Chapter 11 - Drugs for Treating Asthma - Multiple Choice

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Questions and Answers

A patient presents with severe asthma exacerbation. Which of the following findings would be most indicative of a potentially fatal asthma attack, warranting immediate and aggressive intervention?

  • Peak expiratory flow (PEF) > 60% of predicted value with ability to speak in full sentences.
  • Quiet chest upon auscultation in the setting of significant dyspnea and altered level of consciousness. (correct)
  • Respiratory rate of 28 breaths/min with audible wheezing throughout all lung fields.
  • Heart rate of 110 beats/min with mild intercostal retractions.

A patient with a history of asthma is prescribed both albuterol and salmeterol. What is the primary rationale for prescribing these two medications in conjunction?

  • Albuterol prevents exercise-induced bronchospasm, while salmeterol controls nocturnal asthma symptoms.
  • Albuterol reduces airway inflammation, while salmeterol dilates the airways to improve airflow.
  • Albuterol is a short-acting beta-agonist for quick relief, while salmeterol is a long-acting beta-agonist for sustained bronchodilation. (correct)
  • Albuterol provides long-term asthma control, while salmeterol is used for immediate relief of acute symptoms.

A patient is prescribed fluticasone via inhaler for long-term asthma management. What is the most important instruction to provide to this patient regarding the use of this medication?

  • Administer the medication immediately before exercise to prevent exercise-induced bronchospasm.
  • Rinse the mouth with water after each use to prevent oral candidiasis (thrush). (correct)
  • Discontinue use of the inhaler if symptoms improve to avoid developing tolerance.
  • Use the inhaler only during asthma exacerbations to minimize potential side effects.

In the management of acute asthma exacerbations in the emergency department, when is the administration of systemic corticosteroids, such as prednisone, most appropriate?

<p>In patients with moderate to severe exacerbations to reduce airway inflammation and prevent relapse. (A)</p> Signup and view all the answers

A patient with a known history of asthma presents to the emergency department with acute respiratory distress. After initial assessment, the patient exhibits the following signs: use of accessory muscles, a respiratory rate of 30 breaths/min, heart rate of 125 beats/min, and difficulty speaking in full sentences. Which of the following interventions should be prioritized FIRST?

<p>Providing supplemental oxygen and administering a short-acting beta-agonist via nebulizer. (A)</p> Signup and view all the answers

Which of the following assessment findings in a patient experiencing an asthma exacerbation would be MOST concerning for impending respiratory failure?

<p>Absence of wheezing with decreased breath sounds and altered mental status. (D)</p> Signup and view all the answers

A 30-year-old patient with a history of well-controlled asthma presents to the clinic complaining of increased nighttime awakenings due to wheezing and coughing. The patient is currently using fluticasone daily. Which of the following would be the MOST appropriate next step in managing this patient's asthma?

<p>Add salmeterol to the patient's daily regimen. (D)</p> Signup and view all the answers

A patient with asthma is prescribed both fluticasone and salmeterol in a single inhaler (combination inhaler). What is the PRIMARY benefit of using a combination inhaler compared to using the two medications separately?

<p>Combination inhalers ensure better medication adherence and simplify the treatment regimen. (D)</p> Signup and view all the answers

A patient with a history of asthma presents with acute respiratory distress. Upon assessment, the patient is diaphoretic, using accessory muscles, and has a respiratory rate of 35 breaths/min. Auscultation reveals faint wheezing in all lung fields. What is the MOST appropriate initial intervention?

<p>Administer high-flow oxygen via a non-rebreather mask and initiate continuous nebulized albuterol. (B)</p> Signup and view all the answers

Which of the following statements BEST describes the role of ipratropium in the management of acute asthma exacerbations?

<p>Ipratropium is an anticholinergic medication that provides additive bronchodilation when used in combination with beta-agonists. (B)</p> Signup and view all the answers

A patient with a history of asthma is admitted to the hospital for an acute exacerbation. Despite receiving frequent nebulized albuterol treatments, the patient's peak expiratory flow (PEF) remains below 40% of their personal best. Which of the following medication adjustments would be MOST appropriate at this time?

<p>Add ipratropium to the nebulized albuterol treatments. (B)</p> Signup and view all the answers

When educating a patient about the appropriate use of a short-acting beta-agonist (SABA) inhaler, such as albuterol, which of the following instructions is MOST crucial to emphasize?

<p>Use the SABA inhaler as a rescue medication for acute symptoms and not as a substitute for long-term control medications. (B)</p> Signup and view all the answers

A patient with a long-standing history of asthma presents with progressively worsening symptoms, including increased frequency of albuterol use, nocturnal awakenings, and decreased exercise tolerance. Despite consistent use of inhaled corticosteroids, the patient's asthma remains poorly controlled. Which of the following strategies should be considered NEXT in the management of this patient's asthma?

