Apoptosis Mechanism Quiz
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Questions and Answers

What is the main purpose of apoptosis in eukaryotic cells?

  • To induce an inflammatory response
  • To prevent cell turnover
  • To promote cell growth
  • To eliminate unwanted and defective cells (correct)

Which of the following disorders can result from improper regulation of apoptosis?

  • Hypertension
  • Cancer (correct)
  • Diabetes
  • Osteoporosis

What type of signals can trigger apoptosis?

  • A wide variety of signals including Fas ligand, tumor necrosis factor, and growth factor withdrawal (correct)
  • Only Fas ligand
  • Only growth factor withdrawal
  • Only viral or bacterial infection

What is the main role of caspases in the apoptotic process?

<p>To act as effectors of the cell death pathway (A)</p> Signup and view all the answers

Which of the following proteins can be cleaved by activated caspases during apoptosis?

<p>Lamins (C)</p> Signup and view all the answers

What happens to cells during normal development and turnover?

<p>They undergo apoptosis (A)</p> Signup and view all the answers

What is the main purpose of balancing cell loss and cell gain in metazoans?

<p>To maintain the complex architecture of tissues (A)</p> Signup and view all the answers

What is a significant similarity between mitosis and apoptosis?

<p>Both processes involve chromatin condensation (B)</p> Signup and view all the answers

What sets apoptotic cells apart from cells undergoing mitosis?

<p>Apoptotic cells display a nucleosomal ladder pattern during DNA degradation (B)</p> Signup and view all the answers

How can manipulation of the cell cycle affect the apoptotic response?

<p>It can prevent or induce an apoptotic response depending on the cellular context (C)</p> Signup and view all the answers

What role do proliferative proteins play in relation to apoptosis?

<p>They may act to sensitize cells to apoptosis (C)</p> Signup and view all the answers

What is the mechanism by which apoptotic cells are typically removed from the body?

<p>Phagocytosis by adjacent cells or macrophages (B)</p> Signup and view all the answers

What happens to DNA in apoptotic cells that sets them apart from mitotic cells?

<p>DNA is degraded at internucleosomal linker sites, yielding DNA fragments in multiples of 180 bp (A)</p> Signup and view all the answers

What is a common feature of both mitosis and apoptosis?

<p>Cells lose substrate attachment during both processes (D)</p> Signup and view all the answers

Why is it important to balance cell loss and cell gain in metazoans?

<p>To maintain tissue architecture and allow adaptation to changing circumstances (C)</p> Signup and view all the answers

What is the relationship between genes involved in cell cycle progression and apoptosis regulation?

<p>Genes involved in cell cycle progression may regulate apoptosis (C)</p> Signup and view all the answers

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