Asthma Pathophysiology Quiz
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Questions and Answers

What is the name for the resultant swelling caused by increased fluid due to increased vascular permeability?

  • Embolism
  • Ischemia
  • Thrombosis
  • Oedema (correct)
  • Which type of mediators are immediately released through degranulation when the cell membrane is broken?

  • Histamine
  • Newly synthesized mediators
  • Leukotrienes
  • Pre-formed mediators (correct)
  • What is the phase that lasts for about 24 hours and involves cellular infiltration attracted by chemotaxis?

  • Early phase
  • Acute phase
  • Late phase (correct)
  • Chronic phase
  • Which cells are specifically associated with the inflammatory process and have the ability to attract even more white blood cells to the affected area?

    <p>Cells associated with chemotaxis</p> Signup and view all the answers

    What is the name for the chronic inflammatory phase caused by repeated exposure to trigger factors, characterized by recruitment of eosinophils and excess mucus production?

    <p>Chronic phase</p> Signup and view all the answers

    What is inflammation?

    <p>A natural defense mechanism of body tissue to injury or irritation</p> Signup and view all the answers

    What can chronic inflammation lead to if not treated appropriately?

    <p>Irreversible tissue damage</p> Signup and view all the answers

    What are the characteristic signs of inflammation?

    <p>Heat, redness, swelling, pain/tenderness</p> Signup and view all the answers

    What happens to small blood vessels during inflammation?

    <p>They dilate to allow a greater blood supply to the affected area</p> Signup and view all the answers

    What term describes the abnormal response to harmless stimuli in some individuals?

    <p>Sensitization</p> Signup and view all the answers

    What are the classic symptoms of asthma?

    <p>Cough, Wheeze, Chest tightness, Breathlessness</p> Signup and view all the answers

    What contributes to the symptoms of asthma?

    <p>Smooth muscle dysfunction and airway inflammation</p> Signup and view all the answers

    What does smooth muscle dysfunction in asthma lead to?

    <p>Bronchoconstriction, Bronchial hyperreactivity, Inflammatory mediator release</p> Signup and view all the answers

    How should the diagnosis of asthma be based?

    <p>Symptoms, Past medical history, Family history, Physical examination, Investigations</p> Signup and view all the answers

    What can untreated smooth muscle dysfunction in asthma lead to?

    <p>Basement membrane thickening and airway remodeling</p> Signup and view all the answers

    What are key symptoms of asthma?

    <p>Cough, wheeze, breathlessness, and tightness across the chest</p> Signup and view all the answers

    What are common triggers of asthma?

    <p>Viral or bacterial infections, allergens, physical activity, stress, and certain drugs</p> Signup and view all the answers

    What role does family history play in asthma?

    <p>Children of mothers who smoked while pregnant are more likely to develop asthma</p> Signup and view all the answers

    What lung function test measures the maximum rate of air forcibly exhaled?

    <p>Peak expiratory flow (PEF)</p> Signup and view all the answers

    What indicates airway obstruction potentially due to asthma?

    <p>A measured PEF less than 80% of predicted</p> Signup and view all the answers

    Which factor can affect the metabolism of theophylline?

    <p>Age</p> Signup and view all the answers

    What are the two anticholinergic drugs in current use as bronchodilators?

    <p>Ipratropium bromide and oxitropium bromide</p> Signup and view all the answers

    What is the aim of asthma management?

    <p>To achieve maximum control of symptoms using the minimum amount of drug therapy</p> Signup and view all the answers

    What is the recommended frequency for reviewing patients with chronic asthma?

    <p>Every 3 to 6 months</p> Signup and view all the answers

    What is the classification of asthma control according to the text?

    <p>Few asthma symptoms, no sleep disturbance, no exercise limitation</p> Signup and view all the answers

    What is an important part of asthma management that is sometimes overlooked?

    <p>Regular review of patients and stepping down of therapy</p> Signup and view all the answers

    What should be in place for a patient who has had an asthma attack and is being discharged from the hospital?

    <p>Asthma self-management plan and correct inhaler technique</p> Signup and view all the answers

    What is the abbreviation for the Anti-inflammatory reliever (AIR) mentioned in the text?

    <p>MART</p> Signup and view all the answers

    What is the abbreviation for the Asthma Control Test mentioned in the text?

    <p>ACT</p> Signup and view all the answers

    What is the abbreviation for the Asthma Control Questionnaire mentioned in the text?

    <p>ACQ</p> Signup and view all the answers

    Which factor can affect the metabolism of theophylline?

    <p>Age, sex, body weight, and smoking</p> Signup and view all the answers

    What are the two anticholinergic drugs in current use as bronchodilators?

    <p>Ipratropium bromide (Atrovent) and oxitropium bromide (Oxivent)</p> Signup and view all the answers

    What is the abbreviation for the Asthma Control Test mentioned in the text?

    <p>ACT</p> Signup and view all the answers

    What is the classification of asthma control according to the text?

    <p>Controlled, partially controlled, uncontrolled</p> Signup and view all the answers

    What is the aim of asthma management?

    <p>To achieve maximum symptom control with minimal drug therapy</p> Signup and view all the answers

    What is an important part of asthma management that is sometimes overlooked?

    <p>Regular review of patients and stepping down of therapy</p> Signup and view all the answers

    What should be in place for a patient who has had an asthma attack and is being discharged from the hospital?

    <p>Discharge medications for 24 hours, correct inhaler technique, and an asthma self-management plan</p> Signup and view all the answers

    What is the recommended frequency for reviewing patients with chronic asthma?

    <p>Every 3 to 6 months</p> Signup and view all the answers

    What are common triggers of asthma?

    <p>Allergens, air pollution, and respiratory infections</p> Signup and view all the answers

    What term describes the abnormal response to harmless stimuli in some individuals?

    <p>Hyperresponsiveness</p> Signup and view all the answers

    Study Notes

    Understanding Asthma: Symptoms, Triggers, Diagnosis, and Family History

    • Key symptoms of asthma are cough, wheeze, breathlessness, and tightness across the chest
    • Children with asthma may present with a history of cough on exercise or at night, while adults may experience tiredness and heaviness in the chest
    • Common triggers of asthma include viral or bacterial infections, allergens, physical activity, stress, and certain drugs
    • Patients with asthma, particularly children, may have a history of recurrent upper and lower respiratory tract infections and allergies
    • Family history plays a role in asthma, and children of mothers who smoked while pregnant are more likely to develop asthma
    • Physical examination may not detect abnormalities, but it can help exclude other possible causes like chest infection or heart failure
    • Lung function tests, such as peak expiratory flow (PEF) and spirometry, are crucial for confirming the diagnosis of asthma
    • PEF is a simple, quick, and inexpensive lung-function test that measures the maximum rate of air forcibly exhaled
    • Spirometry provides more detailed information about the condition of the airways than PEF, measuring forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and FEV1/FVC ratio
    • A measured PEF less than 80% of predicted indicates airway obstruction, potentially due to asthma, but a diagnosis of asthma requires variability of 15% or more between two readings on separate occasions
    • Spirometry measures such as FVC, FEV1, and FEV1/FVC ratio are compared with predicted values and abnormal results can indicate disease or airway obstruction
    • Proper diagnosis of asthma involves comprehensive understanding of symptoms, triggers, family history, and accurate lung function tests.

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    Description

    Test your knowledge of asthma pathophysiology with this quiz. Explore the key components of inflammation and its role in asthma, as well as the different types of inflammation. Gain a deeper understanding of the pathophysiology of asthma and the key features of inflammation.

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