Atrial Fibrillation
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Questions and Answers

Which clotting factors does warfarin inhibit?

  • Factor IX
  • Factor II (correct)
  • Factor V
  • Factor VIII

What is the target International Normalized Ratio (INR) for outpatients on warfarin with atrial fibrillation (AF)?

  • 2.0-3.0 (correct)
  • 3.0-4.0
  • 4.0-5.0
  • 1.0-2.0

What can excessive anticoagulation with warfarin cause?

  • Arrhythmia
  • Hypertension
  • Bleeding (correct)
  • Thrombosis

Why is warfarin contraindicated in pregnancy?

<p>It has teratogenicity and fetal bleeding risk (D)</p> Signup and view all the answers

What is the purpose of a 'heparin bridge' at the start of warfarin therapy?

<p>To decrease the risk of thrombus formation (C)</p> Signup and view all the answers

Which vitamin K-dependent coagulation factors does warfarin inhibit?

<p>Factor II,VII, IX and X (D)</p> Signup and view all the answers

What is the main indication for using warfarin?

<p>All of the above (D)</p> Signup and view all the answers

Which test is used to monitor unfractionated heparin?

<p>Activated partial thromboplastin time (aPTT) (B)</p> Signup and view all the answers

Flashcards

Warfarin's effect on clotting factors

Warfarin inhibits vitamin K-dependent clotting factors, including Factors II, VII, IX, and X.

Warfarin INR target for AF

2.0 to 3.0 for outpatients with atrial fibrillation.

Warfarin's side effect related to bleeding risk.

Excessive warfarin can cause bleeding.

Warfarin's use in pregnancy

Warfarin is contraindicated during pregnancy due to teratogenicity/fetal bleeding risk.

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Heparin bridge purpose

To reduce the risk of blood clot formation while initiating warfarin therapy.

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Warfarin's primary use

Primary use is to prevent blood clots.

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Monitoring test for unfractionated heparin

Activated partial thromboplastin time (aPTT).

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Factor warfarin inhibits

Factors II, VII, IX, and X.

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