Arterial Blood Gases (ABGs) analysis

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Questions and Answers

What is the primary purpose of recording a patient's body temperature, position, activity level, and respiratory rate (RR) alongside arterial blood gas (ABG) results?

  • To determine eligibility for supplemental oxygen therapy.
  • To aid in the interpretation of the ABG results by providing context. (correct)
  • To ensure accurate billing for respiratory therapy services.
  • To comply with hospital accreditation standards.

Following a change in a patient's oxygen delivery from 2L nasal cannula to a 6L simple mask, what is the MOST appropriate timeframe to wait before obtaining an ABG sample to assess the patient's response to the change?

  • 1 hour, to allow for complete equilibration of oxygen in the blood.
  • Immediately, to ensure the patient is tolerating the increased oxygen.
  • 15 minutes, to allow for initial stabilization. (correct)
  • 30 minutes, to allow for stabilization of blood gases.

Which of the following arterial blood gas (ABG) values directly reflects the effectiveness of gas exchange between the lungs and the blood?

  • PaO2 (Partial Pressure of Oxygen in Arterial Blood) (correct)
  • SaO2 (Arterial Oxygen Saturation)
  • HCO3- (Bicarbonate Concentration)
  • CaO2 (Arterial Oxygen Content)

Which of the following best describes the clinical significance of CaO2 (Arterial Oxygen Content) in assessing a patient's oxygenation status?

<p>It reflects the overall amount of oxygen in arterial blood, considering both hemoglobin saturation and concentration. (C)</p> Signup and view all the answers

In assessing a patient's acid-base status using arterial blood gas (ABG) analysis, which set of parameters are DIRECTLY measured by the blood gas analyzer?

<p>pH, PaCO2, and PaO2 (A)</p> Signup and view all the answers

Which clinical scenario would warrant an arterial blood gas (ABG) analysis?

<p>Assessment of a patient experiencing a sudden onset of dyspnea and cyanosis. (A)</p> Signup and view all the answers

Following a significant adjustment to ventilator settings for a patient in the ICU, what is the MOST appropriate next step?

<p>Wait 15 minutes and then draw an ABG to assess the patient's response to the changes. (C)</p> Signup and view all the answers

If a laboratory requires actual measurement of total hemoglobin saturation, methemoglobin, or carboxyhemoglobin levels, which of the following methods should be utilized?

<p>Co-oximetry (D)</p> Signup and view all the answers

What is a key advantage of using a polargraphic electrode (Clark electrode) in oxygen analysis compared to a galvanic fuel cell?

<p>It offers a faster response time due to the presence of a battery. (D)</p> Signup and view all the answers

What key factor differentiates a galvanic fuel cell oxygen analyzer from a Clark polarographic electrode?

<p>Galvanic fuel cells do not require batteries and generate their own current. (B)</p> Signup and view all the answers

Which environmental factor does NOT typically affect the accuracy and calibration of both polarographic and galvanic fuel cell oxygen analyzers?

<p>Stable Ambient Lighting (C)</p> Signup and view all the answers

What is the primary function of co-oximetry in blood gas analysis?

<p>To differentiate and quantify various forms of hemoglobin, such as oxyhemoglobin, methemoglobin, and carboxyhemoglobin. (C)</p> Signup and view all the answers

Which electrode is used to measure PCO2 in blood gas analysis?

<p>Servinghaus electrode (B)</p> Signup and view all the answers

In blood gas analysis, which electrode is utilized to directly measure pH?

<p>Sanz electrode (B)</p> Signup and view all the answers

What is the purpose of plotting control media analyses on a graph with statistically derived limits (+/- 2 standard deviations) in blood gas quality control?

<p>To identify and minimize analytic errors, ensuring the reliability of blood gas results. (A)</p> Signup and view all the answers

What does it indicate when the results of control media analyses fall outside the established statistical limits (typically ± 2 standard deviations) in blood gas quality control?

<p>There is a potential analytical error affecting the accuracy of the blood gas results. (B)</p> Signup and view all the answers

What is the primary advantage of point-of-care testing (POCT) for blood gas analysis?

