Podcast
Questions and Answers
What is the main reason for the body to establish self-tolerance mechanisms?
What is the main reason for the body to establish self-tolerance mechanisms?
- To generate random specificities
- To cause autoimmune diseases
- To produce autoantibodies
- To avoid auto reactivity (correct)
Which autoimmune disease is mentioned as one of the earliest examples associated with the production of autoantibodies in a specific organ?
Which autoimmune disease is mentioned as one of the earliest examples associated with the production of autoantibodies in a specific organ?
- Hashimoto’s thyroiditis (correct)
- Lupus
- Type 1 diabetes
- Multiple sclerosis
What type of cells predominantly infiltrate the thyroid gland in Hashimoto’s thyroiditis?
What type of cells predominantly infiltrate the thyroid gland in Hashimoto’s thyroiditis?
- Mononuclear phagocytes (correct)
- Neutrophils
- Dendritic cells
- Eosinophils
What is a common outcome of Hashimoto's thyroiditis?
What is a common outcome of Hashimoto's thyroiditis?
Which demographic group is most commonly affected by Hashimoto’s thyroiditis?
Which demographic group is most commonly affected by Hashimoto’s thyroiditis?
What type of cells are notably found in extraordinary numbers within the infiltrated thyroid gland in Hashimoto's thyroiditis?
What type of cells are notably found in extraordinary numbers within the infiltrated thyroid gland in Hashimoto's thyroiditis?
What is a common feature of Hashimoto's disease involving thyroid follicles?
What is a common feature of Hashimoto's disease involving thyroid follicles?
Which condition shows almost complete destruction and shrinking of the thyroid gland?
Which condition shows almost complete destruction and shrinking of the thyroid gland?
Which antibodies are usually found in the serum of patients with Hashimoto's disease?
Which antibodies are usually found in the serum of patients with Hashimoto's disease?
What organ does the serum from patients with systemic lupus erythematosus react with?
What organ does the serum from patients with systemic lupus erythematosus react with?
What is a common shared characteristic of organ-specific autoimmune diseases?
What is a common shared characteristic of organ-specific autoimmune diseases?
What evidence suggests the role of genetic factors in autoimmune diseases?
What evidence suggests the role of genetic factors in autoimmune diseases?
