Are You Immunodeficient? 19.4
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Questions and Answers

Which type of immunodeficiency is caused by inherited defects of either nonspecific innate or specific adaptive immune defenses?

  • Primary immunodeficiencies (correct)
  • Neither primary nor secondary immunodeficiencies
  • Secondary immunodeficiencies
  • Both primary and secondary immunodeficiencies

    • What is the most common cause of immunodeficiencies globally?

  • Prolonged critical illness
  • Systemic disorders
  • Immunosuppressive treatments
  • Severe malnutrition (correct)

    • What is the characteristic feature of X-linked agammaglobulinemia?

  • Absence of immunoglobulin in the serum (correct)
  • Impaired T-cell dependent antibody responses
  • Defects in the NADPH oxidase system of phagocytic cells
  • Selective IgA deficiency

    • What is the cause of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the prevalence of selective IgA deficiency?

    <p>1 in 800</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiency worldwide?

    <p>Severe malnutrition</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Impairs T-cell dependent antibody responses and cell-mediated immune responses</p> Signup and view all the answers

    What is the difference between primary and secondary immunodeficiencies?

    <p>Primary immunodeficiencies are caused by inherited defects of either nonspecific innate or specific adaptive immune defenses, while secondary immunodeficiencies occur as a result of acquired impairment of function of B cells, T cells, or both</p> Signup and view all the answers

    What is the cause of secondary immunodeficiencies?

    <p>Prolonged critical illness</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the feature of selective IgA deficiency?

    <p>Predisposition to lung and gastrointestinal infections</p> Signup and view all the answers

    Which type of immunodeficiency is caused by inherited defects of either nonspecific innate or specific adaptive immune defenses?

    <p>Primary immunodeficiencies</p> Signup and view all the answers

    What is the most common cause of immunodeficiencies globally?

    <p>Severe malnutrition</p> Signup and view all the answers

    What is the characteristic feature of X-linked agammaglobulinemia?

    <p>Absence of immunoglobulin in the serum</p> Signup and view all the answers

    What is the cause of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the prevalence of selective IgA deficiency?

    <p>1 in 800</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiency worldwide?

    <p>Severe malnutrition</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Impairs T-cell dependent antibody responses and cell-mediated immune responses</p> Signup and view all the answers

    What is the difference between primary and secondary immunodeficiencies?

    <p>Primary immunodeficiencies are caused by inherited defects of either nonspecific innate or specific adaptive immune defenses, while secondary immunodeficiencies occur as a result of acquired impairment of function of B cells, T cells, or both</p> Signup and view all the answers

    What is the cause of secondary immunodeficiencies?

    <p>Prolonged critical illness</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the feature of selective IgA deficiency?

    <p>Predisposition to lung and gastrointestinal infections</p> Signup and view all the answers

    Which type of immunodeficiency is caused by inherited defects?

    <p>Primary immunodeficiency</p> Signup and view all the answers

    What is the most common cause of immunodeficiencies globally?

    <p>Malnutrition</p> Signup and view all the answers

    Which of the following is an example of primary immunodeficiency?

    <p>Chronic granulomatous disease</p> Signup and view all the answers

    What is the characteristic feature of X-linked agammaglobulinemia?

    <p>Absence of immunoglobulin in the serum</p> Signup and view all the answers

    Which immunodeficiency affects about one in 800 people?

    <p>Selective IgA deficiency</p> Signup and view all the answers

    What is the main feature of severe combined immunodeficiency (SCID)?

    <p>Impaired T-cell function</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiency worldwide?

    <p>Malnutrition</p> Signup and view all the answers

    Which type of immunodeficiency is often reversible if the underlying cause is resolved?

    <p>Secondary immunodeficiency</p> Signup and view all the answers

    What causes chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    Which type of immunodeficiency is caused by acquired impairment of function?

    <p>Secondary immunodeficiency</p> Signup and view all the answers

    What is the main consequence of primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the main consequence of severe combined immunodeficiency (SCID)?

    <p>Impaired T-cell function</p> Signup and view all the answers

    Which type of immunodeficiency affects about one in 800 people, predisposing them to lung and gastrointestinal infections?

