B5M3: Digestion and Absorption in the Small Intestine - BRS 2019
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Questions and Answers

Which enzyme in the intestinal brush border hydrolyzes oligosaccharides to glucose?

  • Maltase (correct)
  • Lactase
  • Sucrase
  • Trehalase

Which disaccharide is degraded by sucrase in the small intestine?

  • Lactose
  • Trehalose
  • Maltose
  • Sucrose (correct)

What is the primary sugar transport mechanism from the intestinal lumen into cells for glucose and galactose?

  • Active transport with K+
  • Symport with Na+ (SGLT1) (correct)
  • Passive diffusion
  • Facilitated diffusion (GLUT2)

What enzyme hydrolyzes 1,4-glycosidic bonds in starch to yield maltose and maltotriose?

<p>Amylase (D)</p> Signup and view all the answers

Which enzyme degrades lactose to glucose and galactose?

<p>Lactase (A)</p> Signup and view all the answers

How are glucose and galactose transported from the cell to blood after absorption in the small intestine?

<p>Facilitated diffusion (GLUT2) (D)</p> Signup and view all the answers

What is the fate of pancreatic proteases after their digestive work is complete?

<p>They degrade each other and are absorbed along with dietary proteins. (C)</p> Signup and view all the answers

How are the digestive products of protein absorbed?

<p>As amino acids, dipeptides, and tripeptides. (C)</p> Signup and view all the answers

Which type of amino acid transport occurs in the luminal membrane via Na+-dependent amino acid cotransport?

<p>Neutral amino acids. (A)</p> Signup and view all the answers

What happens to dipeptides and tripeptides after they are transported into intestinal cells?

<p>Cytoplasmic peptidases hydrolyze them to amino acids. (B)</p> Signup and view all the answers

What effect does low duodenal pH have on pancreatic lipase?

<p>Inactivates pancreatic lipase. (C)</p> Signup and view all the answers

How does ileal resection affect the bile acid pool?

<p>Depletes the bile acid pool because bile acids do not recirculate to the liver. (A)</p> Signup and view all the answers

What is the mechanism by which some strains of Escherichia coli cause diarrhea?

<p>Opening of Cl- channels in the luminal membrane (B)</p> Signup and view all the answers

How does the inclusion of glucose in oral rehydration solutions help counteract secretory losses?

<p>Stimulates absorption via Na+-glucose cotransport (A)</p> Signup and view all the answers

Which of the following should be asked when assessing a child with diarrhea according to the WHO history?

<p>Number of watery stools per day (D)</p> Signup and view all the answers

How should skin turgor be assessed to check for signs of dehydration in a child?

<p>Pinching and releasing the skin over the abdomen (D)</p> Signup and view all the answers

What is one of the signs indicating dehydration when offering water or ORS solution to a child with diarrhea?

<p>Child refuses to drink (A)</p> Signup and view all the answers

What is the main purpose of assessing pre-illness feeding practices and immunization history in a child with diarrhea?

<p>To identify potential causes and risk factors (B)</p> Signup and view all the answers

What is the recommended treatment for Asymptomatic cyst excretors infected with Entamoeba histolytica?

<p>Iodoquinol PO for 30-40 mg/kg/day for 20 days (C)</p> Signup and view all the answers

In high-income countries, when is judicious treatment of Shigella spp. recommended?

<p>For moderate to severe disease, immunocompromised patients, preventive measures in certain settings (C)</p> Signup and view all the answers

For which group does WHO recommend empiric antibiotics for dysentery caused by Shigella?

<p>For all children in developing countries (A)</p> Signup and view all the answers

What is the treatment duration with Tinidazole for mild to moderate intestinal disease caused by Entamoeba histolytica?

<p>5 days (C)</p> Signup and view all the answers

When should treatment for Shigella spp. be considered in high-income countries according to the text?

<p>For moderate to severe disease, immunocompromised patients, or to prevent/mitigate outbreaks in specific settings (D)</p> Signup and view all the answers

What should follow the initial treatment of Entamoeba histolytica infections to prevent relapse?

<p>Iodoquinol PO tid × 20 days (B)</p> Signup and view all the answers

What is the most appropriate indication for the adjunctive use of corticosteroids at the onset of anti-Pneumocystis therapy?

<p>Po2 less than 70 mm Hg (D)</p> Signup and view all the answers

Which prophylactic regimen is effective in preventing Pneumocystis pneumonia in patients with HIV?

<p>800 mg sulfamethoxazole and 160 mg trimethoprim once daily (A)</p> Signup and view all the answers

Why is trimethoprim-sulfamethoxazole considered as adjunctive therapy for incision and drainage of complicated MRSA abscesses?

<p>Increasing incidence of community-acquired MRSA infections (A)</p> Signup and view all the answers

Which infection is NOT effectively treated with a combination of doxycycline and streptomycin or gentamicin?

<p>Pneumocystis pneumonia (B)</p> Signup and view all the answers

What is a common feature of the lower prophylactic doses of trimethoprim-sulfamethoxazole?

<p>Less frequent adverse reactions (D)</p> Signup and view all the answers

In the treatment of brucellosis, what can be an effective substitute for the doxycycline combination?

<p>Trimethoprim-sulfamethoxazole (D)</p> Signup and view all the answers

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