APAE Antibiotics Course Overview Quiz
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Questions and Answers

What percentage of PCN-allergic patients are allergic to cephalosporins?

  • 50-60%
  • Less than 1%
  • 90-98%
  • 2-10% (correct)

    • Which type of PCN reaction would contraindicate giving a cephalosporin?

  • Type IV hypersensitivity
  • Anaphylaxis (correct)
  • Morbilliform rash
  • Hives

    • What type of reaction is associated with hives in response to penicillin (PCN)?

  • Type IV hypersensitivity
  • Type III hypersensitivity
  • Type II hypersensitivity
  • IgE-mediated, Type I reaction (correct)

    • In terms of allergic reactions, why does Rule 3 suggest giving a cephalosporin?

    <p>Morbilliform rash indicates safety for cephalosporin use</p> Signup and view all the answers

    Which type of PCN-allergic patients can safely take cephalosporins according to the text?

    <p>Those allergic to the pink pentagon</p> Signup and view all the answers

    What is the suggested course of action if the patient had hives following a penicillin reaction?

    <p>Consider giving a cephalosporin with caution</p> Signup and view all the answers

    Which type of organisms are classified as gram-positive?

    <p>Staphylococcus</p> Signup and view all the answers

    Which organisms fall under the category of gram-negative bugs?

    <p>Neisseria gonorrhoeae</p> Signup and view all the answers

    What is the significance of a beta-lactam ring in antibiotics?

    <p>It interacts with penicillin-binding proteins.</p> Signup and view all the answers

    Why is printing multiple copies of the Course Manual content considered a violation of copyright?

    <p>It violates the terms of use set by the provider.</p> Signup and view all the answers

    Which antibiotic class is known for having a wide antimicrobial spectrum?

    <p>Fluoroquinolones</p> Signup and view all the answers

    Which antibiotic is a good choice for Mycoplasma and community-acquired-MRSA?

    <p>Doxycycline</p> Signup and view all the answers

    Which antibiotic is effective against Legionella sp.?

    <p>Clarithromycin</p> Signup and view all the answers

    Which antibiotic is a good choice for Streptococcus and atypical pathogens?

    <p>Azithromycin</p> Signup and view all the answers

    Which antibiotic is not effective against Enterococcus and Listeria?

    <p>Doxycycline</p> Signup and view all the answers

    Which antibiotic is a good choice for Proteus mirabilis but not for Staph: MSSA?

    <p>Cefdinir</p> Signup and view all the answers

    Which antibiotic is indicated for infections caused by Klebsiella?

    <p>Cefixime</p> Signup and view all the answers

    Can amoxicillin effectively eliminate Drug-resistant Strep pneumoniae (DRSP)?

    <p>No, DRSP is resistant to amoxicillin</p> Signup and view all the answers

    How can you identify if a bacterial strain produces beta-lactamase?

    <p>By using a biochemical test to detect the enzyme</p> Signup and view all the answers

    What is the maximum adult dose for Amoxicillin/Clavulanic acid (Augmentin)?

    <p>2000 mg twice daily</p> Signup and view all the answers

    Which of the following organisms are NOT typically susceptible to Amoxicillin/Clavulanic acid (Augmentin)?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    Is TMP-SMX (Bactrim, Septra) effective against Strep organisms?

    <p>No, TMP-SMX has no activity against Streptococcus species</p> Signup and view all the answers

    If a patient is allergic to penicillin, can you safely prescribe a cephalosporin?

    <p>Yes, because being allergic to penicillin does not mean they are allergic to cephalosporin</p> Signup and view all the answers

    If a patient is allergic to the pink pentagon in penicillin, can they safely take a cephalosporin?

    <p>Yes, because the pink pentagon is not present in cephalosporins</p> Signup and view all the answers

    If a patient is allergic to the blue box in penicillin, can they safely take a cephalosporin?

    <p>Yes, because the blue box is not present in cephalosporins</p> Signup and view all the answers

    Do all beta-lactam antibiotics trigger the same type of allergic reactions?

    <p>No, because different beta-lactam antibiotics have different side chains that impact allergenicity</p> Signup and view all the answers

    Can a patient who is allergic to both penicillin and cephalosporin be prescribed another class of antibiotics?

    <p>No, because allergies to penicillins and cephalosporins usually indicate cross-reactivity with other classes of antibiotics</p> Signup and view all the answers

    Is being allergic to beta-lactam antibiotics common among patients?

    <p>No, beta-lactam allergies are very rare and affect only a small percentage of patients</p> Signup and view all the answers

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