Are You Immunodeficient? 19.4

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Questions and Answers

Which type of immunodeficiency is caused by inherited defects of either nonspecific innate or specific adaptive immune defenses?

  • Primary immunodeficiencies (correct)
  • Neither primary nor secondary immunodeficiencies
  • Secondary immunodeficiencies
  • Both primary and secondary immunodeficiencies

What is the most common cause of immunodeficiencies globally?

  • Prolonged critical illness
  • Systemic disorders
  • Immunosuppressive treatments
  • Severe malnutrition (correct)

What is the characteristic feature of X-linked agammaglobulinemia?

  • Absence of immunoglobulin in the serum (correct)
  • Impaired T-cell dependent antibody responses
  • Defects in the NADPH oxidase system of phagocytic cells
  • Selective IgA deficiency

What is the cause of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (B)</p> Signup and view all the answers

What is the prevalence of selective IgA deficiency?

<p>1 in 800 (D)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiency worldwide?

<p>Severe malnutrition (B)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>Increased susceptibility to infection (B)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Impairs T-cell dependent antibody responses and cell-mediated immune responses (B)</p> Signup and view all the answers

What is the difference between primary and secondary immunodeficiencies?

<p>Primary immunodeficiencies are caused by inherited defects of either nonspecific innate or specific adaptive immune defenses, while secondary immunodeficiencies occur as a result of acquired impairment of function of B cells, T cells, or both (B)</p> Signup and view all the answers

What is the cause of secondary immunodeficiencies?

<p>Prolonged critical illness (C)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (B)</p> Signup and view all the answers

What is the feature of selective IgA deficiency?

<p>Predisposition to lung and gastrointestinal infections (C)</p> Signup and view all the answers

Which type of immunodeficiency is caused by inherited defects of either nonspecific innate or specific adaptive immune defenses?

<p>Primary immunodeficiencies (D)</p> Signup and view all the answers

What is the most common cause of immunodeficiencies globally?

<p>Severe malnutrition (D)</p> Signup and view all the answers

What is the characteristic feature of X-linked agammaglobulinemia?

<p>Absence of immunoglobulin in the serum (B)</p> Signup and view all the answers

What is the cause of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (C)</p> Signup and view all the answers

What is the prevalence of selective IgA deficiency?

<p>1 in 800 (C)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiency worldwide?

<p>Severe malnutrition (C)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>Increased susceptibility to infection (B)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Impairs T-cell dependent antibody responses and cell-mediated immune responses (D)</p> Signup and view all the answers

What is the difference between primary and secondary immunodeficiencies?

<p>Primary immunodeficiencies are caused by inherited defects of either nonspecific innate or specific adaptive immune defenses, while secondary immunodeficiencies occur as a result of acquired impairment of function of B cells, T cells, or both (B)</p> Signup and view all the answers

What is the cause of secondary immunodeficiencies?

<p>Prolonged critical illness (A)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (D)</p> Signup and view all the answers

What is the feature of selective IgA deficiency?

<p>Predisposition to lung and gastrointestinal infections (C)</p> Signup and view all the answers

Which type of immunodeficiency is caused by inherited defects?

<p>Primary immunodeficiency (A)</p> Signup and view all the answers

What is the most common cause of immunodeficiencies globally?

<p>Malnutrition (A)</p> Signup and view all the answers

Which of the following is an example of primary immunodeficiency?

<p>Chronic granulomatous disease (A)</p> Signup and view all the answers

What is the characteristic feature of X-linked agammaglobulinemia?

<p>Absence of immunoglobulin in the serum (D)</p> Signup and view all the answers

Which immunodeficiency affects about one in 800 people?

<p>Selective IgA deficiency (A)</p> Signup and view all the answers

What is the main feature of severe combined immunodeficiency (SCID)?

<p>Impaired T-cell function (A)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiency worldwide?

<p>Malnutrition (D)</p> Signup and view all the answers

Which type of immunodeficiency is often reversible if the underlying cause is resolved?

<p>Secondary immunodeficiency (B)</p> Signup and view all the answers

What causes chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (D)</p> Signup and view all the answers

Which type of immunodeficiency is caused by acquired impairment of function?

<p>Secondary immunodeficiency (A)</p> Signup and view all the answers

What is the main consequence of primary immunodeficiency?

<p>Increased susceptibility to infection (D)</p> Signup and view all the answers

What is the main consequence of severe combined immunodeficiency (SCID)?

