Atropine Sulfate Flashcards

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the classification of Atropine Sulfate?

Parasympathetic blocker

Sympathomimetic

Vagolytic

All of the above (correct)

What are the therapeutic effects of Atropine?

Inhibits parasympathetic stimulation, decreases vagal tone, allows bronchioles to dilate.

What is the primary indication for Atropine?

Hemodynamically unstable bradycardia and pesticide poisoning.

Known hypersensitivity to Atropine is a contraindication.

True Signup and view all the answers

What are some cardiovascular side effects of Atropine?

Tachycardia, increased O2 demand, and bradycardia. Signup and view all the answers

What are the neurological side effects of Atropine?

Pupillary dilation, blurred vision, dizziness, confusion. Signup and view all the answers

What gastrointestinal side effects can be caused by Atropine?

Dry mouth, thirsty, difficulty swallowing. Signup and view all the answers

What administration method is used for Atropine in bradydysrhythmias?

IV Push: 0.5 mg every 3 to 5 minutes. Signup and view all the answers

What is the maximum single dose of Atropine for pediatrics in bradydysrhythmia?

0.5 mg for infant or child; 1 mg for adolescent. Signup and view all the answers

Signs of proper atropinization for pesticide poisoning include improved tidal volume or ______.

BVM compliance Signup and view all the answers

Neonates should be given Atropine for bradydysrhythmia.

False Signup and view all the answers

What are common household pesticides mentioned?

Flea and tick collars, ant and roach sprays, garden pesticides. Signup and view all the answers

Match the following terms with their definitions:

Atropine = Anticholinergic drug that blocks parasympathetic nerve impulses Vagal tone = The activity of the vagus nerve affecting heart rate Bradydysrhythmia = Abnormally slow heart rhythm Pesticide poisoning = Toxic reaction to chemicals used for pest control Signup and view all the answers

What is the dose range frequently published for Atropine?

0.5 to 1.0 mg. Signup and view all the answers

Paradoxical bradycardia may result from slow IV push of Atropine.

True Signup and view all the answers

Study Notes

Classification of Atropine Sulfate

Acts as a parasympathetic blocker, which inhibits parasympathetic functions.
Functions as a vagolytic agent by blocking vagal influences.
Classified as anticholinergic due to blocking acetylcholine at receptor sites.
Exhibits sympathomimetic properties, mimicking sympathetic nervous system activity.

Therapeutic Effects of Atropine

Inhibits parasympathetic stimulation by blocking acetylcholine receptors.
Increases heart rate by decreasing vagal tone and enhancing SA node automaticity and AV node conduction.
Facilitates bronchodilation and reduces secretions in the respiratory tract.

Indications for Atropine

Utilized for hemodynamically unstable bradycardia when pacing is unavailable.
Effective in cases of pesticide poisoning, particularly with organophosphates and carbamates.

Contraindications for Atropine

Should not be administered to individuals with known hypersensitivity to the drug.

Cardiovascular Side Effects of Atropine

May induce tachycardia and increase oxygen demand on the heart.
Possible complications include bradycardia and an increased incidence of Mobitz type II and third-degree heart block.

Neurological Side Effects of Atropine

Effects include pupil dilation, blurred vision, dizziness, confusion, restlessness, drowsiness, and headaches.
Possible symptoms such as photophobia or seizures can occur.

Respiratory Side Effects of Atropine

Can lead to the development of dry mucus plugs in the airways.

Gastrointestinal Side Effects of Atropine

Common side effects include dry mouth, excessive thirst, and difficulty swallowing.

Other Side Effects of Atropine

Results in hot, dry skin and can worsen pre-existing glaucoma conditions.

Administration of Atropine for Bradydysrhythmias

Adult IV push: 0.5 mg rapidly, can be repeated every 3 to 5 minutes to a maximum of 3 mg or 0.04 mg/kg.
For ET tube administration, deliver 2 to 2.5 times the IV dose, diluted with Normal Saline.

Administration of Atropine for Pesticide Poisoning

For adults, administer 2 mg every 5 to 15 minutes until asymptomatic, with no maximum dose.
For ET tube, deliver 4 mg diluted with Normal Saline every 5 minutes until therapeutic signs appear.

Pediatric Administration of Atropine for Bradydysrhythmias

Administer 0.02 mg/kg IV or IO, may repeat once after 5 minutes.
ET tube dosage is 0.04 mg/kg, not to be repeated.

Dosing Guidelines for Pediatrics

Minimum single dose is 0.1 mg.
Maximum single dose: 0.5 mg for infants/children, 1 mg for adolescents.

Pediatric Administration for Pesticide Poisoning

Administer 0.05 mg/kg IV, IM, or IO every 10 minutes until therapeutic results.
ET tube dosage is 0.1 mg/kg diluted in Normal Saline.

Dose Range for Atropine

Commonly published dose range is 0.5 to 1.0 mg.
Typical adult field dose for bradycardia is generally 0.5 mg.

Paradoxical Bradycardia

Can occur if atropine is administered as a slow IV push or in doses less than 0.5 mg in adults.

Cautionary Use Cases

Caution is needed in suspected acute myocardial infarction, as atropine can increase myocardial oxygen demand and risk injury.
Use with care in patients with infranodal heart blocks.

Neonates and Atropine

Atropine is contraindicated in neonates; epinephrine is preferred for bradydysrhythmias.

Signs of Proper Atropinization in Pesticide Poisoning

Improvement in tidal volume and bag-mask ventilator compliance.
Reduction in shortness of breath and wheezing.
Enhanced oxygen saturation (SpO2) and blood pressure.
Possible improvement in level of consciousness, with drying of skin and secretions.

Mnemonic for Signs of Excessive Atropine Administration

"Red as a beet, Dry as a bone, Hot as a pistol, Blind as a bat, Mad as a hatter."

Common Household Pesticides

Includes flea and tick collars, dips, and sprays.
Ant and roach sprays, over-the-counter bug bombs, and garden pesticides are common offenders.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Description

Test your knowledge of Atropine Sulfate with these flashcards covering its classification and therapeutic effects. Learn about this key medication's role as a parasympathetic blocker and its impact on heart rate and respiratory function.