<p>Add a long-acting beta-agonist (LABA) to the patient's inhaled corticosteroid regimen. (B)</p> Signup and view all the answers

A patient is prescribed a combination inhaler containing both fluticasone and salmeterol. Which of the following statements BEST explains the rationale for using these two medications together in a single inhaler?

<p>Fluticasone reduces airway inflammation, while salmeterol provides long-acting bronchodilation for asthma control. (D)</p> Signup and view all the answers

In a patient experiencing a severe asthma exacerbation, which of the following clinical findings would be MOST indicative of the need for intubation and mechanical ventilation?

<p>Altered mental status, decreased respiratory effort, and paradoxical chest movements. (B)</p> Signup and view all the answers

A child with a history of asthma is brought to the emergency department with acute respiratory distress. The child is using accessory muscles, has a respiratory rate of 40 breaths/min, and is only able to speak in short phrases. After initial treatment with nebulized albuterol and oxygen, there is minimal improvement in the child's symptoms. Which of the following interventions should be considered NEXT?

<p>Administer a systemic corticosteroid to reduce airway inflammation. (C)</p> Signup and view all the answers

A patient with a history of asthma and allergic rhinitis is undergoing evaluation for persistent and poorly controlled asthma symptoms. Which of the following diagnostic tests would be MOST helpful in identifying potential allergic triggers contributing to the patient's asthma?

<p>Allergy skin testing or in vitro IgE testing. (B)</p> Signup and view all the answers

What is the PRIMARY mechanism of action by which inhaled corticosteroids, such as fluticasone, help to control asthma symptoms?

<p>Suppressing the inflammatory response in the airways, thereby reducing airway hyperreactivity and mucus production. (C)</p> Signup and view all the answers

A patient with a history of asthma presents to the emergency department with acute respiratory distress. The patient's initial vital signs are: heart rate 130 beats/min, respiratory rate 35 breaths/min, oxygen saturation 88% on room air, and peak expiratory flow (PEF) 25% of predicted. After initial treatment with nebulized albuterol and ipratropium, the patient's PEF improves to 40% of predicted, but the other vital signs remain unchanged. What is the MOST appropriate next step in managing this patient?

<p>Administer a systemic corticosteroid (e.g., prednisone) to reduce airway inflammation. (C)</p> Signup and view all the answers

A patient with a history of asthma is being discharged from the hospital after an acute exacerbation. Which of the following components is MOST important to include in the patient's discharge plan to prevent future exacerbations?

<p>Written asthma action plan with instructions on medication use, symptom monitoring, and when to seek medical care. (C)</p> Signup and view all the answers

A 10-year-old child with a history of asthma is brought to the emergency department with severe respiratory distress. The child is cyanotic and has a decreased level of consciousness. Despite receiving initial treatment with oxygen and nebulized albuterol, the child's condition continues to deteriorate. Which of the following interventions should be prioritized FIRST?

<p>Prepare for endotracheal intubation and mechanical ventilation. (B)</p> Signup and view all the answers

A patient with a history of asthma is prescribed a long-acting beta-agonist (LABA) inhaler. Which of the following statements BEST describes the appropriate use of LABA inhalers in asthma management?

<p>LABA inhalers should be used in combination with an inhaled corticosteroid for long-term asthma control. (A)</p> Signup and view all the answers

A patient with a history of asthma and seasonal allergies presents to the clinic with increased asthma symptoms during the spring pollen season. In addition to adjusting the patient's asthma medications, which of the following strategies would be MOST appropriate to manage the patient's seasonal allergy-related asthma symptoms?

<p>Recommend the use of antihistamines and nasal corticosteroids to control allergic rhinitis symptoms. (C)</p> Signup and view all the answers

A patient is being treated in the emergency department for a severe asthma exacerbation. Despite aggressive treatment with oxygen, nebulized bronchodilators, and systemic corticosteroids, the patient's arterial blood gas (ABG) results show a pH of 7.25, PaCO2 of 55 mmHg, and PaO2 of 60 mmHg. Which of the following interventions should be considered NEXT?

<p>Prepare for endotracheal intubation and mechanical ventilation. (D)</p> Signup and view all the answers

A patient with a history of asthma is being taught how to use a peak flow meter to monitor their asthma control. Which of the following instructions is MOST important to emphasize when teaching the patient how to use a peak flow meter?

<p>Record the highest of three readings as their peak flow measurement. (A)</p> Signup and view all the answers

A patient with a history of asthma and frequent exacerbations is found to have persistent airflow limitation on pulmonary function testing, even when asymptomatic. Which of the following potential complications of long-standing asthma should be suspected?

