14 Questions
What is the duration of each transient required for a discharge to qualify as an interictal epileptiform discharge (IED)?
Between 100 ms and 200 ms
Which type of EEG abnormalities are associated with epilepsy at rates sufficient to be clinically useful?
Interictal epileptiform discharges
What is the previous name for lateralized periodic discharges (LPDs)?
Periodic lateralized epileptiform discharges (PLEDs)
Which of the following conditions have been associated with IEDs, even in the absence of accompanying seizures?
High drug levels of tricyclic antidepressants
Which of the following drugs is NOT associated with IEDs, even in the absence of accompanying seizures?
Selective serotonin reuptake inhibitors (SSRIs)
What can inexperienced interpreters of EEG potentially do that can limit the specificity of the findings?
Misread EEGs and underdiagnose IEDs
Which of the following is a characteristic of sharp waves?
Duration between 70 and 200 ms
What is a distinguishing feature of most IEDs at the scalp?
Negative polarity
What is the sensitivity of an IED finding on a first 'routine' EEG?
Between 20% and 55%
What is the probability of seizure recurrence in patients with normal EEGs after a first unprovoked seizure?
27%
Which epilepsy syndrome is almost invariably associated with the presence of IEDs?
Landau-Kleffner syndrome
What technique can be used to increase the yield of IEDs on an interictal EEG?
Photic stimulation
What is the prevalence of IEDs in healthy children?
3.5 to 6.5 percent
What is the specificity of IEDs in patients without a history of seizures?
0.5 percent
Test your knowledge on the impact of antiseizure medication on IEDs and EEG abnormalities in epilepsy syndromes with this informative quiz. Keywords: Diazepam, phenobarbital, IEDs, chronic therapy, antiseizure medication, withdrawal, EEG, epilepsy syndromes.
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