Antigen Structure, Processing and Presentation by Dr. Muna Oqal
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Questions and Answers

Which of the following is NOT a characteristic of high molecular weight antigens?

  • Are usually non-protein substances
  • May be proteins or polysaccharides
  • Can induce immune response on their own (correct)
  • Require carrier molecules to induce an immune response

What is the term used to describe the immunologically active regions of an immunogen that bind to antigen-specific receptors on lymphocytes?

  • Carrier molecules
  • Epitopes (correct)
  • Determinants
  • Globulins

Why are parenteral routes of administration more immunogenic compared to the oral route?

  • They have larger molecules
  • They have a higher molecular weight
  • They contain stable molecules
  • They allow direct access to lymphocytes (correct)

What is the main property that makes a molecule more effective as an antigen?

<p>Being a stable molecule (B)</p> Signup and view all the answers

What is the role of carrier molecules in relation to incomplete antigens or haptens?

<p>Make incomplete antigens complete antigens (B)</p> Signup and view all the answers

Which characteristic does NOT contribute to the antigenicity of a molecule?

<p>Small molecular mass between 5000 and 100,000 daltons (C)</p> Signup and view all the answers

What is the main characteristic of an immunogen?

<p>It causes the generation of antibodies (B)</p> Signup and view all the answers

Which of the following is NOT a type of antigen according to the text?

<p>Hydrocarbons (C)</p> Signup and view all the answers

What is the role of Major Histocompatibility Complex (MHC) in antigen presentation?

<p>It presents antigens to T cells (B)</p> Signup and view all the answers

Which statement accurately describes haptens?

<p>Haptens only become immunogenic when coupled with carrier molecules (D)</p> Signup and view all the answers

What is the distinguishing feature of a Complete Antigen or Immunogen?

<p>It possesses antigenic properties on its own (A)</p> Signup and view all the answers

Which of the following is an example of an antigen formed within the body?

<p>Bacterial toxins (D)</p> Signup and view all the answers

What is the term used to describe the small area on the antigen molecule that reacts specifically with antibodies?

<p>Epitope (D)</p> Signup and view all the answers

Which cells are responsible for trapping viral antigens in the body fluids?

<p>Macrophages (A)</p> Signup and view all the answers

Which type of antigenic determinants are mainly recognized by T cells?

<p>Linear determinants (D)</p> Signup and view all the answers

What process mainly mediates the uptake of exogenous antigens by APCs?

<p>Phagocytosis (A)</p> Signup and view all the answers

Which type of immunogens are nucleic acids considered to be?

<p>Poorly immunogenic (D)</p> Signup and view all the answers

Which of the following is an example of endogenous antigens?

<p>Antigens generated within cells due to infection (B)</p> Signup and view all the answers

Which type of human tissue antigens include Major Histocompatibility Complex (MHC) molecules?

<p>Histocompatibility antigens (A)</p> Signup and view all the answers

What type of antigens are exogenous antigens?

<p>Antigens from outside the body (A)</p> Signup and view all the answers

Which of the following is a type of bacterial antigen related to bacterial cells?

<p>Capsular antigen (A)</p> Signup and view all the answers

What can some exogenous antigens transform into, after entering the body?

<p>Endogenous antigens (B)</p> Signup and view all the answers

Why are lipids generally considered non-immunogenic?

<p>They lack antigenic determinants (B)</p> Signup and view all the answers

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