<p>Irreversible airway remodeling. (A)</p> Signup and view all the answers

A patient with a history of asthma is being evaluated for possible exercise-induced bronchospasm (EIB). Which of the following strategies would be MOST effective in preventing EIB symptoms?

<p>Using a short-acting beta-agonist (SABA) inhaler 15-30 minutes before exercise. (C)</p> Signup and view all the answers

A patient with a history of asthma is prescribed a leukotriene receptor antagonist (LTRA), such as montelukast. Which of the following statements BEST describes the PRIMARY mechanism of action of LTRAs in asthma management?

<p>Blocking the effects of leukotrienes, which contribute to airway inflammation, bronchoconstriction, and mucus production. (B)</p> Signup and view all the answers

A patient with a history of severe asthma presents to the emergency department with acute respiratory distress. Despite receiving maximal medical therapy, the patient's condition continues to deteriorate, and they are now exhibiting signs of hypercapnic respiratory failure. Which of the following interventions should be considered as a LAST RESORT measure to improve the patient's respiratory status?

<p>Initiate extracorporeal membrane oxygenation (ECMO). (C)</p> Signup and view all the answers

A 65-year-old patient with a long-standing history of asthma and chronic obstructive pulmonary disease (COPD) presents to the clinic with worsening dyspnea and wheezing. How would you distinguish between asthma and COPD?

<p>Asthma is mostly reversible, while COPD is not fully reversible. (B)</p> Signup and view all the answers

A researcher is investigating the inflammatory mechanisms underlying asthma. Which of the following cell types is believed to play a CENTRAL role in initiating and perpetuating the allergic inflammatory cascade in asthma?

<p>Mast cells. (D)</p> Signup and view all the answers

A patient with a history of asthma and aspirin sensitivity (Samter's triad) is being evaluated for persistent nasal congestion and sinusitis. Which of the following treatment strategies should be AVOIDED in this patient due to the risk of exacerbating their asthma?

<p>Nonsteroidal anti-inflammatory drugs (NSAIDs). (D)</p> Signup and view all the answers

A patient with a history of brittle asthma is started on a low dose of theophylline. Which of the following statements BEST describes the therapeutic goals and monitoring requirements for theophylline in asthma management?

<p>Theophylline is used as an adjunct to inhaled corticosteroids and beta-agonists in patients with severe asthma and requires monitoring of serum theophylline levels. (C)</p> Signup and view all the answers

A patient with a history of severe, uncontrolled asthma is being considered for bronchial thermoplasty. Which of the following statements BEST describes the mechanism of action of bronchial thermoplasty in asthma management?

<p>Bronchial thermoplasty involves the delivery of controlled radiofrequency energy to the airway walls to reduce airway smooth muscle mass. (C)</p> Signup and view all the answers

A patient with a history of asthma and gastroesophageal reflux disease (GERD) reports that their asthma symptoms worsen after meals, especially when lying down. Which of the following strategies would be MOST appropriate to manage this patient's asthma-related to GERD?

<p>Prescribe a proton pump inhibitor (PPI) to reduce gastric acid production and improve GERD symptoms. (D)</p> Signup and view all the answers

A patient with a history of asthma and obesity is being evaluated for persistent and poorly controlled asthma symptoms. Which of the following factors related to obesity may contribute to the patient's asthma severity?

<p>Diaphragmatic elevation, reduced chest wall compliance, and increased systemic inflammation. (C)</p> Signup and view all the answers

A patient is experiencing an asthma exacerbation and presents with a heart rate of 130 beats/min, respiratory rate of 30 breaths/min, and difficulty speaking in full sentences. According to the criteria associated with a potentially fatal asthma attack, which of the following additional signs would MOST strongly suggest impending respiratory failure?

<p>A 'quiet chest' upon auscultation despite obvious respiratory distress. (C)</p> Signup and view all the answers

A patient with a history of asthma is prescribed albuterol (ProAir) for PRN use. Which statement indicates the patient understands the appropriate use of this medication?

<p>&quot;I should use this inhaler as the first line of defense to relax my airway muscles during an asthma attack or before exercise.&quot; (A)</p> Signup and view all the answers

A patient with persistent asthma symptoms is prescribed both fluticasone propionate and salmeterol in a combination inhaler. What is the MOST important aspect of patient education regarding this medication?

<p>Explaining the distinct roles of each medication, with fluticasone reducing inflammation and salmeterol providing bronchodilation, for long-term control. (D)</p> Signup and view all the answers

Following the administration of initial therapies for an acute asthma exacerbation, which finding would be MOST indicative of the need to escalate care and consider adjunctive therapies such as magnesium sulfate or heliox?

<p>Persistent use of accessory muscles and a PEF of less than 40% of predicted value. (B)</p> Signup and view all the answers

A patient with a history of asthma and documented allergies presents to the emergency department with an acute asthma exacerbation. The patient received appropriate doses of albuterol and ipratropium via nebulizer without significant improvement. What is the next appropriate step?