<p>Impaired T-cell function (D)</p> Signup and view all the answers

Which type of immunodeficiency affects about one in 800 people, predisposing them to lung and gastrointestinal infections?

<p>X-linked agammaglobulinemia (C)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (D)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>Increased susceptibility to infection (B)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Patients cannot develop immunological memory (A)</p> Signup and view all the answers

What is the difference between primary and secondary immunodeficiencies?

<p>Primary immunodeficiencies are caused by inherited defects of either nonspecific innate or specific adaptive immune defenses, while secondary immunodeficiencies occur as a result of acquired impairment of function of B cells, T cells, or both (D)</p> Signup and view all the answers

What is the cause of secondary immunodeficiencies?

<p>Acquired impairment of function of B cells, T cells, or both (B)</p> Signup and view all the answers

What is the prevalence of selective IgA deficiency?

<p>About one in 800 people (C)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiency worldwide?

<p>Malnutrition (D)</p> Signup and view all the answers

What is the characteristic feature of X-linked agammaglobulinemia?

<p>Absence of immunoglobulin in the serum (B)</p> Signup and view all the answers

What is the feature of patients with chronic granulomatous disease (CGD)?

<p>Chronic local inflammation called a granuloma (B)</p> Signup and view all the answers

Which type of immunodeficiency is caused by inherited defects of either nonspecific innate or specific adaptive immune defenses?

<p>Primary immunodeficiency (D)</p> Signup and view all the answers

What is the feature of patients with severe combined immunodeficiency (SCID)?

<p>Patients cannot develop immunological memory (C)</p> Signup and view all the answers

What is the most common cause of immunodeficiencies in developed countries?

<p>Inherited defects (C)</p> Signup and view all the answers

Which type of immunodeficiency affects about one in 800 people and predisposes them to lung and gastrointestinal infections?

<p>Selective IgA deficiency (A)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (A)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>Increased susceptibility to infection (D)</p> Signup and view all the answers

Which type of immunodeficiency impairs T-cell dependent antibody responses and cell-mediated immune responses and patients cannot develop immunological memory?

<p>Severe combined immunodeficiency (C)</p> Signup and view all the answers

What is the difference between primary and secondary immunodeficiencies?

<p>Primary immunodeficiencies are caused by inherited defects, while secondary immunodeficiencies are acquired (A)</p> Signup and view all the answers

What is the feature of X-linked agammaglobulinemia?

<p>Absence of immunoglobulin in the serum (A)</p> Signup and view all the answers

What is the prevalence of selective IgA deficiency?

<p>1 in 800 (D)</p> Signup and view all the answers

Which type of immunodeficiency is caused by defects in the NADPH oxidase system of phagocytic cells, leading to chronic local inflammation called a granuloma?

<p>Chronic granulomatous disease (B)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Impaired T-cell dependent antibody responses and cell-mediated immune responses (A)</p> Signup and view all the answers

What is the cause of secondary immunodeficiencies?

<p>Acquired impairment of function of B cells, T cells, or both (D)</p> Signup and view all the answers

Which type of immunodeficiency affects about one in 800 people and predisposes them to lung and gastrointestinal infections?

<p>Selective IgA deficiency (B)</p> Signup and view all the answers

Which type of immunodeficiency affects about one in 800 people, predisposing them to lung and gastrointestinal infections?

<p>Primary immunodeficiency (B)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (D)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>They have an increased susceptibility to infection (D)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Impaired T-cell dependent antibody responses (D)</p> Signup and view all the answers

What is the most common cause of primary immunodeficiencies in developed countries?

<p>Inherited defects (D)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiencies in developed countries?

<p>Systemic disorders (C)</p> Signup and view all the answers

Which immunodeficiency is characterized by the absence of immunoglobulin in the serum, leading to recurrent infections almost exclusively due to extracellular pathogens?

<p>X-linked agammaglobulinemia (B)</p> Signup and view all the answers

What is the difference between primary and secondary immunodeficiencies?

<p>Primary immunodeficiencies are caused by inherited defects, while secondary immunodeficiencies are acquired (D)</p> Signup and view all the answers

What is the cause of chronic local inflammation called a granuloma in chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (C)</p> Signup and view all the answers

Which immunodeficiency affects about one in 800 people?

<p>Selective IgA deficiency (D)</p> Signup and view all the answers

Which type of immunodeficiency is often reversible if the underlying cause is resolved?

<p>Secondary immunodeficiency (C)</p> Signup and view all the answers

What is the feature of patients with severe combined immunodeficiency (SCID)?

