16 Questions
Which type of hemolysis is associated with Group B Streptococcus?
Alpha-hemolysis
What is the estimated number of invasive cases of Group A Streptococcus pyogenes infections with a mortality rate of 25%?
Over 650,000 cases
Which virulence factor allows Group A Streptococcus to destroy red blood cells and harvest iron from them?
Streptolysin O
What differentiates S.pyogenes from S.aureus in terms of hemolysin production?
Production of Streptolysin O
What is the function of exfoliative toxin produced by S. aureus?
Causes the upper layers of skin to slough off
Which enzyme allows S. aureus to penetrate deeper into the body by breaking down connective tissue integrity?
Hyaluronidase
What is the role of coagulase or staphylokinase produced by S. aureus?
Clots blood and may hide bacteria from phagocytes
Which virulence factor allows S. aureus to resist β-lactam antibiotics?
Protein A
What is the most common way for bacteria to enter the skin and cause cellulitis?
Via open wounds such as blisters and bites
Which bacteria are responsible for approximately 2/3rds of cellulitis cases?
Streptococcus pneumoniae
What is the analogy used to describe the effect of cellulitis on the skin?
A bacterial burn
What is a common risk factor for recurrent cellulitis according to the text?
Presence of skin abnormalities such as trauma or fungal infection
What is the function of streptokinases in Streptococcus pyogenes?
Dissolving blood clots
Which virulence factor of Streptococcus pyogenes allows for the spread of the bacteria through tissues?
Hyaluronidase
How do exotoxin A and C produced by S. pyogenes exert their pyrogenic properties?
Acting directly on the hypothalamus
What is the function of C5a peptidase in Streptococcus pyogenes?
Destroying C5a compliment protein
Test your knowledge of bacterial virulence factors by identifying their functions and effects. Learn about pili, capsule, exotoxins, and other key factors that contribute to bacterial pathogenicity.
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