<p>Evaluate the patient for signs and symptoms of impending respiratory failure and prepare for possible intubation. (B)</p> Signup and view all the answers

Which of the following findings in a patient with an acute asthma exacerbation would warrant HIGH consideration for endotracheal intubation and mechanical ventilation?

<p>Progressive hypercapnia with a declining level of consciousness despite maximal medical therapy. (D)</p> Signup and view all the answers

A patient with a known history of asthma presents to the emergency department complaining of acute shortness of breath. The patient is speaking in short sentences, has audible wheezing, and is using accessory muscles to breathe. Which of the following interventions should be implemented FIRST?

<p>Administer high-flow oxygen and nebulized bronchodilators, such as albuterol and ipratropium. (A)</p> Signup and view all the answers

Which of the following is the MOST concerning sign in a patient experiencing an acute asthma exacerbation?

<p>A 'quiet chest' on auscultation. (C)</p> Signup and view all the answers

A 32-year-old patient with a history of mild intermittent asthma typically well-managed with PRN albuterol presents to the clinic complaining of increased frequency of asthma symptoms, including nocturnal cough and wheezing, over the past month. She denies any recent infections or changes in her environment. What is the MOST appropriate next step in managing this patient?

<p>Initiate daily inhaled corticosteroid therapy, such as fluticasone, to address underlying airway inflammation. (C)</p> Signup and view all the answers

A patient with a history of asthma is prescribed salmeterol via inhaler. Which of the following instructions is MOST important to emphasize when educating the patient about this medication?

<p>Salmeterol should be taken every day, even when feeling well, to prevent asthma symptoms. (B)</p> Signup and view all the answers

A patient with a known history of asthma presents to the emergency department with acute respiratory distress. After initial assessment, the patient exhibits the following signs: use of accessory muscles, a respiratory rate of 32 breaths/min, a heart rate of 125 beats/min, and peak expiratory flow (PEF) at 30% of predicted. Despite initial treatment with nebulized albuterol, the patient shows minimal improvement. Which of the following interventions should be prioritized NEXT?

<p>Administer systemic corticosteroids, such as intravenous methylprednisolone. (C)</p> Signup and view all the answers

What is the PRIMARY mechanism of action of ipratropium in acute asthma exacerbations?

<p>Ipratropium blocks muscarinic receptors in the airways, leading to bronchodilation and reduced mucus production. (A)</p> Signup and view all the answers

A patient with a long-standing history of asthma presents with progressively worsening symptoms, including increased frequency of albuterol use, nocturnal awakenings, and decreased exercise tolerance. The patient has been consistently using inhaled corticosteroids as prescribed. Which of the following strategies should be considered NEXT to optimize asthma management?

<p>Add a long-acting beta-agonist (LABA), such as salmeterol, to the inhaled corticosteroid regimen. (B)</p> Signup and view all the answers

Which of the following statements BEST explains the rationale for using fluticasone and salmeterol together in a single inhaler?

<p>Fluticasone and salmeterol have synergistic effects, reducing airway inflammation and promoting bronchodilation. (D)</p> Signup and view all the answers

A child with a history of asthma presents to the emergency department with acute respiratory distress. After initial treatment with nebulized albuterol and oxygen, there is minimal improvement in the child's symptoms. The child is using accessory muscles, has a respiratory rate of 40 breaths/min, and is only able to speak in short phrases. What intervention should be considered NEXT?

<p>Administer intravenous corticosteroids (e.g., methylprednisolone) to reduce airway inflammation. (C)</p> Signup and view all the answers

A patient with a history of asthma presents to the emergency department with acute respiratory distress. The patient's initial vital signs are: heart rate 130 beats/min, respiratory rate 35 breaths/min, oxygen saturation 88% on room air, and peak expiratory flow (PEF) 25% of predicted. After initial treatment with nebulized albuterol and ipratropium, the patient's PEF improves to 40% of predicted, but the other vital signs remain unchanged. What is the MOST appropriate next step?

<p>Administer systemic corticosteroids, such as intravenous methylprednisolone. (B)</p> Signup and view all the answers

A patient with a long-standing history of asthma and chronic obstructive pulmonary disease (COPD) presents to the clinic with worsening dyspnea and wheezing. Which finding is MOST indicative of diagnosis of asthma?

<p>Spirometry demonstrating post-bronchodilator reversibility. (D)</p> Signup and view all the answers

A patient with a history of asthma and aspirin sensitivity (Samter's triad) is being evaluated for persistent nasal congestion and sinusitis. What treatment strategies should be AVOIDED in this patient due to the risk of exacerbating their asthma?

