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Questions and Answers
How is the flagellum of E. coli typically sized?
How is the flagellum of E. coli typically sized?
How many substructures is the bacterial flagellum divided into?
How many substructures is the bacterial flagellum divided into?
Where are polar flagella located on a bacterial cell?
Where are polar flagella located on a bacterial cell?
In what process does flagellum assembly start with?
In what process does flagellum assembly start with?
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Which protein is the major subunit of the flagellum?
Which protein is the major subunit of the flagellum?
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Apart from motility, what other function do flagella serve?
Apart from motility, what other function do flagella serve?
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Match the following cellular structures with their functions:
Match the following cellular structures with their functions:
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Match the following cellular structures with their characteristics:
Match the following cellular structures with their characteristics:
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Match the following cellular structures with their composition:
Match the following cellular structures with their composition:
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Match the following cellular structures with their types of cells:
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Match the following cellular structures with their functions in protein synthesis:
Match the following cellular structures with their functions in protein synthesis:
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Match the following cellular structures with their characteristics in prokaryotic cells:
Match the following cellular structures with their characteristics in prokaryotic cells:
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Match the following structures with their functions in prokaryotic cells:
Match the following structures with their functions in prokaryotic cells:
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Match the following components with their characteristics in prokaryotic cells:
Match the following components with their characteristics in prokaryotic cells:
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Match the following terms with their descriptions in prokaryotic cells:
Match the following terms with their descriptions in prokaryotic cells:
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Match the following structures with their functions in prokaryotic cells:
Match the following structures with their functions in prokaryotic cells:
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Match the following components with their functions in prokaryotic cells:
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Match the following structures with their characteristics in prokaryotic cells:
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Study Notes
Flagella are hairlike structures that act as an organelle of locomotion in prokaryotic and eukaryotic cells. Bacteria have flagella for movement and chemotaxis. The flagellum is composed of about 60 structural and regulatory proteins, including flagellin or FliC, which is the major subunit of the flagellum. The flagellum of Escherichia coli is typically about 10 µm long with a diameter of 20 nm.
Bacterial flagella come in two main types: polar and peritrichous. Polar flagella are located at one spot on the cell, while peritrichous flagella cover the entire cell surface. The flagellum is a supramolecular structure divided into three substructures: the filament, the hook, and the basal body. The filament is composed of about 20,000 flagellin (FliC) proteins, which are incorporated below the distal pentameric FliD cap.
The bacterial flagellum is assembled through a complex process involving several proteins. Flagellum assembly starts with the CM-associated components of the basal body and the secretion apparatus, followed by the remaining basal body components, the hook and hook-filament junction proteins, and finally the filament capping proteins.
Flagella not only serve as motility organelles but also have other functions. They can participate in biofilm formation, protein export, and adhesion. Flagellin, the major subunit of the flagellum, has been shown to function as an adhesin, playing a role in bacterial adhesion to and invasion into host cells. In various pathogens, such as Escherichia coli, Pseudomonas aeruginosa, and Clostridium difficile, flagellin and the distally located flagellar cap protein have been reported to function as adhesins.
In summary, bacterial flagella are complex structures composed of multiple proteins that serve as motility organelles and have additional functions such as adhesion and biofilm formation. The assembly process involves several proteins and the flagellum can have different types and numbers depending on the bacterial species.
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Description
Explore the composition, assembly process, and additional functions of bacterial flagella. Learn about the different types of bacterial flagella, the major subunit flagellin, and the complex structure involving the filament, hook, and basal body.