<p>Faster diagnosis and treatment due to rapid availability of results. (A)</p> Signup and view all the answers

What is the typical timeframe within which point-of-care blood gas testing must be performed after sample collection to ensure accuracy?

<p>Within 1-2 minutes. (B)</p> Signup and view all the answers

What is the underlying principle behind transcutaneous blood gas monitoring?

<p>Noninvasive estimation of arterial PO2 and PCO2 through a surface skin sensor, enhanced by heating the skin. (A)</p> Signup and view all the answers

In what patient population is transcutaneous blood gas monitoring MOST commonly used?

<p>Neonates and infants (C)</p> Signup and view all the answers

What physiological principle does pulse oximetry rely on to measure blood hemoglobin saturation?

<p>Spectrophotometry (D)</p> Signup and view all the answers

What two technologies are combined in pulse oximetry (POX) to achieve noninvasive measurement of blood Hb saturations?

<p>Spectrophotometry and photoplethysmography (C)</p> Signup and view all the answers

What wavelengths of light are commonly used in pulse oximetry to differentiate between oxygenated and deoxygenated hemoglobin?

<p>Red and infrared light (D)</p> Signup and view all the answers

Under what SpO2 conditions does pulse oximetry become unreliable?

<p>SpO2 &lt; 90% (D)</p> Signup and view all the answers

When performing the Modified Allen Test prior to arterial puncture, which of the following observations would indicate adequate collateral circulation, suggesting it is safe to proceed with the puncture?

<p>The hand flushes within 5-10 seconds after releasing pressure on the ulnar artery. (D)</p> Signup and view all the answers

A patient presents with sudden, unexplained dyspnea accompanied by the heavy use of accessory muscles. Based solely on these observations, what immediate intervention should be prioritized before obtaining an ABG sample?

<p>Providing supplemental oxygen and assessing the patient's response. (A)</p> Signup and view all the answers

A patient on a mechanical ventilator exhibits acute hypotension and a sudden deterioration in neurologic function. After ensuring adequate ventilation and perfusion, what blood gas abnormality would MOST strongly suggest the need for immediate changes in ventilator settings?

<p>A rapidly rising PaCO2 above the patient's baseline, indicating acute respiratory acidosis. (A)</p> Signup and view all the answers

During cardiopulmonary resuscitation (CPR), what is the MOST critical reason for obtaining an arterial blood gas (ABG) sample?

<p>To evaluate the effectiveness of chest compressions and ventilation, guiding adjustments to improve oxygenation and acid-base balance. (D)</p> Signup and view all the answers

In the context of blood gas quality control, what is the distinction between random error and systemic error, and how does each affect the interpretation of blood gas results?

<p>Random error is unpredictable and affects individual measurements, while systemic error is consistent and affects all measurements in a similar way. (C)</p> Signup and view all the answers

A blood gas analyzer displays a PaO2 value that is significantly higher than expected for a patient receiving a known FiO2. Assuming the analyzer is functioning correctly, what pre-analytical error could explain this discrepancy?

<p>An air bubble was introduced into the sample, falsely elevating the PaO2 reading. (B)</p> Signup and view all the answers

A respiratory therapist is using a point-of-care blood gas analyzer in a busy emergency department. After running a control sample, the results fall slightly outside the acceptable range for one parameter (e.g., pH). What is the MOST appropriate course of action?

<p>Repeat the control sample analysis immediately to confirm the error. (D)</p> Signup and view all the answers

In transcutaneous blood gas monitoring, why is it essential to change the sensor site periodically?

<p>To prevent thermal injury and maintain skin integrity. (B)</p> Signup and view all the answers

A pulse oximeter consistently reads significantly lower than expected on a patient, despite a strong pulsatile signal. What factor should be investigated FIRST?

<p>Potential sources of artifact, such as excessive patient movement or external light interference. (A)</p> Signup and view all the answers

A patient with carbon monoxide poisoning is being monitored with pulse oximetry. Why might the SpO2 reading be misleading?

<p>Carboxyhemoglobin absorbs light at the same wavelengths as oxyhemoglobin, leading to a falsely elevated SpO2 reading. (D)</p> Signup and view all the answers

Which statement best describes the relationship between PaO2 and SpO2 and their clinical significance?