<p>Aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). (A)</p> Signup and view all the answers

What statement BEST describes the therapeutic goals and monitoring requirements for theophylline in asthma management?

<p>Theophylline is a bronchodilator with a narrow therapeutic index, requiring regular monitoring of serum levels to prevent toxicity. (B)</p> Signup and view all the answers

A 10-year-old child with a history of asthma is in the emergency department with severe respiratory distress. The child is cyanotic and has a decreased level of consciousness. Despite treatment with oxygen and nebulized albuterol, the child's condition continues to deteriorate. Of the interventions below, which should be prioritized?

<p>Prepare for endotracheal intubation and mechanical ventilation. (D)</p> Signup and view all the answers

A researcher is investigating the inflammatory mechanisms underlying asthma. Which cell type is the MOST responsible for perpetuating the allergic inflammatory cascade in asthma?

<p>T lymphocytes (C)</p> Signup and view all the answers

A patient with a history of asthma is being taught how to use a peak flow meter to monitor their asthma control. Which instruction is MOST important to emphasize when teaching the patient how to use a peak flow meter?

<p>Take several deep breaths then forcefully exhale as quickly and completely as possible into the device, and record the highest of three attempts. (A)</p> Signup and view all the answers

A patient experiencing severe asthma exacerbation demonstrates a sudden absence of wheezing after initial bronchodilator treatment. While diminished breath sounds are noted bilaterally, the patient's respiratory rate remains elevated at 35 breaths/min, and they exhibit increased agitation. Which of the following is the MOST appropriate interpretation of these findings?

<p>The absence of wheezing and diminished breath sounds suggest worsening airflow obstruction and impending respiratory failure. (B)</p> Signup and view all the answers

A patient receiving albuterol via nebulizer complains of palpitations and tremors. Their heart rate increases from 90 to 120 beats/min. Which of the following mechanisms BEST explains these adverse effects of albuterol?

<p>Stimulation of beta-1 adrenergic receptors leading to increased heart rate and contractility. (B)</p> Signup and view all the answers

A patient with a history of asthma and allergic rhinitis is undergoing evaluation to determine triggers, and has a negative skin test. What is the MOST appropriate next step in evaluating hypersensitivity triggers?

<p>Obtain specific IgE testing (RAST) for common aeroallergens. (B)</p> Signup and view all the answers

A patient with asthma is being treated with omalizumab. What is the primary rationale for using this medication in asthma management?

<p>To prevent IgE from binding to mast cells, thereby reducing allergic inflammation. (D)</p> Signup and view all the answers

In a patient with severe asthma exacerbation unresponsive to initial bronchodilator therapy, which of the following arterial blood gas (ABG) findings would be MOST concerning for impending respiratory collapse and the need for mechanical ventilation?

<p>pH 7.20, PaCO2 60 mmHg, PaO2 55 mmHg. (A)</p> Signup and view all the answers

What is the underlying mechanism by which ipratropium bromide leads to bronchodilation in the treatment of asthma?

<p>Antagonism of muscarinic receptors, reducing vagal tone and bronchoconstriction. (A)</p> Signup and view all the answers

A patient with a history of severe asthma is prescribed a low dose of theophylline. Which statement about theophylline is correct?

<p>Theophylline is used as an adjunct to inhaled corticosteroids and beta-agonists in severe asthma. (A)</p> Signup and view all the answers

A patient with a history of aspirin-exacerbated respiratory disease (AERD) requires treatment for nasal polyposis. Which treatment is MOST appropriate?

<p>Montelukast to reduce leukotriene-mediated inflammation. (D)</p> Signup and view all the answers

A patient with a long history of poorly controlled asthma develops signs of Cushing's syndrome. Which medication is the MOST likely cause?

<p>Oral prednisone. (B)</p> Signup and view all the answers

A patient uses albuterol for exercise-induced asthma but finds it less effective over time. Which is the BEST approach?

<p>Add montelukast daily. (C)</p> Signup and view all the answers

Which finding is MOST indicative of hypercapnic respiratory failure in a patient experiencing a severe asthma exacerbation?

<p>A decreased level of consciousness and confusion. (A)</p> Signup and view all the answers

A patient with a history of asthma and obesity is being evaluated for persistent symptoms despite adherence to their prescribed medications. What is the MOST likely reason for the patient experiencing persistent and poorly controlled asthma symptoms?

<p>Down regulation of beta-2 receptors. (D)</p> Signup and view all the answers

A patient receiving high-dose inhaled corticosteroids for asthma develops oral candidiasis (thrush). Which of the following is the BEST approach for managing this complication?

<p>Add an oral antifungal medication and rinse the mouth after using the inhaler. (C)</p> Signup and view all the answers

A patient with a history of asthma and gastroesophageal reflux disease (GERD) reports increased asthma symptoms, especially at night. Which intervention is MOST appropriate?

