Podcast
Questions and Answers
Both B and T lymphocytes undergo V(D)J recombination during their maturation processes.
Both B and T lymphocytes undergo V(D)J recombination during their maturation processes.
True
Mature B cells that pass central tolerance undergo further tolerance checks in the thymus.
Mature B cells that pass central tolerance undergo further tolerance checks in the thymus.
False
Plasma cells are a type of memory B cell that can rapidly respond to subsequent encounters with the same antigen.
Plasma cells are a type of memory B cell that can rapidly respond to subsequent encounters with the same antigen.
False
During B cell maturation, the completion of light chain rearrangement leads to the expression of surface immunoglobulin and the formation of immature B cells.
During B cell maturation, the completion of light chain rearrangement leads to the expression of surface immunoglobulin and the formation of immature B cells.
Signup and view all the answers
B cells require the assistance of T cells to become fully activated through the T-cell-dependent pathway.
B cells require the assistance of T cells to become fully activated through the T-cell-dependent pathway.
Signup and view all the answers
Memory B cells are short-lived cells that do not persist in the body after the immune response resolves.
Memory B cells are short-lived cells that do not persist in the body after the immune response resolves.
Signup and view all the answers
During B cell maturation, the rearrangement of the immunoglobulin heavy chain gene is mediated by the enzymes RAG1 and RAG2 through a process called V(D)J recombination.
During B cell maturation, the rearrangement of the immunoglobulin heavy chain gene is mediated by the enzymes RAG1 and RAG2 through a process called V(D)J recombination.
Signup and view all the answers
Activated T cells release cytokines, such as interleukin-4 (IL-4) and interleukin-21 (IL-21), which further promote B cell activation, proliferation, and differentiation.
Activated T cells release cytokines, such as interleukin-4 (IL-4) and interleukin-21 (IL-21), which further promote B cell activation, proliferation, and differentiation.
Signup and view all the answers
B cells can present antigens to cytotoxic T cells, which recognize and eliminate infected cells.
B cells can present antigens to cytotoxic T cells, which recognize and eliminate infected cells.
Signup and view all the answers
