Antiparkinsonian Drugs
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Questions and Answers

Which part of the brain is correlated with a reduction in the activity of inhibitory dopaminergic neurons in Parkinson's disease?

  • Substantia nigra and corpus striatum (correct)
  • Frontal lobe and parietal lobe
  • Temporal lobe and occipital lobe
  • Cerebellum and hypothalamus
  • Which of the following is not listed as a possible etiology of Parkinson's disease?

  • Viral encephalitis
  • Excessive dopamine production (correct)
  • Drug-induced
  • Cerebral ischemia
  • Which drug is mentioned as an example of a medication that reduces the amount of dopamine in the brain?

  • Ibuprofen
  • Reserpine (correct)
  • Aspirin
  • Acetaminophen
  • Which symptom of Parkinson's disease involves a characteristic fast shuffling gait and difficulty in starting and stopping while walking?

    <p>Postural abnormalities</p> Signup and view all the answers

    What is the main imbalance between neurons that contributes to many symptoms of Parkinson's disease?

    <p>Excitatory cholinergic neurons and greatly diminished inhibitory dopaminergic neurons</p> Signup and view all the answers

    Study Notes

    Parkinson's Disease

    • The reduction in the activity of inhibitory dopaminergic neurons in Parkinson's disease is correlated with the substantia nigra part of the brain.

    Etiology

    • Pesticide exposure is not listed as a possible etiology of Parkinson's disease.

    Medications

    • Reserpine is an example of a medication that reduces the amount of dopamine in the brain.

    Symptoms

    • Festinating gait involves a characteristic fast shuffling gait and difficulty in starting and stopping while walking.

    Pathophysiology

    • The main imbalance between neurons that contributes to many symptoms of Parkinson's disease is an imbalance between dopamine and acetylcholine.

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    Description

    Test your knowledge of antiparkinsonian drugs with this quiz on pharmacology. Learn about medications used to manage the symptoms of Parkinson's disease, a progressive disorder affecting muscle movement, often in the elderly. Explore the role of dopaminergic neurons in the basal ganglia and substantia nigra, and their correlation with motor control.

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