<p>Initiating a proton pump inhibitor (PPI) and advising the patient to elevate the head of their bed. (B)</p> Signup and view all the answers

A patient presents to the emergency department with an asthma exacerbation. Initial treatment includes oxygen, nebulized albuterol/ipratropium, and IV corticosteroids. Despite these interventions, the patient's peak expiratory flow (PEF) remains below 40% of predicted. Which of the following interventions should be prioritized?

<p>Administering intravenous magnesium sulfate. (D)</p> Signup and view all the answers

A patient with severe persistent asthma is being considered for bronchial thermoplasty. Which of the following statements BEST describes the mechanism of action of bronchial thermoplasty in asthma management?

<p>It reduces airway smooth muscle mass, decreasing airway hyperresponsiveness. (B)</p> Signup and view all the answers

A patient with a well-documented history of exercise-induced bronchospasm (EIB) wants to start a new high-intensity workout routine. What's the MOST appropriate prophylactic strategy?

<p>Taking a leukotriene receptor antagonist (LTRA) daily. (D)</p> Signup and view all the answers

Which finding is the MOST concerning for acute respiratory failure in a patient experiencing a severe asthma exacerbation?

<p>Decreased level of consciousness and lethargy. (A)</p> Signup and view all the answers

A patient with unstable asthma and frequent exacerbations is started on a new medication. Which finding would warrant immediate discontinuation of the medication??

<p>Significant mood changes, including agitation and depression. (B)</p> Signup and view all the answers

An adult with a history of allergic asthma has persistent symptoms despite adherence to inhaled corticosteroids and a long-acting beta-agonist. What is the BEST next step?

<p>Start omalizumab (anti-IgE therapy). (B)</p> Signup and view all the answers

A patient with asthma is prescribed a combination inhaler containing fluticasone and salmeterol. Which of the following is the MOST appropriate counseling point to emphasize?

<p>Rinse your mouth with water after each use to prevent oral thrush. (D)</p> Signup and view all the answers

What is the MOST appropriate strategy for managing a patient with a history of brittle asthma who presents with frequent, severe exacerbations despite high-dose inhaled corticosteroids and long-acting beta-agonists?

<p>Consider anti-IgE therapy with omalizumab or bronchial thermoplasty. (B)</p> Signup and view all the answers

A 60-year-old former smoker with a history of both asthma and COPD presents with increasing dyspnea. Which finding would MOST strongly suggest that the patient's current symptoms are primarily due to asthma?

<p>A significant bronchodilator response on spirometry. (D)</p> Signup and view all the answers

A patient with a history of severe allergic asthma is undergoing evaluation to determine triggers. The skin test result is negative. What is the next appropriate step?

<p>Obtain specific IgE testing (RAST) for common aeroallergens. (B)</p> Signup and view all the answers

A patient with asthma is prescribed a long-acting beta-agonist (LABA) inhaler. What is the MOST important counseling point to emphasize?

<p>Use this inhaler every day, even when you feel well, to prevent asthma symptoms. (C)</p> Signup and view all the answers

A patient receiving albuterol via nebulizer complains of palpitations and tremors. The patient's heart rate increases from 80 to 120 beats/min. What is the BEST course of action?

<p>Reduce the dose of albuterol and monitor the patient's heart rate closely. (C)</p> Signup and view all the answers

A patient with a history of asthma and allergic rhinitis is undergoing evaluation. What diagnostic test is MOST helpful in identifying potential allergic triggers?

<p>Allergy skin testing or specific IgE testing (RAST). (B)</p> Signup and view all the answers

Which treatment is MOST appropriate for a patient with a known history of asthma who presents with acute shortness of breath, audible wheezing, and is using accessory muscles to breathe?

<p>Administering oxygen and initiating nebulized albuterol treatments. (C)</p> Signup and view all the answers

A patient presents to the emergency department with an asthma exacerbation. After initial treatment with oxygen and nebulized albuterol, the patient's oxygen saturation remains at 88% on room air. What is the MOST appropriate next step?

<p>Increase the oxygen flow rate and administer ipratropium via nebulizer. (B)</p> Signup and view all the answers

A patient has severe asthma exacerbation and continues to deteriorate despite maximal medical therapy. As a last resort, which intervention should be considered to improve the patient's respiratory status?

<p>Initiate neuromuscular blockade and mechanical ventilation. (D)</p> Signup and view all the answers

Which of the following is the MOST concerning sign for impending respiratory failure in a patient experiencing an acute asthma exacerbation?

<p>A decreased level of consciousness and confusion. (C)</p> Signup and view all the answers

A child with a history of asthma is brought to the emergency department with severe respiratory distress. The interventions below are all valid; however, which should be prioritized FIRST?

