Atrophy Overview Flashcards

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Questions and Answers

What is disuse atrophy?

Disuse atrophy is when something does not or cannot use a muscle.

What are some effects of atrophy?

  • Increase in type I fibers
  • Improvement in posture
  • Loss of cell proteins and organelles (correct)
  • Shrinkage of myofibers and muscle belly (correct)

Atrophy increases type I fibers and decreases type II fibers.

False (B)

What is a characteristic of myofiber size in disuse atrophy?

<p>Variable myofiber size (C)</p> Signup and view all the answers

How do age factors affect motor neurons?

<p>Motor neurons lose connections to some myofibers with age.</p> Signup and view all the answers

What happens to disconnected myofibers with age?

<p>They atrophy. (A)</p> Signup and view all the answers

Flashcards

Disuse Atrophy

When a muscle is not used for a long time, causing a loss of muscle mass and strength.

What happens to myofiber size in disuse atrophy?

A reduction in the size of muscle fibers due to inactivity.

What is disuse atrophy?

The process of losing muscle mass and strength due to lack of use.

Effects of atrophy?

Loss of cell proteins and organelles, leading to smaller muscle fibers.

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How do age factors affect motor neurons?

Motor neurons lose connections to some muscle fibers as we age, making them weaker and smaller.

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What happens to disconnected myofibers with age?

Muscle fibers that lose their connection to the motor neuron shrink and become weaker.

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Study Notes

Disuse Atrophy

  • Occurs when a muscle cannot be used, leading to decreased strength and size.

Atrophy Overview

  • Characterized by loss of cell proteins and organelles, essential for muscle function.
  • Involves the shrinkage of myofibers and overall muscle belly.
  • Often results from immobilization, limiting muscle activity.
  • Leads to a shift in muscle fiber composition: an increase in type II fibers and a decrease in type I fibers.

Myofiber Patterns

  • Disuse atrophy presents a variable size of myofibers, indicating inconsistent muscle loss.
  • De-innervation causes patchy myofiber shrinkage, as multiple muscle fibers are innervated by a single motor neuron.
  • Aging impacts motor neurons, causing them to disconnect from some myofibers.
  • Results in issues such as poor posture, weakness, and balance difficulties.
  • Atrophied myofibers that are disconnected fail to regenerate, while those still connected retain some regenerative capacity.

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