Antifungal Drugs Mechanism of Action Quiz
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Questions and Answers

Which class of antifungal agents inhibits the synthesis of ergosterol in the fungal cell membrane?

  • Echinocandins
  • Azoles (correct)
  • Antimetabolites
  • Terbinafine
  • Which antifungal agent disrupts the fungal cell wall by inhibiting β-glucan synthesis?

  • Fluconazole
  • 5-Fluorocytosine
  • Caspofungin (correct)
  • Itraconazole
  • Which antifungal agent targets the cytochrome P450 enzyme in fungi?

  • Terbinafine
  • Flucytosine
  • Amphotericin B
  • Miconazole (correct)
  • Which antifungal agent is used to treat superficial fungal infections, such as athlete's foot and ringworm?

    <p>Terbinafine</p> Signup and view all the answers

    Which class of antifungal agents is effective against both Candida species and Aspergillus species?

    <p>Echinocandins</p> Signup and view all the answers

    Which antifungal agent is a pyrimidine analog that inhibits DNA synthesis in fungi?

    <p>Flucytosine</p> Signup and view all the answers

    Which one of these antifungal drugs inhibits the synthesis of Beta 1-3 D glucan?

    <p>Anidulafungin</p> Signup and view all the answers

    Which one of these antifungal drugs targets squalene allylamine monooxygenase?

    <p>Terbinafine</p> Signup and view all the answers

    Which one of these antifungal drugs is a potent antimetabolite that inhibits thymidylate synthase enzyme?

    <p>Flucytosine</p> Signup and view all the answers

    Which one of these antifungal drugs disrupts spindle formation (microtubule function) and is fungistatic?

    <p>Griseofulvin</p> Signup and view all the answers

    Which one of these antifungal drugs inhibits sterol 14-alpha demethylase enzyme in fungal ergosterol biosynthesis?

    <p>Fluconazole</p> Signup and view all the answers

    Which one of these antifungal drugs makes pores or channels by interacting with ergosterol on fungal membrane, causing ions to leak out?

    <p>Amphotericin B</p> Signup and view all the answers

    Which class of antifungals is characterized by their ability to inhibit the synthesis of ergosterol in fungal cell membranes?

    <p>Azoles</p> Signup and view all the answers

    Which antifungal class targets the fungal cell wall by inhibiting beta-glucan synthesis?

    <p>Echinocandins</p> Signup and view all the answers

    Which antifungal is characterized by its ability to inhibit the fungal squalene epoxidase enzyme?

    <p>Terbinafine</p> Signup and view all the answers

    Which class of antifungals works by mimicking purine or pyrimidine precursors to disrupt nucleic acid synthesis in fungi?

    <p>Antimetabolites</p> Signup and view all the answers

    Which antifungal is characterized by its ability to inhibit the synthesis of chitin in fungal cell walls?

    <p>Echinocandins</p> Signup and view all the answers

    Which antifungal class is characterized by its ability to inhibit the synthesis of DNA and RNA in fungi?

    <p>Antimetabolites</p> Signup and view all the answers

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