    <p>X-linked agammaglobulinemia</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Patients cannot develop immunological memory</p> Signup and view all the answers

    What is the difference between primary and secondary immunodeficiencies?

    <p>Primary immunodeficiencies are caused by inherited defects of either nonspecific innate or specific adaptive immune defenses, while secondary immunodeficiencies occur as a result of acquired impairment of function of B cells, T cells, or both</p> Signup and view all the answers

    What is the cause of secondary immunodeficiencies?

    <p>Acquired impairment of function of B cells, T cells, or both</p> Signup and view all the answers

    What is the prevalence of selective IgA deficiency?

    <p>About one in 800 people</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiency worldwide?

    <p>Malnutrition</p> Signup and view all the answers

    What is the characteristic feature of X-linked agammaglobulinemia?

    <p>Absence of immunoglobulin in the serum</p> Signup and view all the answers

    What is the feature of patients with chronic granulomatous disease (CGD)?

    <p>Chronic local inflammation called a granuloma</p> Signup and view all the answers

    Which type of immunodeficiency is caused by inherited defects of either nonspecific innate or specific adaptive immune defenses?

    <p>Primary immunodeficiency</p> Signup and view all the answers

    What is the feature of patients with severe combined immunodeficiency (SCID)?

    <p>Patients cannot develop immunological memory</p> Signup and view all the answers

    What is the most common cause of immunodeficiencies in developed countries?

    <p>Inherited defects</p> Signup and view all the answers

    Which type of immunodeficiency affects about one in 800 people and predisposes them to lung and gastrointestinal infections?

    <p>Selective IgA deficiency</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    Which type of immunodeficiency impairs T-cell dependent antibody responses and cell-mediated immune responses and patients cannot develop immunological memory?

    <p>Severe combined immunodeficiency</p> Signup and view all the answers

    What is the difference between primary and secondary immunodeficiencies?

    <p>Primary immunodeficiencies are caused by inherited defects, while secondary immunodeficiencies are acquired</p> Signup and view all the answers

    What is the feature of X-linked agammaglobulinemia?

    <p>Absence of immunoglobulin in the serum</p> Signup and view all the answers

    What is the prevalence of selective IgA deficiency?

    <p>1 in 800</p> Signup and view all the answers

    Which type of immunodeficiency is caused by defects in the NADPH oxidase system of phagocytic cells, leading to chronic local inflammation called a granuloma?

    <p>Chronic granulomatous disease</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Impaired T-cell dependent antibody responses and cell-mediated immune responses</p> Signup and view all the answers

    What is the cause of secondary immunodeficiencies?

    <p>Acquired impairment of function of B cells, T cells, or both</p> Signup and view all the answers

    Which type of immunodeficiency affects about one in 800 people and predisposes them to lung and gastrointestinal infections?

    <p>Selective IgA deficiency</p> Signup and view all the answers

    Which type of immunodeficiency affects about one in 800 people, predisposing them to lung and gastrointestinal infections?

    <p>Primary immunodeficiency</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>They have an increased susceptibility to infection</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Impaired T-cell dependent antibody responses</p> Signup and view all the answers

    What is the most common cause of primary immunodeficiencies in developed countries?

    <p>Inherited defects</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiencies in developed countries?

    <p>Systemic disorders</p> Signup and view all the answers

    Which immunodeficiency is characterized by the absence of immunoglobulin in the serum, leading to recurrent infections almost exclusively due to extracellular pathogens?

    <p>X-linked agammaglobulinemia</p> Signup and view all the answers

    What is the difference between primary and secondary immunodeficiencies?

    <p>Primary immunodeficiencies are caused by inherited defects, while secondary immunodeficiencies are acquired</p> Signup and view all the answers

    What is the cause of chronic local inflammation called a granuloma in chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    Which immunodeficiency affects about one in 800 people?

    <p>Selective IgA deficiency</p> Signup and view all the answers

    Which type of immunodeficiency is often reversible if the underlying cause is resolved?

    <p>Secondary immunodeficiency</p> Signup and view all the answers

    What is the feature of patients with severe combined immunodeficiency (SCID)?

