Antihypertensive Medications

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Questions and Answers

When starting a patient on lisinopril, what common adverse effect should the patient be educated to expect?

  • Muscle weakness
  • Constipation
  • Tinnitus
  • Dry, nonproductive cough (correct)

Which medication is typically recommended as first-line treatment for a newly diagnosed patient with stage 1 hypertension?

  • Diltiazem
  • Spironolactone
  • HCTZ (correct)
  • Hydralazine

A patient of which racial background is least likely to respond effectively to single-medication therapy with an ARB?

  • Asian
  • Hispanic
  • African American (correct)
  • Caucasian

A patient presents to the emergency department with a blood pressure of 240/120 mmHg. The provider orders nitroprusside. How will this medication lower blood pressure?

<p>Dilating venous and arterial vessels (D)</p> Signup and view all the answers

A patient has been receiving nitroprusside for 2 days. Which of the following adverse effects is the nurse's priority to monitor?

<p>Cyanide toxicity (A)</p> Signup and view all the answers

What side effect is most important to monitor when a patient is taking diltiazem?

<p>Orthostatic hypotension (A)</p> Signup and view all the answers

A 65-year-old Caucasian female has an average blood pressure of 148/86 mmHg. According to current guidelines, this is stage hypertension.

<p>1 (A)</p> Signup and view all the answers

Which of the following medication classes are generally considered first-line options for treating hypertension?

<p>&quot;pine&quot; calcium channel blocker (B), Thiazide diuretic (C), ACE inhibitor (D)</p> Signup and view all the answers

Which medication would be least appropriate for a patient with COPD because of its blocking effects on beta receptors?

<p>Propranolol (C)</p> Signup and view all the answers

A patient prescribed losartan should be regularly monitored for which of the following potential complications?

<p>Renal insufficiency (A)</p> Signup and view all the answers

What two factors directly determine cardiac output (CO)?

<p>Heart Rate and Stroke Volume (C)</p> Signup and view all the answers

According to the formula $BP=CO \times PR$, what are the two main determinants of blood pressure?

<p>Cardiac Output and Peripheral Resistance (B)</p> Signup and view all the answers

Which category of antihypertensive medications acts directly on the renal system to promote fluid excretion and lower blood volume?

<p>Diuretics (D)</p> Signup and view all the answers

Which class of antihypertensive drugs inhibits the conversion of Angiotensin I to Angiotensin II?

<p>ACE Inhibitors (A)</p> Signup and view all the answers

What is the mechanism of action of direct-acting vasodilators in reducing blood pressure?

<p>Relaxing smooth muscle in blood vessels (A)</p> Signup and view all the answers

Which antihypertensive drug class is known to frequently cause reflex tachycardia as an adverse effect?

<p>Direct-Acting Vasodilators (B)</p> Signup and view all the answers

Which of the following drug classes primarily works by blocking alpha-1 adrenergic receptors?

<p>Alpha-1 Blockers (C)</p> Signup and view all the answers

What potential adverse effect is associated with all antihypertensive medications?

<p>Hypotension (C)</p> Signup and view all the answers

Which of the medication classes listed works by blocking the effects of Angiotensin II on its receptors?

<p>ARBs (B)</p> Signup and view all the answers

Why are beta-blockers sometimes avoided in patients with asthma or COPD?

<p>They can cause bronchoconstriction. (A)</p> Signup and view all the answers

Flashcards

What is Cardiac Output (CO)?

Cardiac Output is the volume of blood pumped by the heart per minute.

What is stroke volume (SV)?

Stroke volume is the amount of blood ejected by the heart in each beat.

What is heart rate (HR)?

Heart rate is the number of times a heart beats per minute.

What is Blood Pressure (BP)?

Blood pressure is the force of blood against the walls of arteries.

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What is Peripheral Resistance (PR)?

Peripheral Resistance is the resistance to blood flow in the arteries.

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How do Beta Blockers work?

Beta blockers block beta-adrenergic receptors, reducing heart rate and blood pressure.

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How do ACE Inhibitors work?

ACE inhibitors block the conversion of angiotensin I to angiotensin II, preventing vasoconstriction and lower blood pressure.

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How do ARBs work?

ARBs block the action of angiotensin II, leading to vasodilation and reduced blood pressure.

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How do Calcium Channel Blockers work?

Calcium channel blockers prevent calcium from entering heart and artery cells, lowering blood pressure.

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How do Diuretics work?

Diuretics increase urine production, reducing blood volume and blood pressure.

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What is a frequent adverse effect antihypertensives?

A common adverse effect of antihypertensive medications is orthostatic hypotension.

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What is reflex tachycardia?

Some antihypertensive drugs can cause a sudden increase in heart rate as a compensatory mechanism.

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What is a common side effect of lisinopril?

Dry, nonproductive cough is a common side effect of lisinopril.

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Which diuretic is a first line treatment for hypertension?

Thiazide diuretics are often considered first-line for hypertension treatment.

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When should propranolol be avoided?

Propranolol is contraindicated in patients with COPD.

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What to monitor with losartan?

Renal insufficiency requires attention for losartan use.

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Study Notes

  • Cardiac Output (CO) is equal to Stroke Volume (SV) multiplied by Heart Rate (HR).
  • Blood Pressure (BP) is equal to Cardiac Output (CO) multiplied by Peripheral Resistance (PR).
  • Alpha-1 blockers, ACE inhibitors, ARBs, and Beta blockers are antihypertensive drug classes.
  • Other antihypertensive drug classes include calcium channel blockers, clonidine, diuretics, and direct-acting vasodilators.
  • All antihypertensives can cause adverse effects.
  • Reflex tachycardia can be associated with certain antihypertensive classes.

Multiple Choice Questions

  • When administering lisinopril, advise patients its common adverse effect of a dry, nonproductive cough.
  • HCTZ (hydrochlorothiazide) is indicated for initial treatment in a patient with newly diagnosed stage 1 hypertension.
  • Single medication therapy with an ARB would be least effective in African American people.
  • Nitroprusside lowers blood pressure by dilating venous and arterial vessels.
  • A patient receiving nitroprusside for 2 days should be monitored for cyanide toxicity.
  • A nurse would monitor for orthostatic hypotension in a person taking diltiazem.
  • A 65-year-old Caucasian female with an average blood pressure of 148/86 mmHg has Stage 1 hypertension.
  • Thiazide diuretics are considered first-line options for hypertension treatment.
  • A patient with COPD should not use propranolol.
  • A person taking losartan should be monitored for renal insufficiency.

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