Arthritis and Related Conditions

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Questions and Answers

Which of the following is the most commonly observed symptom in individuals diagnosed with multiple myeloma?

  • Bone pain (correct)
  • Osteomyelitis
  • Fever
  • Pathologic fracture

Which of the following is a characteristic feature of ankylosing spondylitis?

  • Instability of synovial joints
  • Costal cartilage degeneration
  • Temporomandibular joint degeneration
  • Intervertebral joint fusion (correct)

What is a unique characteristic feature of fibromyalgia?

  • Contractures
  • Head pain
  • Muscle atrophy
  • Tender point pain (correct)

The presence of rheumatoid factor autoantibodies in the bloodstream of a patient with rheumatoid arthritis suggests that the condition is likely:

<p>An autoimmune process (B)</p> Signup and view all the answers

A client asks, "Tell me again the name of that chemical that makes crystals when my gout flares up." What is the nurse's most appropriate response?

<p>Uric acid (B)</p> Signup and view all the answers

What preventative measure should a patient diagnosed with systemic lupus erythematosus (SLE) implement to avoid the progression of cutaneous lesions?

<p>Avoid sun exposure (C)</p> Signup and view all the answers

What is the classic presentation of systemic lupus erythematosus (SLE)?

<p>A butterfly pattern rash on the face across the bridge of the nose (D)</p> Signup and view all the answers

In contrast to osteoarthritis, rheumatoid arthritis may be associated with:

<p>Systemic aching in the musculoskeletal system (A)</p> Signup and view all the answers

With which of the following conditions is enteropathic arthritis associated?

<p>Inflammatory bowel disease (D)</p> Signup and view all the answers

What is the underlying cause of joint inflammation in rheumatoid arthritis?

<p>Autoimmune injury (A)</p> Signup and view all the answers

What is the primary process involved in the pathophysiology of rheumatoid arthritis?

<p>Immune cells accumulating in pannus and destroying articular cartilage (B)</p> Signup and view all the answers

What is the earliest manifestation typically seen in scleroderma?

<p>Raynaud phenomenon (B)</p> Signup and view all the answers

What are tophi?

<p>Deposits of urate crystals in tissues (A)</p> Signup and view all the answers

Which of the following best describes the chief pathologic features of osteoarthritis?

<p>Degeneration of articular cartilage, destruction of the bone under the cartilage, and thickening of the synovium (D)</p> Signup and view all the answers

Which disease is similar to osteomalacia but occurs in growing children?

<p>Rickets (D)</p> Signup and view all the answers

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Flashcards

Pathologic fracture

Fracture occurring in diseased bone from minimal trauma.

Fibromyalgia Characteristic

Pain and tenderness in localized areas, muscle stiffness, fatigue, and sleep disturbances.

Rheumatoid Arthritis Cause

An autoimmune process, body attacks its own tissues.

Uric acid

Crystals that accumulate in joints, causing inflammation and pain.

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SLE and Sun Exposure

Avoidance can prevent skin lesion progression.

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SLE Classic Presentation

Butterfly-shaped rash across the face.

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RA Systemic Symptoms

Systemic aching throughout the musculoskeletal system.

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Enteropathic Arthritis Association

Inflammatory bowel disease.

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Rheumatoid Arthritis Cause

Autoimmune injury.

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Rheumatoid Arthritis Pathophysiology

Immune cells accumulating in pannus that destroys articular cartilage.

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Scleroderma Earliest Sign

Thick, tight, shiny skin

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Tophi

Deposits of urate crystals in tissues.

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Osteoarthritis Pathologic Features

Degeneration of articular cartilage, destruction of bone & thickening of synovium.

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Osteomalacia-like Disease in Children

Rickets.

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Brief staring spells in children

Absence seizure

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Study Notes

  • Pathologic fracture is the most common symptom of multiple myeloma.
  • Ankylosing spondylitis causes intervertebral joint fusion.
  • A unique characteristic feature of fibromyalgia is the presence of tender point pain.
  • Rheumatoid arthritis is likely an autoimmune process, indicated by the presence of rheumatoid factor autoantibodies in the bloodstream.
  • Uric acid is the chemical that forms crystals during gout flares.
  • Patients with systemic lupus erythematosus (SLE) should avoid sun exposure to prevent the progression of cutaneous lesions.
  • The classic presentation of systemic lupus erythematosus (SLE) includes a butterfly pattern rash on the face across the bridge of the nose.
  • Rheumatoid arthritis, unlike osteoarthritis, may be associated with systemic aching in the musculoskeletal system.
  • Enteropathic arthritis is associated with inflammatory bowel disease.
  • Rheumatoid arthritis involves joint inflammation caused by autoimmune injury.
  • The pathophysiology of rheumatoid arthritis involves immune cells accumulating in pannus and destroying articular cartilage.
  • The earliest manifestation of scleroderma is Raynaud phenomenon.
  • Tophi are deposits of urate crystals in tissues.
  • The chief pathologic features of osteoarthritis are degeneration of articular cartilage, destruction of the bone under the cartilage, and thickening of the synovium.
  • Rickets, similar to osteomalacia, occurs in growing children.
  • Paget disease is characterized by softening and then enlargement of bones.
  • Subluxation is the displacement of two bones in which the articular surfaces partially lose contact with each other.
  • Osteoarthritis involves activation of cells in bone, cartilage, and the synovial membrane that secrete inflammatory mediators which destroy cartilage and damage bones.
  • Scleroderma involves inflammation and fibrosis of connective tissue.
  • Anticholinesterase inhibitors may be used to manage myasthenia gravis.
  • Absence seizures, characterized by brief staring spells, usually occur in children.
  • Anticonvulsants are helpful in neuropathic pain but not used for acute pain.
  • Blood pressure control is the most important preventive measure for hemorrhagic stroke.
  • Subarachnoid hemorrhage predisposes to cerebral vasospasm, necessitating volume expansion and blood pressure support.
  • Encephalitis is usually caused by a viral infection in brain cells.

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