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Questions and Answers
What distinguishes the anatomical origin of the parasympathetic nervous system?
What distinguishes the anatomical origin of the parasympathetic nervous system?
Where do the sympathetic ganglia primarily reside?
Where do the sympathetic ganglia primarily reside?
Which of the following regions significantly regulates autonomic nervous system activity?
Which of the following regions significantly regulates autonomic nervous system activity?
What is one key feature of both the somatic and autonomic nervous systems?
What is one key feature of both the somatic and autonomic nervous systems?
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Which type of neurons connect the central nervous system to the autonomic ganglia?
Which type of neurons connect the central nervous system to the autonomic ganglia?
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What is the primary role of the sympathetic nervous system during emergency situations?
What is the primary role of the sympathetic nervous system during emergency situations?
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Which of the following describes dual innervation?
Which of the following describes dual innervation?
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What is the effect of sympathetic stimulation on heart rate?
What is the effect of sympathetic stimulation on heart rate?
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During resting conditions, what is the dominant effect of the parasympathetic nervous system?
During resting conditions, what is the dominant effect of the parasympathetic nervous system?
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Which organ is exclusively innervated by sympathetic nerve fibers?
Which organ is exclusively innervated by sympathetic nerve fibers?
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What happens during sympathetic dominance of an organ?
What happens during sympathetic dominance of an organ?
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How do sympathetic and parasympathetic systems generally interact in terms of organ function?
How do sympathetic and parasympathetic systems generally interact in terms of organ function?
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What term describes the ongoing partial activity of both the sympathetic and parasympathetic nervous systems?
What term describes the ongoing partial activity of both the sympathetic and parasympathetic nervous systems?
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Which of the following statements about sweat glands is true?
Which of the following statements about sweat glands is true?
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What is the overall effect of parasympathetic activity on the digestive tract?
What is the overall effect of parasympathetic activity on the digestive tract?
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Study Notes
Autonomic Nervous System Overview
- A two-neuron system connects the central nervous system (CNS) to effector cells
- The first neuron starts in the CNS
- The synapse between neurons occurs outside the CNS, in a ganglion
- Neurons connecting the CNS to the ganglia are preganglionic neurons
- Neurons connecting ganglia to effector cells are postganglionic neurons
- The autonomic nervous system (ANS) is made up of two major divisions: sympathetic and parasympathetic
General Organization of Efferent Divisions
- The somatic nervous system uses a single neuron to connect to skeletal muscle.
- The autonomic nervous system uses two neurons to innervate smooth or cardiac muscle, glands, or GI neurons.
General Organization of the Autonomic Nervous System
- The ANS uses two neurons in series to connect the CNS to effector cells
- The first neuron in the pathway begins within the central nervous system.
- The synapse occurs outside the central nervous system in a cluster of nerve cells called an autonomic ganglion. The second neuron starts in this cluster (ganglion).
- The neurons leading from the CNS to the ganglion are called preganglionic neurons, and the neurons leading out of the ganglion to the effector cells are called postganglionic neurons
Location of Ganglia
- Sympathetic ganglia are located near the spinal cord, forming chains on either side
- Collateral ganglia (e.g., celiac, superior mesenteric, inferior mesenteric) are located in the abdominal cavity, closer to target organs.
- Parasympathetic ganglia are located within or very close to target organs
Regulation of Autonomic Nervous System Activity
- The autonomic nervous system activity is controlled by the hypothalamus and brainstem.
- Many variables, such as heart rate, blood pressure, gastrointestinal activity, body temperature, hunger, thirst, plasma volume, and plasma osmolarity, are monitored and regulated.
Two Important Features of Both Systems
- Most tissues receive dual innervation from both sympathetic and parasympathetic systems.
- Both systems are tonically active, meaning they exert some ongoing activity on tissues.
- An example of a tissue receiving only sympathetic innervation are blood vessels.
- Sweat glands are another example of a tissue receiving only sympathetic innervation.
Each System is Dominant Under Certain Conditions
- Sympathetic: Active during exercise, fight or flight situations, emergency reactions. Prepares the body for strenuous activity (e.g., increased blood flow to muscles).
- Parasympathetic: Active during quiet, resting conditions. Conserves energy and regulates basic body functions like digestion and urination.
Functions of the ANS
- The sympathetic and parasympathetic systems innervate most visceral organs (through dual innervation).
- The two systems often have opposing effects on the same organ (e.g., sympathetic increases heart rate, parasympathetic decreases).
Exceptions
- Innervated blood vessels receive only sympathetic nerve fibers.
- Sweat glands receive only sympathetic nerve fibers.
- Salivary glands are innervated by both divisions but responses are not antagonistic and depend on which division is more dominant.
Neurotransmitters
- Acetylcholine (ACh): Released at all preganglionic neurons in both sympathetic and parasympathetic divisions, all parasympathetic postganglionic neurons, and some sympathetic postganglionic neurons (to sweat glands).
- Norepinephrine (NE): Primary neurotransmitter of postganglionic sympathetic neurons.
- Epinephrine (Epi): Released by the adrenal medulla in response to stimulation by sympathetic fibers; plays an important role in fight or flight responses
Receptors
- Cholinergic receptors: Respond to acetylcholine. Nicotinic receptors and muscarinic receptors.
- Adrenergic receptors: Respond to norepinephrine and epinephrine. Alpha and beta subtypes (alpha 1, 2, beta 1, 2)
Drugs Acting on the Sympathetic and Parasympathetic Systems
- Sympathomimetics and sympatholytics: Drugs influencing sympathetic function.
- Parasympathomimetics and parasympatholytics: Drugs influencing parasympathetic function. Some examples are given.
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Description
Dive into the autonomic nervous system (ANS) and understand its organization, including the roles of preganglionic and postganglionic neurons. This quiz covers the two major divisions of the ANS: sympathetic and parasympathetic, and compares it to the somatic nervous system. Test your knowledge on how these systems interact with various effector cells.