Bacteria Associated with Periodontal Disease
18 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What are virulence factors in the context of periodontal disease?

  • Mechanisms that allow bacteria to colonize and damage tissues (correct)
  • Proteins released by host cells in response to infections
  • Methods that enhance the immune response against bacteria
  • Genetic markers related to periodontal disease susceptibility

    • Which of the following statements best describes lipopolysaccharides (LPS)?

  • They are endotoxins found in the outer layer of Gram-positive bacteria.
  • They are enzymes produced by bacteria that degrade host proteins.
  • They play a crucial role in the ability of bacteria to invade host tissues. (correct)
  • They are proteins that help bacteria evade the immune system.

    • Which environmental factor is known to impact the immune response in periodontal disease?

  • Consumption of a high-sugar diet
  • Tobacco smoking (correct)
  • Exposure to high levels of stress
  • Genetic predisposition to infections

    • What role do B-lymphocytes play in the immune response during periodontal disease?

    <p>Binding to specific cell surface receptors to recognize pathogens</p> Signup and view all the answers

    Which statement accurately describes acute inflammation in the context of periodontal disease?

    <p>It involves immune and inflammatory processes that can protect the tissue.</p> Signup and view all the answers

    Which bacterium is known for its gingipains that enable nutrient acquisition from gingival crevicular fluid (GCF)?

    <p>Porphyromonas gingivalis</p> Signup and view all the answers

    What is one of the mechanisms by which Aggregatibacter actinomycetemcomitans disrupts host defense?

    <p>Releasing leukotoxin</p> Signup and view all the answers

    Which of the following factors is associated with Treponema denticola's ability to disrupt host defenses?

    <p>Motility and invasion of tissues</p> Signup and view all the answers

    Tannerella forsythia is primarily recognized for producing which type of factors?

    <p>Proteases and apoptotic factors</p> Signup and view all the answers

    What role does the carbohydrate capsule of Porphyromonas gingivalis play in its pathogenicity?

    <p>Helps resist host defenses</p> Signup and view all the answers

    What is the primary role of Cytokine IL-1 in periodontitis?

    <p>Stimulates osteoclast activity</p> Signup and view all the answers

    Which cytokine is known for inhibiting bone formation?

    <p>Cytokine IL-6</p> Signup and view all the answers

    What is the effect of Prostaglandin E₂ (PGE₂) in periodontal disease?

    <p>Stimulates MMP secretion</p> Signup and view all the answers

    Which of the following is a major source of MMP enzymes in periodontal tissue?

    <p>Macrophages</p> Signup and view all the answers

    What happens when there is a disruption in the MMP-TIMP balance?

    <p>Excessive breakdown of connective tissue</p> Signup and view all the answers

    Which cytokine is primarily associated with connective tissue destruction?

    <p>Cytokine IL-8</p> Signup and view all the answers

    What is the primary action of MMP enzymes in periodontal tissues?

    <p>Induce breakdown of the collagen matrix</p> Signup and view all the answers

    Which mediator is critical for triggering osteoclasts to destroy bone?

    <p>Prostaglandin E₂ (PGE₂)</p> Signup and view all the answers

    Study Notes

    Bacteria Associated with Periodontal Disease

    • Porphyromonas gingivalis (P. gingivalis):

      • Capsule - can help resist some host defenses
      • Produces gingipains to enable the bacterium to use CPF as a source of nutrients
      • LPS (Lipopolysaccharide)
      • Haemagglutinins + platelet aggregators
      • Fimbrae and tissue invasion
      • Can suppress the early PMN (polymorphonuclear leukocytes) response

    • Aggregatibacter Actinomycetemcomitans (A.A):

      • Leukotoxin - can kill WBCs. Therefore, it interrupts host defenses
      • Produces proteases including collagenase
      • Can invade epithelial host cells

    • Tannerella forsythia

      • Proteases and apoptotic factors

    • Treponema denticola:

      • Adherence factors can bind to microorganisms
      • Mobile and can invade host tissues
      • Disrupts host defense
      • Delays wound healing by inhibiting migration of PMNs and degrading cytokines.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Description

    Explore the key bacterial players associated with periodontal disease, including their mechanisms of action and effects on host defenses. This quiz will cover species such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, highlighting their unique attributes. Test your knowledge on how these bacteria contribute to oral health issues.

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser