Arrhythmia Treatment Techniques and Drugs
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Questions and Answers

What is one reason why non-pharmacological techniques are preferred for arrhythmia treatment?

  • They completely eliminate the need for medications.
  • They require no special equipment.
  • They have fewer side effects compared to medications. (correct)
  • They are faster in treating immediate symptoms.

Which of the following is NOT a non-pharmacological technique for treating arrhythmias?

  • Quinidine administration (correct)
  • Artificial pacemaker
  • Implantable cardioverter defibrillator
  • Ablation technique

Which class of antiarrhythmic drug predominantly blocks sodium channels and increases action potential duration (APD)?

  • Class Ic
  • Class II
  • Class Ib
  • Class Ia (correct)

What is a common characteristic of Class Ib antiarrhythmic drugs?

<p>They have no effect on potassium channels or APD. (A)</p> Signup and view all the answers

Which of the following antiarrhythmic drugs is indicated for oral use and commonly used?

<p>Mexiletine (C)</p> Signup and view all the answers

What are potential adverse effects of the drug mentioned in the therapeutic uses for atrial arrhythmia?

<p>Cinchonism (D)</p> Signup and view all the answers

Which of the following is a therapeutic use for the described drug?

<p>Atrial flutter (A)</p> Signup and view all the answers

What is the recommended route of administration for the therapeutic effects mentioned for arrhythmias?

<p>Oral or IV (B)</p> Signup and view all the answers

Which condition is particularly noted for being induced by digitalis?

<p>Arrhythmias (C)</p> Signup and view all the answers

What aspect of metabolism is highlighted for the therapy provided?

<p>Acetylation in the liver (C)</p> Signup and view all the answers

Study Notes

Non-Pharmacological Techniques for Arrhythmia Treatment

  • Non-pharmacological techniques are preferred for arrhythmia treatment due to the arrhythmogenic effects of some drugs and the efficacy of these techniques.
  • Non-pharmacological techniques include Ablation, Implantable Cardioverter Defibrillator, Artificial Pacemaker, Vagal Stimulation, and DC Shock.

Class I Antiarrhythmic Drugs

  • Class I antiarrhythmic drugs block sodium channels, affecting the rate of depolarization and the duration of the action potential.
  • Ia drugs block sodium and potassium channels, increasing the duration of the action potential.
    • Examples: Quinidine, Procainamide, Disopyramide.
  • Ib drugs block sodium channels but have little to no effect on potassium channels or the duration of the action potential.
    • Examples: Lidocaine, Mexiletine, Phenytoin.
  • Ic drugs block sodium channels and have no effect on potassium channels or the duration of the action potential.
    • Examples: Flecainide, Propafenone.

Class II (β-blockers)

  • Beta-blockers decrease heart rate, contractility, and conduction velocity.
  • Examples: Esmolol, Propranolol, Sotalol.

Class III (K channel blockers)

  • Class III drugs block potassium channels, prolonging the action potential duration.
  • Examples: Amiodarone, Dofetilide, Sotalol.

Class IV (Ca channel blockers)

  • Class IV drugs block calcium channels, reducing heart rate and contractility.
  • Examples: Verapamil, Dronedarone.

Other Antiarrhythmic Drugs

  • Adenosine is used for emergency treatments of supraventricular tachycardias.
  • Digoxin is used for prophylaxis of supraventricular tachycardia, but not for emergency treatment.
  • Magnesium Sulfate is used for Torsades de Pointes.

Emergency and Prophylaxis Treatment

  • Emergency treatment for supraventricular arrhythmia includes adenosine.
  • Prophylaxis treatment for supraventricular arrhythmia includes digitalis, beta blockers, Ca channel blockers, and amiodarone.
  • Emergency treatment for ventricular arrhythmia includes Class Ib agents, such as lidocaine, and DC shock.
  • Prophylaxis treatment for ventricular arrhythmia includes mexiletine and phenytoin.
  • Torsades de Pointes is treated with Magnesium Sulfate.

Wolf-Parkinson-White Syndrome

  • Amiodarone and Sotalol are used to treat Wolf-Parkinson-White Syndrome.
  • Class Ib drugs can also be used to treat Wolf-Parkinson-White Syndrome.

N.B.

  • Bradyarrhythmia is treated with atropine or corticosteroids.

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Description

Explore non-pharmacological techniques for treating arrhythmia and understand the various Class I antiarrhythmic drugs. This quiz covers methods such as Ablation and Implantable Cardioverter Defibrillator, alongside the pharmacological mechanisms of Class I drugs. Test your knowledge on important treatments and medications for arrhythmia.

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