Antiseizure Drugs Mechanism Quiz

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Which of the following is NOT a mechanism of action of antiseizure drugs?

Enhancement of GABAergic (inhibitory) transmission

Diminution of excitatory (usually glutamatergic) transmission

Increase in dopamine levels in the brain (correct)

Modification of ionic conductance

Which antiseizure drug produces enhancement of GABA-mediated inhibition?

Carbamazepine

Phenytoin (correct)

Ethosuximide

Lamotrigine

Which antiseizure drug has an impotent effect on the T-type calcium channels in thalamic neurons?

Lamotrigine

Carbamazepin

Phenytoin

Ethosuximide (correct)

Which antiseizure drug inhibits central effects of excitatory amino acids?

Tiagabine Signup and view all the answers

Which antiseizure drug produces a voltage-dependent inactivation of sodium channels?

Lamotrigine Signup and view all the answers

Which drug is indicated for partial and generalized tonic-clonic seizures?

Valproate Signup and view all the answers

Phenytoin is used for the treatment of:

Grand mal epilepsy Signup and view all the answers

Which adverse effect is dose-related and caused by phenytoin?

Gingival hyperplasia Signup and view all the answers

Which antiseizure drug induces hepatic microsomal enzymes?

Phenytoin Signup and view all the answers

Which antiseizure drug is the drug of choice for partial seizures?

Carbamazepine Signup and view all the answers

The mechanism of action of carbamazepine appears to be similar to that of:

Phenytoin Signup and view all the answers

Which antiseizure drug is also effective in treating trigeminal neuralgia?

Carbamazepine Signup and view all the answers

The most common dose-related adverse effects of carbamazepine are:

Diplopia, ataxia, and nausea Signup and view all the answers

Which antiseizure drug is the drug of choice for status epilepticus in infants and children?

Phenobarbital sodium Signup and view all the answers

Barbiturates are used in the emergency treatment of status epilepticus in infants and children because of:

Short onset and duration of action Signup and view all the answers

Which antiseizure drug binds to an allosteric regulatory site on the GABA-BZ receptor and increases the duration of the Cl- channels openings?

Topiramate Signup and view all the answers

Antiseizure Drugs Mechanism Quiz

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