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Questions and Answers
What is the primary characteristic of chronic obstructive pulmonary disease (COPD)?
What is the primary characteristic of chronic obstructive pulmonary disease (COPD)?
Asthma can be completely cured with medication.
Asthma can be completely cured with medication.
False
List one common investigation used in the diagnosis of asthma.
List one common investigation used in the diagnosis of asthma.
Spirometry
In asthma, the immediate/early phase involves ______ and blood vessel dilation.
In asthma, the immediate/early phase involves ______ and blood vessel dilation.
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Match the diseases with their main characteristics:
Match the diseases with their main characteristics:
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Which class of drugs is commonly used in the management of asthma?
Which class of drugs is commonly used in the management of asthma?
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Smoking cessation is important for managing asthma.
Smoking cessation is important for managing asthma.
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Define FEV1.
Define FEV1.
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What is a common symptom associated with asthma?
What is a common symptom associated with asthma?
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Asthma can only be classified as intrinsic with no external triggers.
Asthma can only be classified as intrinsic with no external triggers.
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What are the two main types of asthma classified by their causes?
What are the two main types of asthma classified by their causes?
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The immediate effect of an allergen trigger in asthma involves the degranulation of ______ cells.
The immediate effect of an allergen trigger in asthma involves the degranulation of ______ cells.
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Match the following asthma characteristics to their definitions:
Match the following asthma characteristics to their definitions:
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What is the hallmark feature of late phase asthma response?
What is the hallmark feature of late phase asthma response?
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Salbutamol is used as part of the emergency treatment for severe asthma attacks.
Salbutamol is used as part of the emergency treatment for severe asthma attacks.
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In asthma, elevated ______ levels can indicate airway inflammation.
In asthma, elevated ______ levels can indicate airway inflammation.
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What is a common symptom of chronic bronchitis?
What is a common symptom of chronic bronchitis?
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Chronic bronchitis leads to a decrease in mucus production.
Chronic bronchitis leads to a decrease in mucus production.
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What primarily causes centriacinar emphysema?
What primarily causes centriacinar emphysema?
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In emphysema, the loss of __________ impairs lung function.
In emphysema, the loss of __________ impairs lung function.
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Match the type of emphysema with its cause:
Match the type of emphysema with its cause:
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Which immune cells are predominantly accumulated in the lungs during emphysema?
Which immune cells are predominantly accumulated in the lungs during emphysema?
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Thickening and scarring of airway tissue occurs in emphysema.
Thickening and scarring of airway tissue occurs in emphysema.
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What does the inflammation in airway cells during chronic bronchitis lead to?
What does the inflammation in airway cells during chronic bronchitis lead to?
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What is a primary symptom of COPD?
What is a primary symptom of COPD?
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The FEV1/FVC ratio is reduced in restrictive lung diseases.
The FEV1/FVC ratio is reduced in restrictive lung diseases.
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In ______ lung diseases, patients have difficulty exhaling air.
In ______ lung diseases, patients have difficulty exhaling air.
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Match the condition with its characteristic pattern in flow-volume loops:
Match the condition with its characteristic pattern in flow-volume loops:
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Which treatment is commonly recommended for COPD management?
Which treatment is commonly recommended for COPD management?
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Frequent infective exacerbations with purulent sputum are typical in asthma.
Frequent infective exacerbations with purulent sputum are typical in asthma.
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Study Notes
Asthma
- Asthma is a chronic disease affecting people of all ages.
- Characterized by airway inflammation, bronchoconstriction, and mucus production.
- Etiology: Extrinsic (exacerbated by environmental factors like allergens) and Intrinsic (related to internal factors).
- Pathophysiology: Involves IgE, mast cells, eosinophils, goblet cells, and basement membranes. Stages include immediate/early, late, and chronic.
- Investigations: Strong history and clinical signs, diurnal peak expiratory flow rate (PEFR) variability, bronchodilator reversibility test, bronchial challenge test (histamine).
COPD
- COPD is chronic obstructive pulmonary disease.
- Characterized by airflow limitation that's not fully reversible.
- Etiology: Smoking is the leading cause. Alpha-1 Antitrypsin Deficiency also plays a role.
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Pathophysiology: Emphysema (destruction of alveoli) and chronic bronchitis (inflammation of bronchioles) are common.
- Reversible and irreversible causes of airflow obstruction.
- Structural, functional, and immunological changes.
- Symptoms: Cough, shortness of breath (dyspnea), and sputum production.
- Investigations: Spirometry (reduced FEV1/FVC ratio), chest X-ray, arterial blood gases (ABGs).
- Treatment: Primarily focuses on managing symptoms, like smoking cessation and bronchodilators.
Lung Function Tests
- Obstructive: Difficulty exhaling air (e.g., asthma, COPD). -FEV1 is impacted
- Restrictive: Difficulty inhaling air (e.g., pulmonary fibrosis). -Impacted FVC
- Spirometry measures forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). A low FEV1/FVC ratio suggests obstructive disease.
- Flow-volume loops are helpful for determining obstructive and restrictive patterns. Obstructive = steeple patterns. Restrictive = reduction in overall volume.
Treatment
- Asthma treatment includes relievers (like salbutamol) and controllers (like inhaled corticosteroids). Severe cases might require hospitalization.
- COPD treatment primarily focuses on symptom management, including bronchodilators and smoking cessation programs.
Practice Questions
- There are practice questions provided for both asthma and COPD. There are questions on both topics.
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Description
This quiz explores the chronic diseases of Asthma and COPD, covering their etiology, pathophysiology, and methods of investigation. It is suitable for students learning about respiratory health and disease management. Test your understanding of the key concepts related to these conditions.