<p>They have an increased susceptibility to infection (B)</p> Signup and view all the answers

What is the most common cause of immunodeficiencies in developed countries?

<p>Inherited defects (B)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (B)</p> Signup and view all the answers

What is the prevalence of selective IgA deficiency?

<p>1 in 800 people (A)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>Increased susceptibility to infection (A)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Cannot develop immunological memory (D)</p> Signup and view all the answers

What is the cause of secondary immunodeficiencies?

<p>Prolonged critical illness (C)</p> Signup and view all the answers

What is the characteristic feature of X-linked agammaglobulinemia?

<p>Absence of immunoglobulin in the serum (A)</p> Signup and view all the answers

What is the difference between primary and secondary immunodeficiencies?

<p>Primary immunodeficiencies are caused by inherited defects, while secondary immunodeficiencies are acquired (C)</p> Signup and view all the answers

What is the feature of patients with chronic granulomatous disease (CGD)?

<p>Increased susceptibility to infection (A)</p> Signup and view all the answers

What is the feature of patients with selective IgA deficiency?

<p>Increased susceptibility to infection (A)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiency worldwide?

<p>Severe malnutrition (D)</p> Signup and view all the answers

What is the feature of patients with severe combined immunodeficiency (SCID)?

<p>Cannot develop immunological memory (A)</p> Signup and view all the answers

What is the cause of primary immunodeficiencies?

<p>Inherited defects of either nonspecific innate or specific adaptive immune defenses (B)</p> Signup and view all the answers

Which type of immunodeficiency is characterized by the absence of immunoglobulin in the serum?

<p>X-linked agammaglobulinemia (C)</p> Signup and view all the answers

What is the prevalence of selective IgA deficiency?

<p>1 in 800 people (B)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>Increased susceptibility to infection (D)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Impairs T-cell dependent antibody responses and cell-mediated immune responses (C)</p> Signup and view all the answers

What is the cause of secondary immunodeficiencies?

<p>Acquired impairment of function of B cells, T cells, or both (D)</p> Signup and view all the answers

Which immunodeficiency is caused by defects in the NADPH oxidase system of phagocytic cells?

<p>Chronic granulomatous disease (C)</p> Signup and view all the answers

What is the most common cause of immunodeficiencies in developed countries?

<p>Inherited defects (D)</p> Signup and view all the answers

Which type of immunodeficiency affects both innate and adaptive immunity?

<p>Secondary immunodeficiencies (C)</p> Signup and view all the answers

What is the characteristic feature of selective IgA deficiency?

<p>Increased susceptibility to extracellular pathogens (D)</p> Signup and view all the answers

Which type of immunodeficiency impairs the function of T cells only?

<p>Severe combined immunodeficiency (A)</p> Signup and view all the answers

Which type of immunodeficiency is often reversible if the underlying cause is resolved?

<p>Secondary immunodeficiencies (D)</p> Signup and view all the answers

Which type of immunodeficiency affects about one in 800 people, predisposing them to lung and gastrointestinal infections?

<p>Selective IgA deficiency (A)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (D)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>Increased susceptibility to infection (A)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Inability to develop immunological memory (D)</p> Signup and view all the answers

What is the most common cause of immunodeficiencies in developed countries?

<p>Inherited defects (C)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiencies in developed countries?

<p>Immunosuppressive treatments (A)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiencies in developing countries?

<p>Malnutrition (D)</p> Signup and view all the answers

What is the characteristic feature of X-linked agammaglobulinemia?

<p>Absence of immunoglobulin in the serum (B)</p> Signup and view all the answers

What is the characteristic feature of selective IgA deficiency?

<p>Impaired T-cell dependent antibody responses (D)</p> Signup and view all the answers

What type of immunodeficiency can be caused by systemic disorders?

<p>Secondary immunodeficiency (D)</p> Signup and view all the answers

What type of immunodeficiency is caused by inherited defects of either nonspecific innate or specific adaptive immune defenses?

<p>Primary immunodeficiency (D)</p> Signup and view all the answers

What is the feature of patients with chronic granulomatous disease (CGD)?

<p>Chronic local inflammation called a granuloma (B)</p> Signup and view all the answers

What is the primary cause of immunodeficiencies globally?

<p>Severe malnutrition (A)</p> Signup and view all the answers

Which type of immunodeficiency affects about one in 800 people?

<p>Selective IgA deficiency (A)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (D)</p> Signup and view all the answers

What is the feature of patients born with primary immunodeficiency?

