Podcast
Questions and Answers
What factor is significantly influenced by the degree of crystallinity in drug delivery systems using CSNPs?
What factor is significantly influenced by the degree of crystallinity in drug delivery systems using CSNPs?
- Rate of drug absorption
- Particle size distribution
- Chemical properties of the polymer
- Hydrophilicity and hydrophobicity balance (correct)
Which of the following strategies increases the adsorption capacity of CSNPs?
Which of the following strategies increases the adsorption capacity of CSNPs?
- Decreasing the molecular weight
- Eliminating the sugar groups
- Reducing the number of amine groups
- Increasing the content of amine groups (correct)
How does surface roughness of nanoparticles affect their interaction with blood proteins?
How does surface roughness of nanoparticles affect their interaction with blood proteins?
- It decreases the binding efficiency.
- It increases concentration and interaction with proteins. (correct)
- It has no effect on protein interaction.
- It enhances drug absorption.
What is one consequence of the cationic nature of CSNPs in drug delivery applications?
What is one consequence of the cationic nature of CSNPs in drug delivery applications?
What mechanism primarily controls the drug release from CSNPs?
What mechanism primarily controls the drug release from CSNPs?
In the context of CSNPs, what effect does increasing molecular weight generally have?
In the context of CSNPs, what effect does increasing molecular weight generally have?
Which manufacturing method involves the cross-linking of chitosan chains for CSNP production?
Which manufacturing method involves the cross-linking of chitosan chains for CSNP production?
What is the influence of crystallinity on drug release from polymers?
What is the influence of crystallinity on drug release from polymers?
Which factor primarily determines the physicochemical properties of a polymer?
Which factor primarily determines the physicochemical properties of a polymer?
What primarily determines the breakdown of polymer structures in drug delivery systems?
What primarily determines the breakdown of polymer structures in drug delivery systems?
What condition describes a polymer when it is in a 'rubberlike' state?
What condition describes a polymer when it is in a 'rubberlike' state?
Which statement is true regarding the manufacturing methods of CSNPs?
Which statement is true regarding the manufacturing methods of CSNPs?
How does particle size impact the release profile of drugs from polymers?
How does particle size impact the release profile of drugs from polymers?
What is a common mechanism for polymer erosion?
What is a common mechanism for polymer erosion?
Which transition is described as a β relaxation transition in polymers?
Which transition is described as a β relaxation transition in polymers?
What effect do nano-fillers have on the glass transition temperature of polymers?
What effect do nano-fillers have on the glass transition temperature of polymers?
What is the primary characteristic of bi-phasic drug release?
What is the primary characteristic of bi-phasic drug release?
How does the diameter of CSNPs affect their behavior?
How does the diameter of CSNPs affect their behavior?
Which mechanism is NOT typically involved in drug release from polymer matrices?
Which mechanism is NOT typically involved in drug release from polymer matrices?
What factor influences the selection of a manufacturing method for CSNPs?
What factor influences the selection of a manufacturing method for CSNPs?
In which method is crosslinking primarily achieved by hydrogen bonding?
In which method is crosslinking primarily achieved by hydrogen bonding?
What impact does the modification of CSNPs have on drug release rates?
What impact does the modification of CSNPs have on drug release rates?
Which of the following mathematical models is NOT used for kinetic analysis of drug release?
Which of the following mathematical models is NOT used for kinetic analysis of drug release?
What is the primary effect of pH on drug release from CSNPs?
What is the primary effect of pH on drug release from CSNPs?
