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Questions and Answers
Which of the following is NOT a mechanism of action of antiseizure drugs?
Which of the following is NOT a mechanism of action of antiseizure drugs?
- Enhancement of GABAergic (inhibitory) transmission
- Diminution of excitatory (usually glutamatergic) transmission
- Increase in dopamine levels in the brain (correct)
- Modification of ionic conductance
Which antiseizure drug produces enhancement of GABA-mediated inhibition?
Which antiseizure drug produces enhancement of GABA-mediated inhibition?
- Carbamazepine
- Phenytoin (correct)
- Ethosuximide
- Lamotrigine
Which antiseizure drug has an impotent effect on the T-type calcium channels in thalamic neurons?
Which antiseizure drug has an impotent effect on the T-type calcium channels in thalamic neurons?
- Lamotrigine
- Carbamazepin
- Phenytoin
- Ethosuximide (correct)
Which antiseizure drug inhibits central effects of excitatory amino acids?
Which antiseizure drug inhibits central effects of excitatory amino acids?
Which antiseizure drug produces a voltage-dependent inactivation of sodium channels?
Which antiseizure drug produces a voltage-dependent inactivation of sodium channels?
Which drug is indicated for partial and generalized tonic-clonic seizures?
Which drug is indicated for partial and generalized tonic-clonic seizures?
Phenytoin is used for the treatment of:
Phenytoin is used for the treatment of:
Which adverse effect is dose-related and caused by phenytoin?
Which adverse effect is dose-related and caused by phenytoin?
Which antiseizure drug induces hepatic microsomal enzymes?
Which antiseizure drug induces hepatic microsomal enzymes?
Which antiseizure drug is the drug of choice for partial seizures?
Which antiseizure drug is the drug of choice for partial seizures?
The mechanism of action of carbamazepine appears to be similar to that of:
The mechanism of action of carbamazepine appears to be similar to that of:
Which antiseizure drug is also effective in treating trigeminal neuralgia?
Which antiseizure drug is also effective in treating trigeminal neuralgia?
The most common dose-related adverse effects of carbamazepine are:
The most common dose-related adverse effects of carbamazepine are:
Which antiseizure drug is the drug of choice for status epilepticus in infants and children?
Which antiseizure drug is the drug of choice for status epilepticus in infants and children?
Barbiturates are used in the emergency treatment of status epilepticus in infants and children because of:
Barbiturates are used in the emergency treatment of status epilepticus in infants and children because of:
Which antiseizure drug binds to an allosteric regulatory site on the GABA-BZ receptor and increases the duration of the Cl- channels openings?
Which antiseizure drug binds to an allosteric regulatory site on the GABA-BZ receptor and increases the duration of the Cl- channels openings?
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