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Questions and Answers
ما هو العامل الذي تسبّب في ضمور؟
ما هو العامل الذي تسبّب في ضمور؟
هل يمكن أن يكون ورم lipochondroma خبيثًا؟
هل يمكن أن يكون ورم lipochondroma خبيثًا؟
False
ما هو العضو الذي قد ينمو فيه ورم osteoma ؟
ما هو العضو الذي قد ينمو فيه ورم osteoma ؟
العظم
ما هو العامل الأساسي لتشخيص neurofibromatosis من النوع الأول ?
ما هو العامل الأساسي لتشخيص neurofibromatosis من النوع الأول ?
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طابق الأورام الحميدة التالية مع مواقع ظهورها في الفم :
طابق الأورام الحميدة التالية مع مواقع ظهورها في الفم :
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ما هي الخصائص التشخيصية لـ keratoacanthoma?
ما هي الخصائص التشخيصية لـ keratoacanthoma?
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هل neurofibromatosis هي مرض وراثي؟
هل neurofibromatosis هي مرض وراثي؟
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ما هي الخصائص الأساسية لورم fibroma?
ما هي الخصائص الأساسية لورم fibroma?
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ما هي الخلايا التي تُشكل ورم schwannoma؟
ما هي الخلايا التي تُشكل ورم schwannoma؟
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ما هو الورم الذي يُصيب عظم الوجه و العظم الذي يُشكل الفك الأسفل و العظم الذي يُشكل الفك الأعلى و الذي يُشكل نهاية العظم الذي يُشكل الفك الأسفل؟
ما هو الورم الذي يُصيب عظم الوجه و العظم الذي يُشكل الفك الأسفل و العظم الذي يُشكل الفك الأعلى و الذي يُشكل نهاية العظم الذي يُشكل الفك الأسفل؟
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هل الورم desmoplastic fibroma خبيث؟
هل الورم desmoplastic fibroma خبيث؟
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ما هي الخصائص المُشخصة لـ hemangioma of infancy؟
ما هي الخصائص المُشخصة لـ hemangioma of infancy؟
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ما هو الورم الذي ينمو في النسيج الضام الليثي و يُشكل أكثر من 80% من حالات الأورام في الفم و الوجه و الرقبة؟
ما هو الورم الذي ينمو في النسيج الضام الليثي و يُشكل أكثر من 80% من حالات الأورام في الفم و الوجه و الرقبة؟
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Is neurofibromatosis a malignant disease؟
Is neurofibromatosis a malignant disease؟
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What are the characteristic symptoms of sturge-weber syndrome?
What are the characteristic symptoms of sturge-weber syndrome?
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What are the characteristics of melanocytic nevi?
What are the characteristics of melanocytic nevi?
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Study Notes
Benign Tumors of the Oral Cavity
- A neoplasm is a new growth forming an abnormal mass of tissue, characterized by autonomy (independent growth), uncontrolled proliferation, and lack of regression or atrophy when the initiating factor is removed.
Classification of Neoplasms
-
Based on Histogenesis (Tissue Origin):
- Epithelial origin
- Mesenchymal origin
-
Based on Behavior:
- Benign origin
- Malignant origin
Differences Between Benign and Malignant Neoplasms
-
Clinical and Gross Appearance:
- Benign: Slow and gradual growth, expansile, infrequent ulceration, usually with intact surface.
- Malignant: Rapid growth, infiltrative, frequent ulceration due to necrosis and hemorrhage.
-
Metastasis:
- Benign: Never metastasizes.
- Malignant: Frequent metastasis.
-
Size:
- Benign: Smaller compared to malignant lesions
- Malignant: Larger compared to benign
-
Borders:
- Benign: Well-defined, smooth edges.
- Malignant: Ill-defined, irregular edges.
-
Fixation:
- Benign: Not fixed to surrounding tissues.
- Malignant: Fixed to surrounding tissues
-
Recurrence:
- Benign: Does not recur after surgical removal.
- Malignant: Often recurs.