<p>Increased susceptibility to infection (C)</p> Signup and view all the answers

What is the characteristic feature of X-linked agammaglobulinemia?

<p>Absence of immunoglobulin in the serum (A)</p> Signup and view all the answers

What is the feature of selective IgA deficiency?

<p>Predisposition to lung and gastrointestinal infections (D)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Impaired T-cell dependent antibody responses and cell-mediated immune responses (D)</p> Signup and view all the answers

What is the cause of secondary immunodeficiencies?

<p>Systemic disorders (A)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiency worldwide?

<p>Severe malnutrition (C)</p> Signup and view all the answers

What is the difference between primary and secondary immunodeficiencies?

<p>Primary immunodeficiencies are inherited, while secondary immunodeficiencies are acquired (C)</p> Signup and view all the answers

Which type of immunodeficiency leads to recurrent infections almost exclusively due to extracellular pathogens?

<p>X-linked agammaglobulinemia (B)</p> Signup and view all the answers

Which type of immunodeficiency impairs T-cell dependent antibody responses and cell-mediated immune responses?

<p>Severe combined immunodeficiency (D)</p> Signup and view all the answers

What is the most common cause of immunodeficiencies in developed countries?

<p>Inherited defects (D)</p> Signup and view all the answers

What is the main consequence of primary immunodeficiencies?

<p>Increased susceptibility to infection (A)</p> Signup and view all the answers

Which of the following is an example of primary immunodeficiency?

<p>Severe combined immunodeficiency disease (C)</p> Signup and view all the answers

What is the cause of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (C)</p> Signup and view all the answers

Which of the following is a characteristic feature of X-linked agammaglobulinemia?

<p>Absence of immunoglobulin in the serum (A)</p> Signup and view all the answers

What is the prevalence of selective IgA deficiency?

<p>About one in 800 people (A)</p> Signup and view all the answers

What is the feature of severe combined immunodeficiency (SCID)?

<p>Impairs T-cell dependent antibody responses and cell-mediated immune responses (C)</p> Signup and view all the answers

What is the main cause of secondary immunodeficiencies worldwide?

<p>Severe malnutrition (C)</p> Signup and view all the answers

What is the feature of patients with secondary immunodeficiencies?

<p>Impaired function of B cells, T cells, or both (D)</p> Signup and view all the answers

Are secondary immunodeficiencies reversible?

<p>Yes, if the underlying cause is resolved (D)</p> Signup and view all the answers

Which of the following is NOT an example of primary immunodeficiency?

<p>HIV/AIDS (D)</p> Signup and view all the answers

What is the most common cause of immunodeficiencies globally?

<p>Malnutrition (D)</p> Signup and view all the answers

What is the primary cause of immunodeficiencies globally?

<p>Malnutrition (A)</p> Signup and view all the answers

What is the characteristic feature of chronic granulomatous disease (CGD)?

<p>Defects in the NADPH oxidase system of phagocytic cells (C)</p> Signup and view all the answers

Which immunodeficiency impairs T-cell dependent antibody responses and cell-mediated immune responses?

<p>Severe combined immunodeficiency (A)</p> Signup and view all the answers

What is the prevalence of selective IgA deficiency?

<p>1 in 800 people (C)</p> Signup and view all the answers

Which type of immunodeficiency is caused by acquired impairment of function of B cells, T cells, or both?

<p>Secondary immunodeficiency (B)</p> Signup and view all the answers

What is the most common cause of secondary immunodeficiency worldwide?

<p>Malnutrition (A)</p> Signup and view all the answers

Which immunodeficiency is characterized by the absence of immunoglobulin in the serum?

<p>X-linked agammaglobulinemia (B)</p> Signup and view all the answers

Which immunodeficiency predisposes individuals to lung and gastrointestinal infections?

<p>Selective IgA deficiency (A)</p> Signup and view all the answers

Which immunodeficiency leads to chronic local inflammation called a granuloma?

<p>Chronic granulomatous disease (A)</p> Signup and view all the answers

Which immunodeficiency impairs the ability to develop immunological memory?

<p>Severe combined immunodeficiency (C)</p> Signup and view all the answers

Which type of immunodeficiency is often reversible if the underlying cause is resolved?

<p>Secondary immunodeficiency (A)</p> Signup and view all the answers

What is the primary cause of immunodeficiencies in developed countries?

<p>Inherited defects (A)</p> Signup and view all the answers

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