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Astringents in Wound Healing

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23 Questions

What is the effect of astringents on the environment of the affected area?

Making the area drier

What is the purpose of the protective layer formed by astringents on the injured mucosal membrane?

To prevent further irritation

Which type of medication is most likely to reduce cell volume in the affected area?

Astringents

What is a characteristic of astringents that helps to protect the injured mucosal membrane?

They form a thin protective layer

What is NOT a characteristic of astringents?

They reduce itching

What is the primary use of Astringents in anorectal disorders?

To temporarily relieve itching, irritation, and burning symptoms

Which of the following is NOT a type of medication used to treat anorectal disorders?

Keratolytics

What is the main difference between Anesthetics and Astringents?

Astringents are used to relieve itching, while Anesthetics are used to numb the area

Which of the following medications is used to relieve itching?

Antipruritics

What is the primary function of Analgesics in anorectal disorders?

To provide pain relief

What is the primary function of Astringents in the anorectal skin cells?

To promote coagulation of surface protein

Which of the following products is NOT related to the function of Astringents?

Keratolytics

What is the primary benefit of Astringents in the anorectal skin cells?

Protecting the underlying tissue

Which of the following products has a similar function to Astringents in the anorectal skin cells?

Anesthetics

What is the result of Astringents promoting coagulation of surface protein in the anorectal skin cells?

Protection of the underlying tissue

What type of medication is used to relieve pain in anorectal disorders?

Analgesics

Astringents are used to relieve itching in anorectal disorders.

False

What is the purpose of keratolytics in anorectal therapy?

To break down keratin, a protein that makes up skin cells

Local anesthetics are used to numb the area in anorectal disorders, reducing ____________________.

pain

What type of medication is used to reduce itching in anorectal disorders?

Antipruritics

Anesthetics and analgesics have the same function in anorectal disorders.

False

What is the purpose of corticosteroids in anorectal therapy?

To reduce inflammation

Match the following medications with their functions in anorectal disorders:

Astringents = Reduce cell volume Analgesics = Relieve pain Keratolytics = Break down keratin Antipruritics = Reduce itching

Study Notes

Astringents

  • Astringents decrease cell volume, creating a drier environment and reducing irritation.
  • They form a thin protective layer over the injured mucosal membrane to prevent further irritation.
  • Astringents are approved for the temporary relief of:
    • Itching symptoms
    • Irritation symptoms
    • Burning symptoms
    • Associated with anorectal disorders
  • Astringents promote coagulation of surface protein in anorectal skin cells to protect the underlying tissue.

Analgesics, Anesthetics, and Antipruritics

  • Menthol, juniper tar, and camphor are safe and effective for external perianal disorders when used correctly.
  • Camphor is mostly affected by accidental oral ingestion, especially in children.

Corticosteroids

  • 60% of topical anorectal agents contain corticosteroids, which act as vasoconstrictors and antipruritics.
  • Corticosteroids produce lysosomal membrane stabilization and antimitotic activity.
  • They are indicated for relieving itching, discomfort, and irritation, and for shrinking and decreasing swelling of hemorrhoidal tissues.

Precautions and Contraindications

  • Discontinue use and consult a doctor if symptoms do not subside or if redness, irritation, swelling, pain, or other symptoms develop or increase.
  • Extensive application of menthol to the trunk of the body can cause laryngospasm, dyspnea, and cyanosis, so it should be used sparingly.
  • Excessive scrubbing should be discouraged to minimize aggravation.

Pharmacologic Therapy

  • Local anesthetics, vasoconstrictors, protectants, astringents, keratolytics, analgesics, anesthetics, antipruritics, and corticosteroids are commonly used to relieve anorectal symptoms.

Learn about the role of astringents in wound healing, including their effects on cell volume and formation of a protective layer on injured mucosal membranes.

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