    <p>They have an increased susceptibility to infection</p> Signup and view all the answers

    What is the most common cause of immunodeficiencies in developed countries?

    <p>Inherited defects</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the prevalence of selective IgA deficiency?

    <p>1 in 800 people</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Cannot develop immunological memory</p> Signup and view all the answers

    What is the cause of secondary immunodeficiencies?

    <p>Prolonged critical illness</p> Signup and view all the answers

    What is the characteristic feature of X-linked agammaglobulinemia?

    <p>Absence of immunoglobulin in the serum</p> Signup and view all the answers

    What is the difference between primary and secondary immunodeficiencies?

    <p>Primary immunodeficiencies are caused by inherited defects, while secondary immunodeficiencies are acquired</p> Signup and view all the answers

    What is the feature of patients with chronic granulomatous disease (CGD)?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the feature of patients with selective IgA deficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiency worldwide?

    <p>Severe malnutrition</p> Signup and view all the answers

    What is the feature of patients with severe combined immunodeficiency (SCID)?

    <p>Cannot develop immunological memory</p> Signup and view all the answers

    What is the cause of primary immunodeficiencies?

    <p>Inherited defects of either nonspecific innate or specific adaptive immune defenses</p> Signup and view all the answers

    Which type of immunodeficiency is characterized by the absence of immunoglobulin in the serum?

    <p>X-linked agammaglobulinemia</p> Signup and view all the answers

    What is the prevalence of selective IgA deficiency?

    <p>1 in 800 people</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Impairs T-cell dependent antibody responses and cell-mediated immune responses</p> Signup and view all the answers

    What is the cause of secondary immunodeficiencies?

    <p>Acquired impairment of function of B cells, T cells, or both</p> Signup and view all the answers

    Which immunodeficiency is caused by defects in the NADPH oxidase system of phagocytic cells?

    <p>Chronic granulomatous disease</p> Signup and view all the answers

    What is the most common cause of immunodeficiencies in developed countries?

    <p>Inherited defects</p> Signup and view all the answers

    Which type of immunodeficiency affects both innate and adaptive immunity?

    <p>Secondary immunodeficiencies</p> Signup and view all the answers

    What is the characteristic feature of selective IgA deficiency?

    <p>Increased susceptibility to extracellular pathogens</p> Signup and view all the answers

    Which type of immunodeficiency impairs the function of T cells only?

    <p>Severe combined immunodeficiency</p> Signup and view all the answers

    Which type of immunodeficiency is often reversible if the underlying cause is resolved?

    <p>Secondary immunodeficiencies</p> Signup and view all the answers

    Which type of immunodeficiency affects about one in 800 people, predisposing them to lung and gastrointestinal infections?

    <p>Selective IgA deficiency</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Inability to develop immunological memory</p> Signup and view all the answers

    What is the most common cause of immunodeficiencies in developed countries?

    <p>Inherited defects</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiencies in developed countries?

    <p>Immunosuppressive treatments</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiencies in developing countries?

    <p>Malnutrition</p> Signup and view all the answers

    What is the characteristic feature of X-linked agammaglobulinemia?

    <p>Absence of immunoglobulin in the serum</p> Signup and view all the answers

    What is the characteristic feature of selective IgA deficiency?

    <p>Impaired T-cell dependent antibody responses</p> Signup and view all the answers

    What type of immunodeficiency can be caused by systemic disorders?

    <p>Secondary immunodeficiency</p> Signup and view all the answers

    What type of immunodeficiency is caused by inherited defects of either nonspecific innate or specific adaptive immune defenses?

    <p>Primary immunodeficiency</p> Signup and view all the answers

    What is the feature of patients with chronic granulomatous disease (CGD)?

    <p>Chronic local inflammation called a granuloma</p> Signup and view all the answers

    What is the primary cause of immunodeficiencies globally?

    <p>Severe malnutrition</p> Signup and view all the answers

    Which type of immunodeficiency affects about one in 800 people?

    <p>Selective IgA deficiency</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    What is the feature of patients born with primary immunodeficiency?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    What is the characteristic feature of X-linked agammaglobulinemia?

