AUD Pharmacotherapy Goals and Treatment Strategies
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Questions and Answers

Match the goals of AUD pharmacotherapy with their descriptions:

Prevent/Treat withdrawal seizures = Use of long-acting benzodiazepines Prevent relapse = Use of Mu Opioid Antagonist Treat comorbid conditions = Management of additional mental health issues Prevent/treat withdrawal = Use of anticonvulsants

Match the medications to their specific usage:

Disulfiram (Antabuse) = Inhibit Aldehyde Dehydrogenase Naltrexone (ReVia, Trexan) = Prevent relapse Diazepam = Long-acting benzodiazepine for withdrawal Lamotrigine = Anticonvulsant for seizure prevention

Match the type of pharmacotherapy with its characteristics:

Disulfiram = Low patient compliance Naltrexone = Better than placebo Calcium Carbamide (Temposil) = Prolongs unpleasant effects of drinking Topiramate = Used for seizure prevention

Match the medications with their effects or actions:

<p>Naltrexone = Mu Opioid Antagonist Diazepam = Prevention of withdrawal seizures Lamotrigine = Anticonvulsant action Disulfiram = Inhibits aldehyde metabolism</p> Signup and view all the answers

Match the treatment goals with their respective medications:

<p>Prevent relapse = Naltrexone Prevent/treat withdrawal seizures = Diazepam Treat comorbid conditions = Various antidepressants Prevent withdrawal = Anticonvulsants</p> Signup and view all the answers

Study Notes

Goals of AUD Pharmacotherapy

  • Prevent and treat withdrawal symptoms, including seizures.
  • Prevent relapse.
  • Treat co-occurring conditions (comorbid).

Preventing/Treating Withdrawal Seizures

  • Long-acting benzodiazepines, such as diazepam, can be used.
  • Anticonvulsants like lamotrigine and topiramate are also effective.

Preventing Relapse

  • Disulfiram (Antabuse) and calcium carbimide (Temposil) inhibit aldehyde dehydrogenase, prolonging the unpleasant effects of alcohol consumption.
  • Patient compliance with disulfiram is often low.
  • Naltrexone (ReVia, Trexan) is a mu opioid antagonist.
  • Naltrexone is more effective than placebo.
  • Naltrexone injections may be more effective than oral versions.

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Description

This quiz covers the essential goals of pharmacotherapy for Alcohol Use Disorder (AUD), focusing on preventing and treating withdrawal symptoms, preventing relapse, and addressing co-occurring conditions. It includes details on medications such as benzodiazepines, anticonvulsants, disulfiram, and naltrexone, providing insights into their effectiveness and patient compliance issues.

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