APAE Antibiotics Course Overview Quiz

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Questions and Answers

What percentage of PCN-allergic patients are allergic to cephalosporins?

  • 50-60%
  • Less than 1%
  • 90-98%
  • 2-10% (correct)

Which type of PCN reaction would contraindicate giving a cephalosporin?

  • Type IV hypersensitivity
  • Anaphylaxis (correct)
  • Morbilliform rash
  • Hives

What type of reaction is associated with hives in response to penicillin (PCN)?

  • Type IV hypersensitivity
  • Type III hypersensitivity
  • Type II hypersensitivity
  • IgE-mediated, Type I reaction (correct)

In terms of allergic reactions, why does Rule 3 suggest giving a cephalosporin?

<p>Morbilliform rash indicates safety for cephalosporin use (A)</p> Signup and view all the answers

Which type of PCN-allergic patients can safely take cephalosporins according to the text?

<p>Those allergic to the pink pentagon (B)</p> Signup and view all the answers

What is the suggested course of action if the patient had hives following a penicillin reaction?

<p>Consider giving a cephalosporin with caution (D)</p> Signup and view all the answers

Which type of organisms are classified as gram-positive?

<p>Staphylococcus (C)</p> Signup and view all the answers

Which organisms fall under the category of gram-negative bugs?

<p>Neisseria gonorrhoeae (B)</p> Signup and view all the answers

What is the significance of a beta-lactam ring in antibiotics?

<p>It interacts with penicillin-binding proteins. (C)</p> Signup and view all the answers

Why is printing multiple copies of the Course Manual content considered a violation of copyright?

<p>It violates the terms of use set by the provider. (D)</p> Signup and view all the answers

Which antibiotic class is known for having a wide antimicrobial spectrum?

<p>Fluoroquinolones (C)</p> Signup and view all the answers

Which antibiotic is a good choice for Mycoplasma and community-acquired-MRSA?

<p>Doxycycline (D)</p> Signup and view all the answers

Which antibiotic is effective against Legionella sp.?

<p>Clarithromycin (A)</p> Signup and view all the answers

Which antibiotic is a good choice for Streptococcus and atypical pathogens?

<p>Azithromycin (B)</p> Signup and view all the answers

Which antibiotic is not effective against Enterococcus and Listeria?

<p>Doxycycline (C)</p> Signup and view all the answers

Which antibiotic is a good choice for Proteus mirabilis but not for Staph: MSSA?

<p>Cefdinir (D)</p> Signup and view all the answers

Which antibiotic is indicated for infections caused by Klebsiella?

<p>Cefixime (C)</p> Signup and view all the answers

Can amoxicillin effectively eliminate Drug-resistant Strep pneumoniae (DRSP)?

<p>No, DRSP is resistant to amoxicillin (A)</p> Signup and view all the answers

How can you identify if a bacterial strain produces beta-lactamase?

<p>By using a biochemical test to detect the enzyme (B)</p> Signup and view all the answers

What is the maximum adult dose for Amoxicillin/Clavulanic acid (Augmentin)?

<p>2000 mg twice daily (A)</p> Signup and view all the answers

Which of the following organisms are NOT typically susceptible to Amoxicillin/Clavulanic acid (Augmentin)?

<p>Staphylococcus aureus (D)</p> Signup and view all the answers

Is TMP-SMX (Bactrim, Septra) effective against Strep organisms?

<p>No, TMP-SMX has no activity against Streptococcus species (D)</p> Signup and view all the answers

If a patient is allergic to penicillin, can you safely prescribe a cephalosporin?

<p>Yes, because being allergic to penicillin does not mean they are allergic to cephalosporin (D)</p> Signup and view all the answers

If a patient is allergic to the pink pentagon in penicillin, can they safely take a cephalosporin?

<p>Yes, because the pink pentagon is not present in cephalosporins (C)</p> Signup and view all the answers

If a patient is allergic to the blue box in penicillin, can they safely take a cephalosporin?

<p>Yes, because the blue box is not present in cephalosporins (C)</p> Signup and view all the answers

Do all beta-lactam antibiotics trigger the same type of allergic reactions?

<p>No, because different beta-lactam antibiotics have different side chains that impact allergenicity (A)</p> Signup and view all the answers

Can a patient who is allergic to both penicillin and cephalosporin be prescribed another class of antibiotics?

<p>No, because allergies to penicillins and cephalosporins usually indicate cross-reactivity with other classes of antibiotics (A)</p> Signup and view all the answers

Is being allergic to beta-lactam antibiotics common among patients?

<p>No, beta-lactam allergies are very rare and affect only a small percentage of patients (C)</p> Signup and view all the answers

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