Benign Epithelial Tumors
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Squamous Cell Papilloma: A benign neoplasm of stratified squamous epithelium.
- Clinical Features: Exophytic growth, often finger-like projections, variable color and consistency.
- Histological Features: Hyperplastic stratified squamous epithelium.
-
Keratoacanthoma: Benign epithelial tumor resembling squamous cell carcinoma.
- Clinical Features: Elevated firm nodule with central keratin-filled crater, usually asymptomatic.
- Pathogenesis: Unknown but possibly related to UV radiation.
- Clinical Course: Usually regresses spontaneously within 6-8 weeks.
- Histological Features: Hyperplastic stratified squamous epithelium with keratin plugging, possible keratinocyte atypia.
Benign Mesenchymal Tumors
-
Fibroma: Benign tumor of fibrous connective tissue.
- Clinical Features: Most common oral cavity tumor, painless, may be from reactive hyperplasia.
- Histological Features: Dense fibrous tissue, with variable cellularity.
-
Desmoid-Type Fibromatosis: A locally infiltrative, non-metastasizing myofibroblastic neoplasm.
- Etiology: May be related to trauma, genetic dysregulation, or Gardner syndrome.
- Clinical Features: Painless swelling, may become large and invade surrounding structures.
-
Solitary Fibrous Tumor: A fibroblastic tumor often with a well-defined border and a prominent, branched staghorn vasculature.
- Clinical Features: Typically slow-growing, painless, and well-circumscribed in the oral cavity.
- Histological Features: Spindle cells arranged haphazardly, variable cellularity and collagen content, prominent staghorn vasculature.
-
Lipomas: Benign tumors of adipose tissue, often in deep oral sites.
- Clinical Features: Painless, often lobulated, yellowish masses.
- Histological Features: Formed of mature fat cells with clear cytoplasm, compressed nuclei, and cellular capsule.
-
Myomas: Benign tumors of smooth muscle (leiomyomas) or striated muscle (rhabdomyomas).
- Clinical Features: Painless, slow-growing masses.
- Histological Features: Smooth muscle cells arranged in interlacing bundles (leiomyoma) or striated muscle cells
-
Neural Tumors (Granular Cell Tumors, Neurofibromas, Schwannomas): Lesions of neural crest cell origin.
- Clinical Features: Usually slow-growing, painless nodules.
- Histological Features: vary by tumor type but could include sheets of large, round cells with granular cytoplasm (G.C.T), characteristic fascicles of spindle-shaped cells (N,), or a biphasic pattern with a cellular and acellular component (Schwannomas).
-
Vascular Tumors:
- Hemangioma of Infancy: Rapid growth phase, followed by involution
- Congenital Hemangioma: Present at birth, non-involuting and involuting types.
-
Vascular Malformations: Irregular development.
- Capillary: port-wine stain (Sturge-Weber Syndrome)
- Venous: blue dilated vein; usually present at birth.
- Lymphatic: Cystic hygroma, often multilocular cysts.
- Intrabony: a vascular malformation that can be found in the bone.
-
Melanocytic Nevi: Tumor-like pigmented lesions.
- Acquired: Common mole is a proliferation of nevus cells arising typically at the dermal-epidermal junction, intraoral lesions are uncommon.
- Congenital: Present at birth, can be small or very large
- Clinical features and histological features vary for each type
-
Maxillofacial Bone & Cartilage Tumors:
- Osteoma: Benign bone tumor, often solitary, well-defined radiological appearance.
- Osteochondroma: Cartilage-capped bony projection, usually arising from the cortex.
- Desmoplastic Fibroma: Locally aggressive bone tumor, often in the mandible
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Description
يتناول هذا الاختبار أورام الفم الحميدة، وتصنيفها بناءً على المنشأ السليلي وسلوكها. كما يستعرض الفروق بين الأورام الحميدة والخبيثة من حيث النمو، والتأثير، والانتشار. تعد هذه المعلومات ضرورية لفهم طبيعة الأورام ومراقبتها في المجال الطبي.