<p>PaO2 reflects dissolved oxygen in the blood, while SpO2 indicates the percentage of hemoglobin saturated with oxygen; they provide complementary information about a patient's oxygenation status. (D)</p> Signup and view all the answers

Which of the following scenarios would contraindicate performing an arterial puncture at a specific site, regardless of a normal Modified Allen Test result?

<p>The presence of a dialysis fistula proximal to the intended puncture site. (C)</p> Signup and view all the answers

A patient undergoing mechanical ventilation develops a sudden, sharp decrease in end-tidal CO2 (ETCO2) accompanied by a drop in blood pressure. What immediate action should the respiratory therapist take, assuming proper ventilator function?

<p>Immediately assess the patient for potential pulmonary embolism or other causes of decreased pulmonary perfusion. (B)</p> Signup and view all the answers

A patient's ABG results reveal a normal pH and PaCO2, but the PaO2 is critically low despite a high FiO2. What condition should be suspected?

<p>V/Q mismatch (D)</p> Signup and view all the answers

Following initiation of mechanical ventilation, a patient's PaCO2 remains elevated despite adjustments to the respiratory rate and tidal volume. Which additional blood gas parameter should be evaluated in conjunction with ventilator settings to optimize CO2 removal?

<p>pH (A)</p> Signup and view all the answers

During blood gas analysis, a respiratory therapist observes that a control solution's pH value is consistently above the acceptable range (outside +2 standard deviations) over several days. Assuming proper handling and storage of the control solution, what is the MOST likely cause of this systematic error?

<p>Deterioration of the Sanz electrode used for pH measurement. (A)</p> Signup and view all the answers

A premature infant in the NICU is being monitored via transcutaneous blood gas monitoring. Over a 4-hour period, the transcutaneous PCO2 (PtcCO2) values gradually increase while the transcutaneous PO2 (PtcO2) values decrease, despite stable ventilator settings and FiO2. What is the MOST likely explanation for this trend?

<p>Worsening pulmonary function and increased CO2 production. (A)</p> Signup and view all the answers

A patient with severe anemia (Hb = 6 g/dL) is being monitored with pulse oximetry. While the SpO2 reading is 95%, the respiratory therapist suspects that this value may not accurately reflect the patient's oxygenation status. Which additional parameter should be assessed in conjunction with pulse oximetry to provide a more comprehensive evaluation of the patient's oxygen-carrying capacity?

<p>Arterial oxygen content (CaO2) (D)</p> Signup and view all the answers

During an arterial puncture, the respiratory therapist observes a sudden gush of pulsatile blood that is bright red, but the patient immediately complains of intense pain, and resistance is felt during further needle advancement. What is the MOST appropriate immediate action?

<p>Withdraw the needle immediately and apply firm pressure, suspecting possible arterial spasm or nerve irritation. (D)</p> Signup and view all the answers

Flashcards

What to record for ABGs?

Date, time, site of ABG draw, results of Modified Allen Test, patient's body temperature, position, activity level, respiratory rate, FiO2 and ventilator settings.

ABG Timing After O2 Change

Wait approximately 15 minutes after changing a patient's oxygen delivery device or settings before obtaining an ABG sample.

PaO2

Represents the partial pressure of O2 dissolved in the plasma and reflects gas exchange in the lungs.

SaO2

Represents the degree to which hemoglobin is saturated with oxygen.

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CaO2

Represents the total content of oxygen in arterial blood, considering both dissolved oxygen and oxygen bound to hemoglobin.

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Key Acid-Base Indicators

pH, PaCO2, and HCO3 are the primary parameters used to determine acid-base status.

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ABG Clinical Indications

Sudden dyspnea, cyanosis, abnormal breath sounds, tachypnea, accessory muscle use, changes in vent settings, CPR, hypotension and neurological deterioration.

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Measuring Hb saturation

Electrochemical O2 Analyzers or CO-oximetry

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Clark polarographic electrode

Measures oxygen partial pressure.

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Galvanic fuel cell

No batteries, and makes its own current

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Factors Affecting O2 Analyzers

Temperature, pressure, and humidity.

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pH Measurement

Uses the Sanz electrode.