    <p>Absence of immunoglobulin in the serum</p> Signup and view all the answers

    What is the feature of selective IgA deficiency?

    <p>Predisposition to lung and gastrointestinal infections</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Impaired T-cell dependent antibody responses and cell-mediated immune responses</p> Signup and view all the answers

    What is the cause of secondary immunodeficiencies?

    <p>Systemic disorders</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiency worldwide?

    <p>Severe malnutrition</p> Signup and view all the answers

    What is the difference between primary and secondary immunodeficiencies?

    <p>Primary immunodeficiencies are inherited, while secondary immunodeficiencies are acquired</p> Signup and view all the answers

    Which type of immunodeficiency leads to recurrent infections almost exclusively due to extracellular pathogens?

    <p>X-linked agammaglobulinemia</p> Signup and view all the answers

    Which type of immunodeficiency impairs T-cell dependent antibody responses and cell-mediated immune responses?

    <p>Severe combined immunodeficiency</p> Signup and view all the answers

    What is the most common cause of immunodeficiencies in developed countries?

    <p>Inherited defects</p> Signup and view all the answers

    What is the main consequence of primary immunodeficiencies?

    <p>Increased susceptibility to infection</p> Signup and view all the answers

    Which of the following is an example of primary immunodeficiency?

    <p>Severe combined immunodeficiency disease</p> Signup and view all the answers

    What is the cause of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    Which of the following is a characteristic feature of X-linked agammaglobulinemia?

    <p>Absence of immunoglobulin in the serum</p> Signup and view all the answers

    What is the prevalence of selective IgA deficiency?

    <p>About one in 800 people</p> Signup and view all the answers

    What is the feature of severe combined immunodeficiency (SCID)?

    <p>Impairs T-cell dependent antibody responses and cell-mediated immune responses</p> Signup and view all the answers

    What is the main cause of secondary immunodeficiencies worldwide?

    <p>Severe malnutrition</p> Signup and view all the answers

    What is the feature of patients with secondary immunodeficiencies?

    <p>Impaired function of B cells, T cells, or both</p> Signup and view all the answers

    Are secondary immunodeficiencies reversible?

    <p>Yes, if the underlying cause is resolved</p> Signup and view all the answers

    Which of the following is NOT an example of primary immunodeficiency?

    <p>HIV/AIDS</p> Signup and view all the answers

    What is the most common cause of immunodeficiencies globally?

    <p>Malnutrition</p> Signup and view all the answers

    What is the primary cause of immunodeficiencies globally?

    <p>Malnutrition</p> Signup and view all the answers

    What is the characteristic feature of chronic granulomatous disease (CGD)?

    <p>Defects in the NADPH oxidase system of phagocytic cells</p> Signup and view all the answers

    Which immunodeficiency impairs T-cell dependent antibody responses and cell-mediated immune responses?

    <p>Severe combined immunodeficiency</p> Signup and view all the answers

    What is the prevalence of selective IgA deficiency?

    <p>1 in 800 people</p> Signup and view all the answers

    Which type of immunodeficiency is caused by acquired impairment of function of B cells, T cells, or both?

    <p>Secondary immunodeficiency</p> Signup and view all the answers

    What is the most common cause of secondary immunodeficiency worldwide?

    <p>Malnutrition</p> Signup and view all the answers

    Which immunodeficiency is characterized by the absence of immunoglobulin in the serum?

    <p>X-linked agammaglobulinemia</p> Signup and view all the answers

    Which immunodeficiency predisposes individuals to lung and gastrointestinal infections?

    <p>Selective IgA deficiency</p> Signup and view all the answers

    Which immunodeficiency leads to chronic local inflammation called a granuloma?

    <p>Chronic granulomatous disease</p> Signup and view all the answers

    Which immunodeficiency impairs the ability to develop immunological memory?

    <p>Severe combined immunodeficiency</p> Signup and view all the answers

    Which type of immunodeficiency is often reversible if the underlying cause is resolved?

    <p>Secondary immunodeficiency</p> Signup and view all the answers

    What is the primary cause of immunodeficiencies in developed countries?

    <p>Inherited defects</p> Signup and view all the answers

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