Term 1 Biomedical Sciences

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Questions and Answers

Bacteria are prokaryotes. What does this mean?

  • They can move
  • They are small
  • Don't have a nucleus (correct)
  • Have a nucleus

Bacteria can move. What is the name of the structure that moves them?

  • Appendage
  • Tail
  • Whip
  • Flagellum (correct)

Examples of oral conditions caused by bacteria are

  • Periodontal disease (correct)
  • Caries (correct)
  • Coldsores
  • Thrush

The cell wall of gram negative bacteria produce endotoxins during cell lysis

<p>True (A)</p> Signup and view all the answers

The cell wall of gram negative bacteria produce endotoxins whilst the bacteria is replicating

<p>False (B)</p> Signup and view all the answers

What would you NOT expect to find in cell structure?

<p>Microflora (C)</p> Signup and view all the answers

Which of the following statements about the Golgi apparatus is INCORRECT?

<p>Plays an important part in cell division (D)</p> Signup and view all the answers

Which of the following statements about the nuclear envelope is INCORRECT?

<p>The outer layer is covered with cilia (C)</p> Signup and view all the answers

Which of the following statements about the nucleus is INCORRECT?

<p>Is the smallest feature in a cell (B)</p> Signup and view all the answers

Which of the following statements is false?

<p>The plasma membrane comprises a single layer (A)</p> Signup and view all the answers

Which of the following statements is INCORRECT?

<p>Each daughter nuclei contains 34 chromosomes (A)</p> Signup and view all the answers

Which organelle contains enzymes to digest foreign material?

<p>Lysosome (D)</p> Signup and view all the answers

Which organelle is known as the power house of the cell?

<p>Mitochondrion (A)</p> Signup and view all the answers

Fungal microflora is present throughout the human body

<p>True (A)</p> Signup and view all the answers

The diversity of fungal presence varies from person to person but will remain the same for all sites on an individual

<p>False (B)</p> Signup and view all the answers

The structural forms of fungi are

<p>Yeast (C), Mould (D)</p> Signup and view all the answers

The term commensal microflora refers to the pathogenic nature of micro-organisms to the host

<p>False (B)</p> Signup and view all the answers

The term dimorphic relates to the ability of fungi to

<p>Switch between being a yeast and a mould (C)</p> Signup and view all the answers

Which of the following statements on fungi are true?

<p>Fungi are eukaryotic organisms (B), Fungi are oral commensals of approximately 50% of humans (C), Fungal mycelium contains an abundance of hyphal elements (D)</p> Signup and view all the answers

Yeast is unlike bacteria in being

<p>Eukaryotic (A), Unicellular (C)</p> Signup and view all the answers

An example of a virus exhibiting viral latency is

<p>Herpes zoster (B)</p> Signup and view all the answers

Genetic material of a virus can be

<p>RNA (A), DNA (B)</p> Signup and view all the answers

Penetration occurs by the following

<p>Translocation (B), Fusion (C), Endocytosis (D)</p> Signup and view all the answers

Select the correct order of replication of viruses

<p>Adsorption, Penetration, Uncoating, Transcription, Synthesis of viral components, Assembly, Release (A)</p> Signup and view all the answers

Viruses are predominantly made out of

<p>Proteins (B)</p> Signup and view all the answers

Viruses can multiply by asexual and sexual reproduction

<p>False (B)</p> Signup and view all the answers

Why are viruses not classed as living organisms

<p>All of the above (D)</p> Signup and view all the answers

In order to survive, pathogens require a source of nutrients, protection from harmful elements and:

<p>Colonization of a niche in the host (B)</p> Signup and view all the answers

Some enveloped viruses use antigenic variation which makes it difficult for the immune system to recognise different strains of the virus. Which type of antigenic variation results in a major change in spike proteins due to gene reassortment?

<p>Antigenic shift (B)</p> Signup and view all the answers

Which pathogen type is always a member of the normal microbiota and only causes disease in an immunocompromised host?

<p>Opportunistic pathogen (B)</p> Signup and view all the answers

Which type of pathogen is an environmental microbe that is able to cause disease in an otherwise healthy individual?

<p>Primary pathogen (C)</p> Signup and view all the answers

Virulence factors can be described as:

<p>All of the above (D)</p> Signup and view all the answers

What kind of virulence factors are proteases, nucleases, phospholipases and glycohydrolases?

<p>Exoenzymes (A)</p> Signup and view all the answers

Which of these virulence factors act as adhesins?

<p>All of the above (D)</p> Signup and view all the answers

Which of these virulence factors assist in promoting colonization of the host?

<p>Adhesins (C)</p> Signup and view all the answers

Which of these virulence factors enable damage to be caused to the host?

<p>Toxins and exoenzymes (D)</p> Signup and view all the answers

Which virulence factor does Porphyromonas Gingivalis use which leads to disregulated immunity in the gingival tissues and breakdown of the structures around the teeth?

<p>Fimbraie and exoenzyme Gingipains (D)</p> Signup and view all the answers

The most abundant organisms on the human body are

<p>Microbes (A)</p> Signup and view all the answers

What type of medicine kills bacteria?

<p>Antibiotics (B)</p> Signup and view all the answers

Flashcards

Prokaryote (in bacteria)

Lacking a nucleus; genetic material is not enclosed within a membrane-bound nucleus.

Bacterial Flagellum

A whip-like appendage used for movement by bacteria.

Bacterial Oral Conditions

Diseases or conditions affecting the mouth, gums, and teeth, often caused by bacterial infections.

Gram-negative bacteria & endotoxins release

Release of endotoxins occurs when the cell is disrupted or lysed, releasing the toxin into the surrounding environment.

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Golgi apparatus

An organelle that packages and processes proteins.

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Nuclear envelope

Double membrane surrounding the nucleus in eukaryotic cells.

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Nucleus

The control center of the cell, containing genetic material (DNA).

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Plasma membrane

A double layer of lipids and proteins that surrounds a cell, controlling the entry and exit of substances.

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Lysosome Function

Organelle containing enzymes for breaking down foreign material and cellular debris.

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Mitochondrion

Organelle responsible for generating energy (ATP) through cellular respiration.

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Yeast

Single-celled fungi with a round or oval shape.

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Dimorphic Fungi

The ability of some fungi to exist in both yeast-like and mold-like forms.

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Commensal Microflora

Microorganisms that normally live harmlessly in or on the host and benefit from the association.

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Eukaryotic organism

Organisms whose cells have a nucleus enclosed within membranes.

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Viral Latency

Viral latency is the ability of a virus to remain dormant within a host cell

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Virus Replication Order

Adsorption, Penetration, Uncoating, Transcription, Synthesis of viral components, Assembly, Release

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Colonization of a pathogen

Colonization refers to the ability of pathogens to establish within a host

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Antigenic Variation

Antigenic shift causes a major change due to gene reassortment

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Opportunistic Pathogens

Opportunistic pathogens are members of the normal microbiota

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Primary pathogen

Primary pathogens are environmental microbes that cause disease in healthy individuals

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Virulence factors

Virulence factors enhance a microbes ability to cause disease

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Exoenzymes

Exoenzymes are examples of virulence factors

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Adhesins

Adhesins promote colonisation of the host

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Toxins and exoenzymes

Toxins and exoenzymes enable damage to be caused to the host

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Antibiotics

Antibiotics are a type of medicine that kills bacteria

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