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Antifungal Drugs Mechanism of Action Quiz

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18 Questions

Which class of antifungal agents inhibits the synthesis of ergosterol in the fungal cell membrane?

Azoles

Which antifungal agent disrupts the fungal cell wall by inhibiting β-glucan synthesis?

Caspofungin

Which antifungal agent targets the cytochrome P450 enzyme in fungi?

Miconazole

Which antifungal agent is used to treat superficial fungal infections, such as athlete's foot and ringworm?

Terbinafine

Which class of antifungal agents is effective against both Candida species and Aspergillus species?

Echinocandins

Which antifungal agent is a pyrimidine analog that inhibits DNA synthesis in fungi?

Flucytosine

Which one of these antifungal drugs inhibits the synthesis of Beta 1-3 D glucan?

Anidulafungin

Which one of these antifungal drugs targets squalene allylamine monooxygenase?

Terbinafine

Which one of these antifungal drugs is a potent antimetabolite that inhibits thymidylate synthase enzyme?

Flucytosine

Which one of these antifungal drugs disrupts spindle formation (microtubule function) and is fungistatic?

Griseofulvin

Which one of these antifungal drugs inhibits sterol 14-alpha demethylase enzyme in fungal ergosterol biosynthesis?

Fluconazole

Which one of these antifungal drugs makes pores or channels by interacting with ergosterol on fungal membrane, causing ions to leak out?

Amphotericin B

Which class of antifungals is characterized by their ability to inhibit the synthesis of ergosterol in fungal cell membranes?

Azoles

Which antifungal class targets the fungal cell wall by inhibiting beta-glucan synthesis?

Echinocandins

Which antifungal is characterized by its ability to inhibit the fungal squalene epoxidase enzyme?

Terbinafine

Which class of antifungals works by mimicking purine or pyrimidine precursors to disrupt nucleic acid synthesis in fungi?

Antimetabolites

Which antifungal is characterized by its ability to inhibit the synthesis of chitin in fungal cell walls?

Echinocandins

Which antifungal class is characterized by its ability to inhibit the synthesis of DNA and RNA in fungi?

Antimetabolites

Test your knowledge on the mechanism of action of antifungal drugs such as Polyenes (Amphotericin B, Nystatin) and Flucytosine. Learn how these drugs interact with fungal membranes and disrupt their function. Prepare for your Pharmacology exam with this quiz.

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