method for Neisseria gonorrhoeae infection?
Barrier methods
Which phase of whooping cough is characterized by paroxysms of cough followed by a "whoop"?
Paroxysmal phase
What is the primary diagnostic specimen for whooping cough?
Nasal swab or nasal saline wash
Which of the following media is used for culturing the causative agent of whooping cough?
Bordet-Gengou or Regan-Lowe media
What is the drug of choice for the treatment of whooping cough?
Erythromycin
Which of the following is a potential complication of whooping cough?
Encephalopathy
What type of vaccine is used for the prevention of whooping cough?
Purified Bordetella proteins in combination with D & T toxoids
Prepare for your midterm exam by reviewing the bacteriologic characteristics of Neisseria gonorrhea and Neisseria meningitidis, including their morphology, biochemistry, and pathogenicity factors.
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