<p>Administer supplemental oxygen to maintain oxygen saturation above 90%. (A)</p> Signup and view all the answers

A patient presents with asthma exacerbation. Which of the following findings indicates a potentially fatal asthma attack?

<p>Heart rate &gt;120 beats/min or increasing, respiratory rate &gt;25-30 breaths/min, use of accessory muscles. (C)</p> Signup and view all the answers

A patient is prescribed both fluticasone propionate and salmeterol in a combination inhaler. What is the MOST important aspect of patient education regarding this medication?

<p>Rinse the mouth out with water afterward to decrease the risk of developing thrush. (C)</p> Signup and view all the answers

A patient with a history of asthma presents to the emergency department. Upon assessment, which finding is the MOST indicative of a potentially fatal asthma attack?

<p>Altered level of consciousness and a quiet chest despite reported dyspnea. (A)</p> Signup and view all the answers

A patient with asthma is prescribed both albuterol and ipratropium via nebulizer for acute exacerbations. What is the PRIMARY reason for combining these two medications?

<p>To target different receptors in the airway, providing synergistic bronchodilation. (C)</p> Signup and view all the answers

A patient is prescribed fluticasone via inhaler for long-term asthma management. Which of the following statements demonstrates an understanding of the MOST critical aspect of using this medication?

<p>&quot;I need to rinse my mouth out with water after each use to prevent oral thrush.&quot; (A)</p> Signup and view all the answers

In the management of acute asthma exacerbations, when is the administration of systemic corticosteroids, such as prednisone, MOST crucial?

<p>When the patient's symptoms do not respond adequately to initial bronchodilator therapy. (A)</p> Signup and view all the answers

A patient with a known history of asthma presents to the emergency department with acute respiratory distress. The patient is using accessory muscles, respiratory rate is 30 breaths/min, heart rate is 125 beats/min, and has difficulty speaking in full sentences. Which intervention should be prioritized FIRST?

<p>Administer oxygen and a short-acting beta-agonist via nebulizer. (A)</p> Signup and view all the answers

Which assessment finding in a patient experiencing an asthma exacerbation would be MOST concerning for impending respiratory failure?

<p>The presence of paradoxical chest wall movement and decreased level of consciousness. (B)</p> Signup and view all the answers

A patient with a history of well-controlled asthma presents to the clinic complaining of increased nighttime awakenings due to wheezing and coughing. The patient is currently using fluticasone daily. What is the MOST appropriate next step?

<p>Add a long-acting beta-agonist (LABA) to the patient's current regimen. (C)</p> Signup and view all the answers

A patient is prescribed both fluticasone and salmeterol in a single inhaler (combination inhaler). What is the PRIMARY benefit of using a combination inhaler compared to using the two medications separately?

<p>It improves adherence to the prescribed regimen by simplifying the administration. (D)</p> Signup and view all the answers

A patient with a history of asthma presents with acute respiratory distress. The patient is diaphoretic, using accessory muscles, and has a respiratory rate of 35 breaths/min. Auscultation reveals faint wheezing in all lung fields. What is the MOST appropriate initial intervention?

<p>Administer oxygen and a short-acting beta-agonist via nebulizer. (B)</p> Signup and view all the answers

A patient with a history of asthma and frequent exacerbations is found to have persistent airflow limitation on pulmonary function testing, even when asymptomatic. Which potential complication of long-standing asthma should be suspected?

<p>Airway remodeling with irreversible changes. (A)</p> Signup and view all the answers

A patient with a history of asthma is prescribed a leukotriene receptor antagonist (LTRA), such as montelukast. Which statement BEST describes the PRIMARY mechanism of action of LTRAs in asthma management?

<p>They block the effects of leukotrienes, reducing airway inflammation and bronchoconstriction. (C)</p> Signup and view all the answers

A patient with a history of severe asthma presents to the emergency department with acute respiratory distress. The patient shows signs of hypercapnic respiratory failure, despite maximal medical therapy. Which intervention should be a LAST RESORT?

<p>Extracorporeal membrane oxygenation (ECMO). (C)</p> Signup and view all the answers

A patient with a history of asthma and aspirin sensitivity (Samter's triad) is being evaluated for persistent nasal congestion and sinusitis. Which treatment strategies should be AVOIDED?

<p>Nonsteroidal anti-inflammatory drugs (NSAIDs) (A)</p> Signup and view all the answers

A patient with a history of brittle asthma is started on a low dose of theophylline. Which statement BEST describes the therapeutic goals and monitoring requirements for theophylline in asthma management?

<p>Theophylline is used as an add-on therapy to improve asthma control, with close monitoring of serum levels due to its narrow therapeutic index. (C)</p> Signup and view all the answers

A patient with a history of severe, uncontrolled asthma is being considered for bronchial thermoplasty. Which statement BEST describes the mechanism of action of bronchial thermoplasty in asthma management?

