Podcast
Questions and Answers
What are the three types of neurones involved in ascending spinal tracts?
What are the three types of neurones involved in ascending spinal tracts?
First-order, second-order, and third-order neurones.
Where does the first-order neurone enter the spinal cord?
Where does the first-order neurone enter the spinal cord?
Through the dorsal root of a spinal nerve.
What is the role of the second-order neurone in the sensory pathway?
What is the role of the second-order neurone in the sensory pathway?
It decussates to the opposite side of the CNS and ascends to the thalamus.
Identify the two main tract systems in the spinal cord that follow the three-neurone pattern.
Identify the two main tract systems in the spinal cord that follow the three-neurone pattern.
What sensations are primarily carried by the dorsal columns?
What sensations are primarily carried by the dorsal columns?
Where are the fasciculus gracilis and the fasciculus cuneatus located?
Where are the fasciculus gracilis and the fasciculus cuneatus located?
Which part of the central nervous system does the third-order neurone connect to?
Which part of the central nervous system does the third-order neurone connect to?
Which sensory modality does the first-order neurone transmit to the spinal cord?
Which sensory modality does the first-order neurone transmit to the spinal cord?
What is the role of the fasciculus cuneatus in the nervous system?
What is the role of the fasciculus cuneatus in the nervous system?
Describe the pathway taken by first-order neurones from the fasciculus cuneatus.
Describe the pathway taken by first-order neurones from the fasciculus cuneatus.
What happens to second-order neurones after they receive signals in the medulla?
What happens to second-order neurones after they receive signals in the medulla?
Explain the impact of tabes dorsalis on proprioception.
Explain the impact of tabes dorsalis on proprioception.
How does subacute combined degeneration of the spinal cord manifest?
How does subacute combined degeneration of the spinal cord manifest?
What is the function of the spinothalamic tract?
What is the function of the spinothalamic tract?
What are the consequences of damage to the fasciculus cuneatus in multiple sclerosis?
What are the consequences of damage to the fasciculus cuneatus in multiple sclerosis?
Where do third-order thalamocortical neurones project in the nervous system?
Where do third-order thalamocortical neurones project in the nervous system?
What is referred pain and how does it relate to visceral and somatic pain?
What is referred pain and how does it relate to visceral and somatic pain?
Describe the organization of the spinocerebellar tracts and their role in the nervous system.
Describe the organization of the spinocerebellar tracts and their role in the nervous system.
Identify the two main types of spinocerebellar tracts and their locations in the spinal cord.
Identify the two main types of spinocerebellar tracts and their locations in the spinal cord.
Where do the fibres of the dorsal spinocerebellar tract originate, and how do they ascend?
Where do the fibres of the dorsal spinocerebellar tract originate, and how do they ascend?
What is the primary function of the spinocerebellar system?
What is the primary function of the spinocerebellar system?
Explain the difference between the ascending pathways of the dorsal and ventral spinocerebellar tracts.
Explain the difference between the ascending pathways of the dorsal and ventral spinocerebellar tracts.
What role do mechanoreceptors like Golgi tendon organs play in the spinocerebellar tracts?
What role do mechanoreceptors like Golgi tendon organs play in the spinocerebellar tracts?
Discuss the significance of somatotopic organization in the localization of pain.
Discuss the significance of somatotopic organization in the localization of pain.
Flashcards
Dorsal Columns (aka Posterior Columns)
Dorsal Columns (aka Posterior Columns)
Carries sensory information about touch, pressure, vibration, and proprioception from the body to the brain.
Fasciculus Cuneatus
Fasciculus Cuneatus
The part of the dorsal column responsible for carrying sensory information from the upper body and limbs.
Fasciculus Gracilis
Fasciculus Gracilis
The part of the dorsal column that carries sensory information from the lower body and limbs.
Nucleus Cuneatus
Nucleus Cuneatus
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Nucleus Gracilis
Nucleus Gracilis
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Tabes Dorsalis
Tabes Dorsalis
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Subacute Combined Degeneration of the Spinal Cord
Subacute Combined Degeneration of the Spinal Cord
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Spinothalamic Tract
Spinothalamic Tract
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Ascending Spinal Tracts
Ascending Spinal Tracts
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First-Order Neuron
First-Order Neuron
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Second-Order Neuron
Second-Order Neuron
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Third-Order Neuron
Third-Order Neuron
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Dorsal Columns
Dorsal Columns
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Proprioception
Proprioception
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Referred pain
Referred pain
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Spinocerebellar tracts
Spinocerebellar tracts
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Clarke's column
Clarke's column
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Dorsal spinocerebellar tract
Dorsal spinocerebellar tract
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Ventral spinocerebellar tract
Ventral spinocerebellar tract
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Inferior cerebellar peduncle
Inferior cerebellar peduncle
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Superior cerebellar peduncle
Superior cerebellar peduncle
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Posture and coordination control
Posture and coordination control
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Study Notes
Ascending Spinal Tracts
- Carry sensory information from pain, temperature, tactile, muscle, and joint receptors to the brain.
- Some information goes to conscious areas (cerebral cortex), while some goes to subconscious areas (e.g., cerebellum).
- Pathways to conscious levels have similar characteristics.
- The pathways consist of three neurons:
- First-order neuron: Enters spinal cord via dorsal root, cell body in dorsal root ganglion. Central process branches extensively, forming connections for spinal reflexes and coordination.
- Second-order neuron: Cell body in spinal cord or medulla oblongata. Axon crosses over (decussates) to the opposite side and ascends to the thalamus.
- Third-order neuron: Cell body in the thalamus; axon projects to somatosensory cortex in the parietal lobe of the opposite cerebral hemisphere.
Dorsal Columns
- Located between the dorsal median sulcus and dorsal horn.
- Composed of fasciculus gracilis (medial) and fasciculus cuneatus (lateral).
- Carry information about proprioception (movement/joint position) and discriminative touch.
- Axons of primary afferent neurons enter the cord through dorsal roots.
- Fasciculus gracilis carries information from lower limbs, fasciculus cuneatus from upper limbs.
- Impulses travel to spinal cord without interruption (ipsilateral).
- Synapse in medulla oblongata.
- Axons decussate, forming the medial lemniscus.
- Medial lemniscus terminates in ventral posterior (VP) nucleus of the thalamus.
- Third-order neurons then project to somatosensory cortex.
Spinothalamic Tract
- Also known as the anterolateral system.
- Lies lateral and ventral to the ventral horn of the spinal gray matter.
- Carries information related to pain, temperature, and non-discriminative (crude) touch and pressure.
- Second-order neurons lie in the contralateral dorsal horn.
- Axons cross over (decussate) in the ventral white commissure.
- Ascends in the spinothalamic tract.
- Terminates in the ventral posterior (VP) nucleus of the thalamus.
- Third-order neurons project to the somatosensory cortex.
- Organised somatotopically for high accuracy in locating sensory input.
Spinocerebellar Tracts
- Carry sensory information from muscle spindles, Golgi tendon organs, and tactile receptors to the cerebellum for posture and movement coordination.
- Mostly consist of two neurons:
- First order neurons terminate in the dorsal horn
- Second order neurons ascend to cerebellum, (mostly ipsilateral for dorsal tracts, and contralateral for ventral tracts).
- Includes dorsal and ventral spinocerebellar tracts (lower limbs), and cuneocerebellar and rostral spinocerebellar (upper limbs).
- Terminate in the cerebellar cortex as mossy fibers, mainly in the vermis and paravermal areas.
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