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CO2 Measurement

Uses the Severinghaus electrode.

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Quality Control

Plots control media analyses on a graph compared with statistically derived limits (+/- 2 SD).

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Control Results Outside Limits

Indicates analytic error.

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Point of Care Testing

Takes blood gas analysis from the lab to the patient’s bedside, allowing quicker diagnosis and treatment.

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POCT tests

Chemistry, hematology, LA, PT/PTT, troponin

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Transcutaneous Monitoring

Provides continuous noninvasive estimates of arterial PO2 and PCO2 through a skin surface sensor.

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Pulse Oximetry

Measurement of blood Hb saturations using spectrophotometry. Combines spectrophotometry and photoplethysmography.

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Study Notes

  • Arterial Blood Gases (ABGs) require recording the date, time, site of the sample, results of the Modified Allen Test, patient's body temperature, position, activity level, respiratory rate, FiO2, and ventilator settings to aid in result interpretation.
  • Following a change in oxygen delivery, such as switching a patient from a 2L nasal cannula to a 6L simple mask, wait 15 minutes before obtaining an ABG.

Determining Oxygenation Status

  • PaO2 represents the partial pressure of oxygen dissolved in the plasma of arterial blood, reflecting gas exchange between the lungs and blood, and it is used to determine the level of hypoxemia (mild, moderate, or severe).
  • SaO2 indicates the degree to which hemoglobin is saturated with oxygen.
  • CaO2 represents the content of oxygen in arterial blood, dependent on the amount of hemoglobin present and its saturation.

Determining Acid-Base Status

  • Acid-base status is determined by pH, PaCO2, and HCO3 levels.

Clinical Indications for ABGs

  • Indications include sudden, unexplained dyspnea, cyanosis, abnormal breath sounds, severe tachypnea, heavy use of accessory muscles, changes in ventilator settings, cardiopulmonary resuscitation (CPR), acute hypotension, and acute deterioration in neurologic function.

Analyzing ABGs

  • Blood gas analyzers measure pH, PCO2, and PO2 directly.
  • Bicarbonate (HCO3) and Base Excess/Deficit (BE/BD) are calculated from measured values.
  • Co-oximetry is required for the measurement of total Hemoglobin saturation, Methemoglobin, or Carboxyhemoglobin.

Oxygen Analyzers

  • Electrochemical O2 analyzers includes the Polargraphic (Clark) electrode and the Galvanic fuel cell.
  • The Clark electrode uses a battery for a faster response, relying on an O2 mediated chemical reaction to produce a current.
  • The Galvanic fuel cell does not require batteries, generating its own current.
  • Both analyzers are affected by temperature, pressure, humidity, and altitude and require recalibration. Temperature and pressure increases the reading, humidity and altitude decreases it.

ABG Machine Electrodes

  • The Clark polarographic electrode is used to measure PO2 in blood gas analyzers.
  • The Sanz electrode is used to measure pH.
  • The Severinghaus electrode is used to measure CO2.

Quality Control (QC)

  • QC involves plotting control media analyses results on a graph and comparing them with statistically derived limits, typically ±2 standard deviations (SD).
  • Results falling outside this range indicate analytic error (random or systemic errors).

Point of Care Testing

  • Point of care testing moves blood gas analysis from the specialized lab to the patient’s bedside.
  • It leads to quicker diagnosis and treatment.
  • Point of care testing includes chemistry, hematology, lactate, Prothrombin Time (PT), Partial Thromboplastin Time (PTT), and troponin.
  • Samples must be run within 1-2 minutes using a disposable cartridge.

Transcutaneous Blood Gas Monitoring

  • This method provides continuous, noninvasive estimates of arterial PO2 and PCO2 through a skin surface sensor.
  • The sensor heats the skin, similar to capillary blood gas sampling.
  • It is primarily used with babies.

Pulse Oximetry

  • Pulse oximetry measures blood hemoglobin saturations using spectrophotometry.
  • Pulse oximetry combines spectrophotometry and photoplethysmography.
  • It uses one red light (660 nm) and one infrared light (940 nm).
  • Pulse oximetry is unreliable at SpO2 levels < 80%.

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