Bacterial Cell Structure and Envelope

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Questions and Answers

Which component forms the primary structure of the bacterial cell wall?

  • Cellulose
  • Lipid bilayer
  • Protein sheath
  • Peptidoglycan (correct)

What type of structures are flagella in bacteria classified as?

  • Inclusion bodies
  • Appendages (correct)
  • Cell wall extensions
  • Ribosomal structures

Which of the following describes the glycan strands in peptidoglycan?

  • Cross-linked peptides (correct)
  • Complex carbohydrates
  • Nucleic acid sequences
  • Fatty acid chains

What is the primary function of the bacterial cell envelope?

<p>Protecting the cell and maintaining its shape (D)</p> Signup and view all the answers

Which of the following best describes inclusion bodies in bacteria?

<p>Storage granules for nutrients or waste (C)</p> Signup and view all the answers

What is a primary characteristic of the cell wall of Gram-positive bacteria?

<p>It contains teichoic acid. (C), It lacks an outer membrane. (D)</p> Signup and view all the answers

Which component is found in the outer membrane of Gram-negative bacteria?

<p>Lipopolysaccharide (LPS) (B)</p> Signup and view all the answers

What is the role of porins in the outer membrane of Gram-negative bacteria?

<p>To facilitate the passage of small molecules (D)</p> Signup and view all the answers

Which of the following is a consequence of cell death in Gram-negative bacteria?

<p>Release of endotoxin causing fever (C)</p> Signup and view all the answers

What structural feature differentiates the cell wall of Gram-negative from Gram-positive bacteria?

<p>Presence of an outer membrane (D)</p> Signup and view all the answers

What is the function of the strong negative charge of the outer membrane in Gram-negative bacteria?

<p>To evade phagocytosis (B)</p> Signup and view all the answers

What does the term 'endotoxic shock' refer to?

<p>Reactions due to the presence of LPS from bacteria (B)</p> Signup and view all the answers

What component anchors the inner half of the outer membrane to the peptidoglycan layer in Gram-negative bacteria?

<p>Lipoproteins (B)</p> Signup and view all the answers

What is a significant structural feature of Gram-negative bacteria compared to Gram-positive bacteria?

<p>They contain an outer membrane. (D)</p> Signup and view all the answers

Which component is found in the cell wall of Gram-negative bacteria but not in Gram-positive bacteria?

<p>Porins (B)</p> Signup and view all the answers

How does the cell wall structure of Gram-negative bacteria contribute to their antibiotic resistance?

<p>The outer membrane acts as a barrier to certain antibiotics. (D)</p> Signup and view all the answers

Which of the following components is NOT present in the cell envelope of Gram-negative bacteria?

<p>Teichoic acid (D)</p> Signup and view all the answers

What role do lipopolysaccharides (LPS) play in the cell wall of Gram-negative bacteria?

<p>They contribute to the selective permeability of the outer membrane. (D)</p> Signup and view all the answers

What is the primary function of fimbriae in prokaryotic cells?

<p>Adhering to surfaces and promoting colonization (D)</p> Signup and view all the answers

What distinguishes pili from fimbriae in terms of structure and number?

<p>Pili are longer and fewer in number (D)</p> Signup and view all the answers

Which type of motility is associated with the function of pili in prokaryotic cells?

<p>Twitching motility (B)</p> Signup and view all the answers

Which protein is primarily responsible for the structure of pili?

<p>Pilin (B)</p> Signup and view all the answers

What roles do fimbriae play in biofilm formation?

<p>Enhancing adherence to nonliving surfaces (A)</p> Signup and view all the answers

In prokaryotic cells, how are sex pili particularly important?

<p>They allow direct DNA transfer during conjugation (C)</p> Signup and view all the answers

Which statement about fimbriae is NOT true?

<p>Fimbriae are always found at the poles of the cell (A)</p> Signup and view all the answers

How do fimbriae contribute to the colonization of host cells?

<p>By promoting attachment to host surfaces (C)</p> Signup and view all the answers

What role do the peptide cross-bridges play in the structure of peptidoglycan?

<p>They connect the glycan chains to form a solid matrix. (B)</p> Signup and view all the answers

Which of the following is true about the tetrapeptide side chains in peptidoglycan?

<p>They are attached to N-acetylmuramic acid. (A)</p> Signup and view all the answers

What is a primary function of the bacterial cell wall?

<p>It helps determine the shape of the bacterial cell. (C)</p> Signup and view all the answers

What can occur in bacteria that lack a cell wall when placed in a hypotonic environment?

<p>They may undergo osmotic lysis. (B)</p> Signup and view all the answers

Which amino sugars are the primary components of the carbohydrate backbone in peptidoglycan?

<p>N-acetylglucosamine and N-acetylmuramic acid. (A)</p> Signup and view all the answers

How does the chemical composition of the cell wall assist in clinical settings?

<p>It is used to differentiate between major types of bacteria. (C)</p> Signup and view all the answers

What protects bacteria from bursting due to osmotic pressure?

<p>Presence of a rigid peptidoglycan cell wall. (A)</p> Signup and view all the answers

What type of environment do bacteria typically thrive in regarding osmotic pressure?

<p>Hypotonic environments. (D)</p> Signup and view all the answers

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Study Notes

Bacterial Cell Structure

  • Peptidoglycan: A complex, semi-rigid layer outside the plasma membrane, essential for bacterial cell shape and integrity.
    • Composed of glycan strands cross-linked by peptides.
    • Glycan strands: Alternating N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) linked by glycosidic bonds.
    • Tetrapeptide side chains: Four amino acids attached to NAM in the glycan backbone.
    • Peptide cross-bridges: Short chains of amino acids linking tetrapeptide side chains.

Bacterial Cell Envelope

  • Gram-positive bacteria: Possess a thick peptidoglycan layer.
    • Teichoic acids: Embedded in peptidoglycan layer, contributing to the cell's negative charge.
    • More susceptible to antibiotics that target peptidoglycan synthesis.
  • Gram-negative bacteria: Have a thinner peptidoglycan layer and an additional outer membrane.
    • Outer membrane: Contains lipopolysaccharide (LPS) and porins.
      • LPS: An endotoxin released upon cell death, causing fever and shock.
      • Porins: Proteins forming channels for small molecules to cross the outer membrane.
    • Periplasmic space: Located between the inner and outer membranes.
    • Less susceptible to certain antibiotics due to the outer membrane barrier.

External Structures

  • Flagella: Long filamentous structures responsible for motility.
  • Axial filaments: Found in spirochetes, providing corkscrew-like motility.
  • Fimbriae: Short, hair-like appendages involved in adhesion to surfaces and host cells.
  • Pili: Longer than fimbriae, involved in conjugation (DNA transfer) and twitching motility.

Comparison of Gram-positive and Gram-negative Bacteria

Character Gram-positive Gram-negative
Overall thickness Thick peptidoglycan layer Thin peptidoglycan layer
Peptidoglycan Present Present
Teichoic acid Present Absent
Lipopolysaccharide Absent Present
Outer membrane Absent Present
Permeability to molecules Less selective More selective

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