<p>It delivers controlled radiofrequency energy to the airway walls to reduce airway smooth muscle mass. (D)</p> Signup and view all the answers

A patient with a history of asthma and gastroesophageal reflux disease (GERD) reports that their asthma symptoms worsen after meals, especially when lying down. What strategies would be MOST appropriate to manage this patient's asthma-related to GERD?

<p>Prescribing a proton pump inhibitor (PPI) and advising the patient to avoid lying down after meals. (C)</p> Signup and view all the answers

A patient experiencing an asthma exacerbation presents with a heart rate of 130 beats/min, a respiratory rate of 30 breaths/min, and difficulty speaking in full sentences. Which additional sign would MOST strongly suggest impending respiratory failure?

<p>A decreased level of consciousness and paradoxical chest wall movement. (B)</p> Signup and view all the answers

Flashcards

Short-acting beta-agonists

A class of asthma rescue drugs that includes albuterol and works by relaxing airway muscles for quick relief.

Anticholinergics (for asthma)

An asthma rescue drug that combats bronchoconstriction by blocking acetylcholine receptors, leading to airway relaxation.

DuoNeb

Asthma drugs: ipratropium and albuterol

Systemic Corticosteroids

Medication such as prednisone to help reduce inflammation

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Inhaled Corticosteroids (long-term)

Drugs that reduce airway inflammation over time, such as Fluticasone.

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Long-acting beta-adrenergic agonists

A long-term asthma control medication that relaxes airway muscles for extended periods.

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Asthma

A chronic inflammatory disease of the airways. Causes bronchoconstriction

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Use of accessory muscles of respiration

Using muscles in the neck and chest to breathe.

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Heart rate >120

A heart rate exceeding 120 beats/min or an increasing heart rate can be an indicator of a severe asthma attack

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Respiratory Rate >25-30

Breathing rate exceeding 25-30 breaths/min indicates respiratory distress.

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Difficulty Speaking

Struggling to speak due to shortness of breath or fatigue.

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Altered Level of Consciousness

Changes in awareness or responsiveness.

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Quiet Chest

Absence of normal breath sounds.

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Diaphoresis

Excessive sweating.

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Inability to lie supine

Inability to breathe laying horizontally

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Rapid Onset Asthma

A potentially fatal asthma attack can occur rapidly, with minimal warning, leading to severe respiratory compromise.

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Importance of Early Intervention

Even in severe asthma cases, early recognition and aggressive treatment can potentially prevent fatal outcomes.

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Variable Airflow Obstruction

Measurements of airflow obstruction, such as peak expiratory flow, worsen variably before presentation in asthma exacerbations.

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Peak Expiratory Flow (PEF)

A diagnostic sign of a fatal asthma attack includes a peak expiratory flow (PEF) measurement indicating severely limited airflow.

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Study Notes

  • Asthma involves diffuse airway inflammation from various triggers, leading to bronchoconstriction that is partially or fully reversible.
  • Asthma symptoms include dyspnea, chest tightness, cough, and wheezing.
  • Emergency department-treated asthma exacerbations typically resolve within 2 hours.
  • Symptom onset, duration, and airflow obstruction worsening vary, typically occurring over several hours.
  • Early recognition and aggressive treatment are crucial, even in severe asthma attacks.
  • A rapid, catastrophic onset of acute asthma, though rare, can be fatal.

Asthma Rescue Drugs

  • Short-acting beta-agonists such as Albuterol, trade names include Proventil, ProAir, Ventolin, are used as rescue medication.
  • Anticholinergics such as Ipratropium, trade name Atrovent, are also used as rescue medication.
  • Combination drugs such as Ipratropium and albuterol, trade name DuoNeb are also used as rescue medication.
  • Systemic corticosteroids such as Prednisone, mainly generic, are also used as rescue medication.

Long-Term Asthma Control

  • Inhaled corticosteroids such as Fluticasone, trade name Flovent, are used for long-term asthma control
  • Long-acting beta-adrenergic agonists such as Salmeterol, trade name Serevent Diskus, are used for long-term asthma control.

Signs and Symptoms of a Potentially Fatal Asthma Attack:

  • Use of accessory muscles during respiration is a sign.
  • Heart rate exceeding 120 beats/min or an increasing heart rate is a sign.
  • Respiratory rate exceeding 25-30 breaths/min is a sign.
  • Difficulty speaking due to dyspnea or fatigue is a sign.
  • Altered level of consciousness is a sign.
  • A quiet chest in a patient with dyspnea or reduced consciousness is a sign.
  • Diaphoresis is a sign.
  • Inability to lie supine due to breathing distress is a sign.
  • Peak expiratory flow is another sign.

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