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Questions and Answers
What is the mechanism of action of sulfonamides?
What is the mechanism of action of sulfonamides?
- Inactivating bacterial enzymes
- Disrupting cell wall formation
- Inhibiting protein synthesis
- Blocking folic acid synthesis (correct)
Why can PABA in multivitamins cause therapy failure when taking sulfonamide antibiotics?
Why can PABA in multivitamins cause therapy failure when taking sulfonamide antibiotics?
- It competes with sulfonamides for their target (correct)
- It increases bacterial resistance
- It enhances the effect of antibiotics
- It boosts the immune system against bacteria
Which of the following bacterial species is not susceptible to sulfonamides?
Which of the following bacterial species is not susceptible to sulfonamides?
- E. coli
- Staphylococcus aureus (correct)
- Chlamydia
- Nocardia
Why are sulfonamides considered antimetabolites?
Why are sulfonamides considered antimetabolites?
In which bacterial species would sulfonamides likely be effective due to their mechanism of action?
In which bacterial species would sulfonamides likely be effective due to their mechanism of action?
When tetracycline is combined with gentamicin, what is the expected result?
When tetracycline is combined with gentamicin, what is the expected result?
What type of activity is exhibited when ampicillin is combined with vancomycin against E. coli?
What type of activity is exhibited when ampicillin is combined with vancomycin against E. coli?
Based on the text, what is a resistant mechanism to cell wall or membrane agents?
Based on the text, what is a resistant mechanism to cell wall or membrane agents?
In the context of phage therapy, what is the main characteristic of bacteriophages?
In the context of phage therapy, what is the main characteristic of bacteriophages?
What was the outcome for the pediatric patient with cystic fibrosis who received a 3-phage cocktail for a Mycobacterium abscessus infection?
What was the outcome for the pediatric patient with cystic fibrosis who received a 3-phage cocktail for a Mycobacterium abscessus infection?
How did the personalized phage treatment for a patient with P. aeruginosa prosthetic joint infection differ from standard treatment?
How did the personalized phage treatment for a patient with P. aeruginosa prosthetic joint infection differ from standard treatment?
What is the percentage of E.coli isolates in the UK resistant to fluoroquinolones in the years 2001-2006?
What is the percentage of E.coli isolates in the UK resistant to fluoroquinolones in the years 2001-2006?
Which antibiotic is cited as the first choice against Legionella pneumophila?
Which antibiotic is cited as the first choice against Legionella pneumophila?
Which fluoroquinolone has been recommended by 5 ID specialists as of December 2023?
Which fluoroquinolone has been recommended by 5 ID specialists as of December 2023?
What condition can Clostridioides difficile infection potentially lead to?
What condition can Clostridioides difficile infection potentially lead to?
Which condition accounted for the most estimated unnecessary fluoroquinolone prescriptions in medical offices and EDs in 2014?
Which condition accounted for the most estimated unnecessary fluoroquinolone prescriptions in medical offices and EDs in 2014?
Which pathogen has developed resistance to many fluoroquinolones?
Which pathogen has developed resistance to many fluoroquinolones?
What can fluoroquinolone use lead to besides resistance?
What can fluoroquinolone use lead to besides resistance?
Which setting saw nearly 32 million fluoroquinolone prescriptions dispensed from U.S. outpatient pharmacies?
Which setting saw nearly 32 million fluoroquinolone prescriptions dispensed from U.S. outpatient pharmacies?
Which statement about fluoroquinolones is true?
Which statement about fluoroquinolones is true?
What is a common side effect associated with fluoroquinolones?
What is a common side effect associated with fluoroquinolones?
What is the mechanism of action of Trimethoprim?
What is the mechanism of action of Trimethoprim?
Which antibiotic is recommended by IDSA guidance for the management of initial C.difficile episodes?
Which antibiotic is recommended by IDSA guidance for the management of initial C.difficile episodes?
What is the main adverse reaction associated with Sulfonamides?
What is the main adverse reaction associated with Sulfonamides?
What is the mode of action of Fidaxomicin?
What is the mode of action of Fidaxomicin?
Why should fluoroquinolones be reserved for important uses according to IDSA guidelines?
Why should fluoroquinolones be reserved for important uses according to IDSA guidelines?
Which antibiotic is indicated for anaerobic or mixed intra-abdominal infections?
Which antibiotic is indicated for anaerobic or mixed intra-abdominal infections?
What is the primary target of Rifampin's mechanism of action?
What is the primary target of Rifampin's mechanism of action?
What is the primary target for Quinolones (Q) and Fluoroquinolones (FQs)?
What is the primary target for Quinolones (Q) and Fluoroquinolones (FQs)?
What is the mechanism of killing associated with Aminoglycosides and Fluoroquinolones?
What is the mechanism of killing associated with Aminoglycosides and Fluoroquinolones?
Which enzyme is responsible for adding negative supercoils to DNA?
Which enzyme is responsible for adding negative supercoils to DNA?
What was the first plasmid-mediated Fluoroquinolone resistance reported in?
What was the first plasmid-mediated Fluoroquinolone resistance reported in?
Which of the following is a mechanism that provides low-level protection against Fluoroquinolones?
Which of the following is a mechanism that provides low-level protection against Fluoroquinolones?
What do multiple copies of qnr genes confer resistance to in the absence of chromosomal mutations?
What do multiple copies of qnr genes confer resistance to in the absence of chromosomal mutations?
What factor affects the resistance rates of uncomplicated ESBL positive E.coli isolates to Fluoroquinolones?
What factor affects the resistance rates of uncomplicated ESBL positive E.coli isolates to Fluoroquinolones?
Which region of the topoisomerases is associated with resistance to Quinolones and Fluoroquinolones?
Which region of the topoisomerases is associated with resistance to Quinolones and Fluoroquinolones?
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